| Singles | |
|---|---|
| 1997 Welsh International Open | |
| 1996 Champion |  Dominique Van Roost |
| Champion |  Virginia Ruano-Pascual |
| Runner-up |  Alexia Dechaume-Balleret |
| Final score | 6–1, 3–6, 6–2 |
Dominique Van Roost was the defending champion but lost in the quarterfinals to Rita Grande.
Virginia Ruano-Pascual won in the final 6–1, 3–6, 6–2 against Alexia Dechaume-Balleret.
A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated.
Dominique Van Roost (quarterfinals)
Åsa Carlsson (quarterfinals)
Miriam Oremans (second round)
Petra Langrová (quarterfinals) Sarah Pitkowski (semifinals)
Annabel Ellwood (first round) Denisa Chládková (first round)
Yuka Yoshida (first round)Ludmila Richterová was the defending champion but did not compete that year.
Sandra Cacic was the defending champion but lost in the quarterfinals to Tamarine Tanasugarn.
Meredith McGrath was the defending champion, but did not participate this year.
Anke Huber was the defending champion but lost in the semifinals to Miriam Oremans.
Shi-Ting Wang was the defending champion but lost in the first round to Maria Vento.
Jana Novotná was the defending champion but lost in the semifinals to Lindsay Davenport.
Ruxandra Dragomir was the defending champion of the Volvo Women's Open but lost in the semifinals to Henrieta Nagyová.
Miho Saeki and Yuka Yoshida were the defending champions but lost in the quarterfinals to Kristine Kunce and Corina Morariu.
Marion Maruska was the defending champion but lost in the first round to Meike Babel.
Janette Husárová and Dominique Van Roost were the defending champions but they competed with different partners that year, Husárová with Julie Halard-Decugis and Van Roost with Laura Golarsa.
Dominique Van Roost was the defending champion but lost in the final 6–3, 6–2 against Patty Schnyder.
Martina Hingis was the defending champion but did not compete that year.
Chanda Rubin was the defending champion, but chose not compete that year.
Amanda Coetzer was the defending champion but did not compete that year.
Mary Pierce was the defending champion but lost in the third round to Mirjana Lučić.
Jana Novotná was the defending champion but did not compete that year.
Mary Joe Fernández and Arantxa Sánchez Vicario were the defending champions but did not compete that year.
Ruxandra Dragomir was the defending champion but lost in the first round to Julie Halard-Decugis.
Martina Hingis was the defending champion, but lost in the quarterfinals to Dominique Van Roost.
The singles competition of the 2000 Direct Line International Championships was part of the 26th edition of the Eastbourne International tennis tournament, Tier II of the 2000 WTA Tour. Natasha Zvereva was the defending champion but lost in the second round to Anna Kournikova. Julie Halard-Decugis won in the final 7–6(, 6–4 against Dominique Van Roost.
