| Singles | |
|---|---|
| 2001 Betty Barclay Cup | |
| Champion |  Venus Williams |
| Runner-up | Meghann Shaughnessy |
| Final score | 6–3, 6–0 |
| Draw | 28 |
| Seeds | 8 |
Martina Hingis was the defending champion but did not compete that year.
Venus Williams won in the final 6–3, 6–0 against Meghann Shaughnessy.
A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated. The top four seeds received a bye to the second round.
Venus Williams (champion)
Amanda Coetzer (semifinals)
Conchita Martínez (second round) Arantxa Sánchez-Vicario (quarterfinals)
Magdalena Maleeva (second round)
Justine Henin (quarterfinals) Meghann Shaughnessy (final) Magüi Serna (first round)| Final | ||||||
| 1 | Venus Williams | 6 | 6 | |||
| 7 | Meghann Shaughnessy | 3 | 0 | |||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | V Williams | 6 | 6 | ||||||||||||||||||||||||
| G León García | 6 | 6 | G León García | 1 | 2 | ||||||||||||||||||||||
| Q |  M Müller | 1 | 2 | 1 | V Williams | 6 | 6 | ||||||||||||||||||||
 S Farina Elia | 6 | 7 | S Farina Elia | 1 | 1 | ||||||||||||||||||||||
| T Garbin | 4 | 5 | S Farina Elia | 6 | 6 | ||||||||||||||||||||||
| WC | A Glass | 6 | 6 | WC | A Glass | 1 | 1 | ||||||||||||||||||||
| 8 | M Serna | 4 | 3 | 1 | V Williams | 6 | 6 | ||||||||||||||||||||
 J Dokić | 3 | 1 | |||||||||||||||||||||||||
| 4 | A Sánchez-Vicario | 6 | 6 | ||||||||||||||||||||||||
| Q |  D Chládková | 6 | 6 | Q | D Chládková | 2 | 2 | ||||||||||||||||||||
 H Nagyová | 4 | 4 | 4 | A Sánchez-Vicario | 6 | 65 | 2 | ||||||||||||||||||||
| Q | B Rittner | 6 | 2 | 2 | J Dokić | 3 | 77 | 6 | |||||||||||||||||||
| J Dokić | 4 | 6 | 6 | J Dokić | 6 | 6 | |||||||||||||||||||||
 R Dragomir Ilie | 5 | 78 | 3 | 5 | M Maleeva | 1 | 1 | ||||||||||||||||||||
| 5 | M Maleeva | 7 | 66 | 6 | |||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 7 | M Shaughnessy | 6 | 6 | ||||||||||||||||||||||||
| K Brandi | 2 | 2 | 7 | M Shaughnessy | 6 | 77 | |||||||||||||||||||||
 C Black | 2 | 3 | K Hrdličková | 1 | 62 | ||||||||||||||||||||||
| K Hrdličková | 6 | 6 | 7 | M Shaughnessy | 6 | 6 | |||||||||||||||||||||
| WC |  P Schnyder | 6 | 7 | WC | P Schnyder | 4 | 4 | ||||||||||||||||||||
 B Schett | 4 | 5 | WC | P Schnyder | 6 | 2 | 6 | ||||||||||||||||||||
| 3 | C Martínez | 3 | 6 | 2 | |||||||||||||||||||||||
| 7 | M Shaughnessy | 6 | 6 | ||||||||||||||||||||||||
| 6 | J Henin | 65 | 6 | 6 | 2 | A Coetzer | 3 | 4 | |||||||||||||||||||
 A-G Sidot | 77 | 3 | 2 | 6 | J Henin | 77 | 1 | 6 | |||||||||||||||||||
 E Likhovtseva | 2 | 6 | 6 | E Likhovtseva | 63 | 6 | 2 | ||||||||||||||||||||
| Q |  Å Carlsson | 6 | 2 | 3 | 6 | J Henin | 5 | 6 | 2 | ||||||||||||||||||
| T Panova | 65 | 4 | 2 | A Coetzer | 7 | 4 | 6 | ||||||||||||||||||||
| WC | B Lamade | 77 | 6 | WC | B Lamade | 6 | 3 | 1 | |||||||||||||||||||
| 2 | A Coetzer | 2 | 6 | 6 | |||||||||||||||||||||||
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