| Singles | |
|---|---|
| 2006 Grand Prix de Tennis de Lyon | |
| Champion |  Richard Gasquet |
| Runner-up | Marc Gicquel |
| Final score | 6–3, 6–1 |
Andy Roddick was the defending champion, but did not participate this year.
Richard Gasquet won the tournament, beating Marc Gicquel 6–3, 6–1 in the final.
Marcos Baghdatis (first round)
Gastón Gaudio (first round)
Dominik Hrbatý (second round) Richard Gasquet (champion)
Robin Söderling (quarterfinals) Sébastien Grosjean (quarterfinals)
Xavier Malisse (semifinals)
Nicolás Almagro (quarterfinals)| Semifinals | Final | ||||||||||||
| Arnaud Clément | 78 | 4 | 1 | ||||||||||
| 4 | Richard Gasquet | 66 | 6 | 6 | |||||||||
| 4 | Richard Gasquet | 6 | 6 | ||||||||||
| Marc Gicquel | 3 | 1 | |||||||||||
| Marc Gicquel | 6 | 1 | 77 | ||||||||||
| 7 | Xavier Malisse | 4 | 6 | 65 | |||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | M Baghdatis | 2 | 7 | 3 | |||||||||||||||||||||||
| A Clément | 6 | 5 | 6 | A Clément | 2 | 6 | 77 | ||||||||||||||||||||
| WC | M Llodra | 4 | 77 | 6 | WC | M Llodra | 6 | 1 | 62 | ||||||||||||||||||
| Q | M Mertiňák | 6 | 64 | 2 | A Clément | 6 | 6 | ||||||||||||||||||||
| N Mahut | 65 | 3 | 8 | N Almagro | 3 | 2 | |||||||||||||||||||||
 F Mayer | 77 | 6 | F Mayer | 65 | 4 | ||||||||||||||||||||||
 O Marach | 6 | 5 | 1 | 8 | N Almagro | 77 | 6 | ||||||||||||||||||||
| 8 | N Almagro | 2 | 7 | 6 | A Clément | 78 | 4 | 1 | |||||||||||||||||||
| 4 | R Gasquet | 6 | 77 | 4 | R Gasquet | 66 | 6 | 6 | |||||||||||||||||||
 M Safin | 4 | 65 | 4 | R Gasquet | 6 | 6 | |||||||||||||||||||||
| D Norman | 6 | 7 | D Norman | 3 | 4 | ||||||||||||||||||||||
| WC | O Patience | 4 | 5 | 4 | R Gasquet | 4 | 6 | 6 | |||||||||||||||||||
 N Massú | 78 | 7 | 5 | R Söderling | 6 | 3 | 3 | ||||||||||||||||||||
 K Kim | 66 | 5 | N Massú | 5 | 3 | ||||||||||||||||||||||
| WC | T Ascione | 3 | 1 | 5 | R Söderling | 7 | 6 | ||||||||||||||||||||
| 5 | R Söderling | 6 | 6 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 6 | S Grosjean | 6 | 77 | ||||||||||||||||||||||||
| P-H Mathieu | 3 | 63 | 6 | S Grosjean | 77 | 6 | |||||||||||||||||||||
| Q |  A Falla | 711 | 3 | 2 | Q | C Saulnier | 65 | 2 | |||||||||||||||||||
| Q | C Saulnier | 69 | 6 | 6 | 6 | S Grosjean | 5 | 6 | 65 | ||||||||||||||||||
| M Gicquel | 6 | 6 | M Gicquel | 7 | 1 | 77 | |||||||||||||||||||||
 A Seppi | 4 | 3 | M Gicquel | 6 | 6 | ||||||||||||||||||||||
| F Serra | 6 | 3 | 3 | 3 | D Hrbatý | 3 | 3 | ||||||||||||||||||||
| 3 | D Hrbatý | 3 | 6 | 6 | M Gicquel | 6 | 1 | 77 | |||||||||||||||||||
| 7 | X Malisse | 6 | 4 | 6 | 7 | X Malisse | 4 | 6 | 65 | ||||||||||||||||||
| V Spadea | 3 | 6 | 1 | 7 | X Malisse | 6 | 77 | ||||||||||||||||||||
| J Benneteau | 7 | 6 | J Benneteau | 2 | 65 | ||||||||||||||||||||||
| Q | J Mathieu | 5 | 4 | 7 | X Malisse | 6 | 6 | ||||||||||||||||||||
| R Ginepri | 77 | 77 | R Ginepri | 4 | 3 | ||||||||||||||||||||||
| G Simon | 63 | 65 | R Ginepri | 6 | 6 | ||||||||||||||||||||||
| S Greul | 6 | 6 | S Greul | 1 | 2 | ||||||||||||||||||||||
| 2 | G Gaudio | 0 | 2 | ||||||||||||||||||||||||
Richard Gasquet was the defending champion, but lost in the second round to Jo-Wilfried Tsonga.
Novak Djokovic defeated Richard Gasquet 7–6(9–7), 0–6, 6–1 to win the 2007 Estoril Open singles event.
Dmitry Tursunov was the defending champion, but chose not to participate that year.
Roger Federer was the defending champion, but chose not to participate in the 2007 event.
Ivan Ljubičić was the defending champion, but lost in the quarterfinals to Andreas Seppi.
Lleyton Hewitt was the defending champion, but lost in the quarterfinals to Andreas Seppi.
Jonas Björkman and Max Mirnyi were the defending champions, but lost in quarterfinals to Julien Benneteau and Richard Gasquet.
Thomaz Bellucci was the defending champion, however he lost to Marco Chiudinelli in the first round.
Nicolás Almagro won in the final 7–5, 6–1, against Richard Gasquet.
Gastón Gaudio was the defending champion but lost in the quarterfinals to Richard Gasquet.
Juan Martín del Potro defended the title by winning 6–4, 6–2 against Richard Gasquet.
Andy Murray was the defending champion but decided not to participate.
Richard Gasquet won the title beating Gilles Simon in an all-French final, 6–2, 6–1.
Paradorn Srichaphan was the defending champion, but lost in the quarterfinals this year.
Tomáš Berdych was the defending champion but withdrew because of a wrist injury.
Richard Gasquet won the title, defeating Benoît Paire in an all-French final, 6–2, 6–3.
Richard Gasquet was the defending champion, but lost to Milos Raonic in the semifinals.
Raonic went on to win the title, defeating Tomáš Berdych in the final, 7–6(7–4), 6–3.
Jérôme Haehnel was the defending champion, but did not participate.
Gaël Monfils was the defending champion, but lost to Richard Gasquet in the semifinals.
Gasquet went on to win the title, defeating Jerzy Janowicz in the final, 3–0, ret.
Tomáš Berdych was the defending champion and successfully defended his title, defeating Richard Gasquet in the final, 7−6(7−5), 6−7(2−7), 6−3.
Alexander Zverev was the defending champion, but chose not to participate this year.
Gilles Müller was the defending champion, but lost in the second round to Matthew Ebden.
Dušan Lajović was the reigning champion from when the tournament was last held in 2019, but lost to Daniel Altmaier in the quarterfinals.