| Singles | |
|---|---|
| 2010 Tennis Napoli Cup | |
| Champion |  Rui Machado |
| Runner-up |  Federico Delbonis |
| Final score | 6–4, 6–4 |
Pablo Cuevas was the defending champion, however he chose not to participate this year.
Rui Machado won the title, defeating Federico Delbonis 6–4, 6–4 in the final.
Potito Starace (second round) Paolo Lorenzi (second round)
Andrey Golubev (semifinals)
Blaž Kavčič (first round)
Igor Kunitsyn (first round)
Pere Riba (withdrew)
Victor Crivoi (first round) Rui Machado (champion)| Semifinals | Final | ||||||||||||
| Federico Delbonis | 6 | 6 | |||||||||||
| Q |  Adrián García | 3 | 4 | ||||||||||
| Federico Delbonis | 4 | 4 | |||||||||||
| 8 | Rui Machado | 6 | 6 | ||||||||||
| 3 | Andrey Golubev | 3 | 3 | ||||||||||
| 8 | Rui Machado | 6 | 6 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1/WC | P Starace | 6 | 6 | ||||||||||||||||||||||||
| S Decoud | 4 | 0 | 1/WC | P Starace | 5 | 3 | |||||||||||||||||||||
| F Delbonis | 77 | 6 | F Delbonis | 7 | 6 | ||||||||||||||||||||||
| F Cipolla | 64 | 4 | F Delbonis | 7 | 1 | 78 | |||||||||||||||||||||
 I Minář | 78 | 6 | I Minář | 5 | 6 | 66 | |||||||||||||||||||||
 D Brown | 66 | 2 | I Minář | 7 | 4 | 77 | |||||||||||||||||||||
| WC | M Trevisan | 4 | r | LL | M Alund | 5 | 6 | 62 | |||||||||||||||||||
| LL | M Alund | 5 | F Delbonis | 6 | 6 | ||||||||||||||||||||||
| 4 | B Kavčič | 4 | 1 | Q | A García | 3 | 4 | ||||||||||||||||||||
| A Ramos-Viñolas | 6 | 6 | A Ramos-Viñolas | 6 | 6 | ||||||||||||||||||||||
| M Vassallo Argüello | 6 | 77 | M Vassallo Argüello | 2 | 4 | ||||||||||||||||||||||
| LL | J-M Aranguren | 2 | 64 | A Ramos-Viñolas | 68 | 2 | |||||||||||||||||||||
| S Bolelli | 6 | 6 | Q | A García | 710 | 6 | |||||||||||||||||||||
| ALT | M Kukushkin | 4 | 2 | S Bolelli | 4 | 4 | |||||||||||||||||||||
| Q | A García | 7 | 6 | Q | A García | 6 | 6 | ||||||||||||||||||||
| 7 | V Crivoi | 5 | 0 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 5 | I Kunitsyn | 0 | 4 | ||||||||||||||||||||||||
| A Ungur | 6 | 6 | A Ungur | 4 | 0 | ||||||||||||||||||||||
| Q | J Aguilar | 60 | 5 | F Volandri | 6 | 6 | |||||||||||||||||||||
| F Volandri | 77 | 7 | F Volandri | 4 | 65 | ||||||||||||||||||||||
 I Bozoljac | 2 | 6 | 4 | 3 | A Golubev | 6 | 77 | ||||||||||||||||||||
| P Andújar | 6 | 3 | 6 | P Andújar | 6 | 4 | 0 | ||||||||||||||||||||
| Q | A Arnaboldi | 4 | 3 | 3 | A Golubev | 3 | 6 | 6 | |||||||||||||||||||
| 3 | A Golubev | 6 | 6 | 3 | A Golubev | 3 | 3 | ||||||||||||||||||||
| 8 | R Machado | 6 | 6 | 8 | R Machado | 6 | 6 | ||||||||||||||||||||
 M Fischer | 3 | 2 | 8 | R Machado | 6 | 6 | |||||||||||||||||||||
| Q | F Aldi | 0 | 6 | 3 | WC | T Fabbiano | 3 | 0 | |||||||||||||||||||
| WC | T Fabbiano | 6 | 4 | 6 | 8 | R Machado | 6 | 2 | 6 | ||||||||||||||||||
 J Witten | 3 | 1 | D Junqueira | 3 | 6 | 1 | |||||||||||||||||||||
| D Junqueira | 6 | 6 | D Junqueira | 6 | 6 | ||||||||||||||||||||||
| WC |  B Tomic | 2 | 4 | 2 | P Lorenzi | 1 | 3 | ||||||||||||||||||||
| 2 | P Lorenzi | 6 | 6 | ||||||||||||||||||||||||
Nicolás Almagro was the defending champion, but lost in the quarterfinals to Frederico Gil.
Tommy Robredo was the defending champion, but he chose to compete in the 2010 ABN AMRO World Tennis Tournament instead.
Juan Carlos Ferrero won in the final 6–1, 6–0 against Łukasz Kubot.
Rui Machado was the defending champion, but he lost in the final 5–7, 2–6 against Oleksandr Dolgopolov Jr.
Iván Navarro was the defending champion, but he chose to not defend his title.
In the final Rui Machado defeated 6–2, 6–7(6), 6–3 David Marrero.
Laurent Recouderc was the defending champion, but he lost to Bastian Knittel in the second round.
Rubén Ramírez Hidalgo won in the final 6–4, 6–4, against her compatriot Marcel Granollers.
Gastón Gaudio was the defending champion, but he chose not to compete due to a foot injury.
José Acasuso won in the final 6–3, 6–4 against Daniel Brands.
Nicolas Devilder was the defending champion, but he did not participate that year.
Oleksandr Dolgopolov Jr., who received a special exempt into the main draw, became the first champion of this tournament. He defeated 3rd-seeded Pablo Andújar 6–4, 6–2 in the final.
Paul Capdeville was the defending champion, but he was eliminated by Franco Ferreiro in the second round.
Thomaz Bellucci defeated Nicolás Lapentti 6–4, 6–4 in the final match.
Ramón Delgado was the defending champion. This year he reached the final, losing, however, to 7th seed Rui Machado 2–6, 6–3, 5–7.
Leonardo Mayer chose to not defend his 2008 title.
Juan Ignacio Chela became the new champion, by beating João Souza 6–4, 4–6, 6–4 in the final match.
Jarkko Nieminen was the defending champion, but chose not to compete this year.
Rui Machado defeated Maxime Teixeira 6–3, 6–7(7–9), 6–4 in the final.
Blaž Kavčič was the defending champion, but he lost to Paolo Lorenzi 6–4, 1–6, 4–6 in the quarterfinals.
Rui Machado won in the final against Grega Žemlja 6–3, 6–0.
Denis Gremelmayr was the defending champion. Vincent Millot defeated him in the second round.
Rui Machado won the final 6–3, 6–3, against Jerzy Janowicz.
Jesse Huta Galung was the defending champion, but lost against eventual finalist Leonardo Mayer in the first round.
Pablo Cuevas was the defending champion but decided not to participate.
Thomas Schoorel was the defending champion.
Roberto Bautista-Agut won the final 6–7(7–9), 6–4, 6–3 against Rui Machado.
Rui Machado was the defending champion but decided not to participate.
Victor Hănescu won the title, defeating Iñigo Cervantes Huegun 6–4, 7–5 in the final.
Juan Martín del Potro was the defending champion, but withdrew before the tournament, because of illness.
Stanislas Wawrinka defeated David Ferrer 6–1, 6–4 in the final to win the title.
Defending champion Kei Nishikori successfully defended his title, defeating Pablo Andújar in the final, 6–4, 6–4, to win the Singles title at the 2015 Barcelona Open.