Kevin Anderson was the defending champion, but chose to compete in Munich instead.
Gastón Gaudio won in the final 7–5, 6–0, against Martín Vassallo Argüello.
Kristof Vliegen was the defending champion; however, he chose to not play this year.
Denis Gremelmayr defeated Thomas Schoorel in the final 7–5, 6–4.
Xavier Malisse was the defending champion, but chose to compete in ATP 250: Los Angeles instead.
Tobias Kamke defeated Milos Raonic 6–3, 7–6(4) in the final.
Marcos Baghdatis was the defending champion, but chose to compete in ATP 500 in Washington instead.
Dudi Sela won the title, defeating Ričardas Berankis 7–5, 6–2 in the finals.
In the singles event of the 2012 Heineken Open men's tennis tournament, David Ferrer was the defending champion and confirmed his title beating unseeded player Olivier Rochus in the final, 6–3, 6–4, for his 3rd win in Auckland.
The 2012 Sony Ericsson Open was a tennis tournament played at Key Biscayne, Miami, Florida from March 19 to April 1, 2012. It was the 28th edition of the Sony Ericsson Open and was played on hard courts at the Tennis Center at Crandon Park. The event was part of the 2012 ATP World Tour and 2012 WTA Tour. Novak Djokovic was the defending champion, and successfully defended his title by defeating Andy Murray 6–1, 7–6(7–4) in the final. It was Djokovic's third Sony Ericsson Open title.
Lukáš Rosol was the defending champion but lost in the quarterfinals.
Horacio Zeballos won the title 1–6, 6–4, 7–6(8–6) in the final against Martin Kližan.
Lukáš Rosol was the defending champion but decided not to participate.
Thomaz Bellucci defeated Tobias Kamke 7–6(7–4), 6–3 in the final to win the tournament.
Tobias Kamke was the defending champion but was defeated by Evgeny Donskoy in the semifinals.
Donskoy won the title by defeating Jan-Lennard Struff 6–2, 4–6, 6–1 in the final.
Roger Federer was the defending champion, but lost in the quarterfinals to Julien Benneteau.
Juan Martín del Potro won the title, defeating Benneteau in the final 7–6(7–2), 6–3.
Roger Federer was the defending champion, but lost to Kei Nishikori in the third round.
This edition of the Madrid Masters was the first since 2001 to not feature either of the top two seeds in the quarterfinal stages, after World No. 1 Novak Djokovic was defeated in the second round by Grigor Dimitrov.
Rafael Nadal won the title, defeating Stanislas Wawrinka in the final, 6–2, 6–4.
Lukáš Rosol was the defending champion, but lost in the final to Grigor Dimitrov 7–6(7–2), 6–1
João Sousa was the defending champion but chose not to compete.
Tomáš Berdych was the defending champion, but lost to Stan Wawrinka in the final, 6–4, 3–6, 4–6.
Grigor Dimitrov was the defending champion, but chose not to participate this year.
Guillermo García-López won the title, defeating Jiří Veselý in the final, 7–6(7–5), 7–6(13–11).
Guillermo García-López was the defending champion, but lost in the semifinals to Fernando Verdasco.
Andy Murray was the defending champion, but chose not to participate this year.
John Isner was the three-time defending champion, but lost in the final to Nick Kyrgios, 6–7(3–7), 6–7(4–7).
Tomáš Berdych was the two-time defending champion, but chose not to participate this year.
Diego Schwartzman was the defending champion, but lost in the semifinals to Marin Čilić.
