Brian Dabul chose to not defend his 2008 title.
Santiago Giraldo defeated Paolo Lorenzi in the final 6–2, 6–7(3), 6–2.
Santiago Giraldo was the defending champion, but decided not to participate.
Paolo Lorenzi defeated Rogério Dutra da Silva 7–5, 6–2 in the final.
Carlos Berlocq successfully defended his last year's title. He defeated Filippo Volandri 6–3, 6–1 in the final.
Blaž Kavčič was the defending champion, but lost to his compatriot Aljaž Bedene in the second round.
James Blake was the defending champion.
Sam Querrey won the final after defeating Paolo Lorenzi 6–1, 6–7(3–7), 6–3 in the final.
Víctor Estrella was the defending champion but did not participate.
Paolo Lorenzi defeated Leonardo Mayer 7–6(7–5), 6–7(4–7), 6–4 in the final to win the title.
Paolo Lorenzi was the defending champion, but was defeated eventual champion Pablo Carreño Busta, who defeated Grégoire Burquier 6–4, 6–4 in the final
Horacio Zeballos was the defending champion but decided not to participate.
Thomaz Bellucci won the title over Diego Sebastián Schwartzman
Tennis player Alejandro Falla was the 2012 Open Seguros Bolívar defending champion.
Rafael Nadal was the defending champion but chose not to compete.
Nicolas Mahut was the defending champion, but lost in the quarterfinals to Roberto Bautista Agut.
Bautista Agut went on to win the title, defeating Benjamin Becker in the final, 2–6, 7–6(7–2), 6–4.
Leonardo Mayer was the two-time defending champion, but he did not participate that year.
Pablo Cuevas won the title, after Paolo Lorenzi withdrew from the final.
Guillermo García-López and Philipp Oswald were the defending champions, but García-López chose not to participate this year. Oswald played alongside Martin Kližan, but they lost in the first round to Carlos Berlocq and Leonardo Mayer.
Juan Sebastián Cabal and Robert Farah won the title, defeating Paolo Lorenzi and Diego Schwartzman in the final, 6–4, 6–2.
Paolo Lorenzi was the defending champion, but lost in the semifinals.
Filip Krajinović was the defending champion, but he lost in the quarterfinals to Máximo González.
Jarkko Nieminen and André Sá were the defending champions, but Nieminen did not compete due to his retirement from professional tennis. Sá played alongside Máximo González, but lost in the first round to Gero Kretschmer and Alexander Satschko.
Juan Sebastián Cabal and Robert Farah won the title, defeating Iñigo Cervantes and Paolo Lorenzi in the final, 6–3, 6–0.
Philipp Kohlschreiber was the defending champion, but lost in the second round to Karen Khachanov.
Filip Krajinović was the defending champion but lost in the quarterfinals to Paolo Lorenzi.
Víctor Estrella Burgos was the two-time defending champion and successfully defended his title, defeating Paolo Lorenzi in the final, 6–7(2–7), 7–5, 7–6(8–6).
Paolo Lorenzi was the defending champion, but lost in the second round to João Sousa.
