3 February | 1 | Bradford Bulls | A | Odsal Stadium | L | 6–40 | Collis | Sykes | 10,263 | RLP |
9 February | 2 | Hull Kingston Rovers | H | Rapid Solicitors Stadium | W | 36–20 | Cockayne (3), Aiton, Collis, Fox, Lyne | Sykes (4) | 9,237 | RLP |
17 February | 3 | London Broncos | A | The Stoop | W | 28–0 | Cockayne (2), Fox, Kirmond, Mathers | Sykes (4) | 1,887 | RLP |
24 February | 4 | Huddersfield Giants | H | Rapid Solicitors Stadium | L | 16–18 | Cockayne, Fox, L. Smith | Sykes (2) | 8,467 | RLP |
2 March | 5 | Catalans Dragons | A | Stade Gilbert Brutus | L | 22–29 | Collis, Fox, Mathers, L. Smith | Sykes (3) | 7,191 | RLP |
10 March | 6 | Salford City Reds | H | Rapid Solicitors Stadium | D | 23–23 | Cockayne, Collis, Fox, Mariano, Washbrook | Sykes (1 + FG) | 6,986 | RLP |
15 March | 7 | St Helens | A | Langtree Park | L | 18–52 | Cockayne, Collis, Mathers | Sykes (3) | 11,211 | RLP |
29 March | 9 | Castleford Tigers | A | The Jungle | W | 37–16 | Fox (2), Kirmond, Mathers, L. Smith, T. Smith | Sykes (4 + FG), L. Smith (2) | 7,705 | RLP |
1 April | 10 | Hull F.C. | H | Rapid Solicitors Stadium | L | 22–34 | Collis, Fox, Kirmond, L. Smith | Sykes (3) | 8,126 | RLP |
7 April | 11 | Wigan Warriors | A | DW Stadium | L | 24–44 | Aiton, Mathers, Mellars, L. Smith | Sykes (4) | 12,152 | RLP |
14 April | 12 | Warrington Wolves | H | Rapid Solicitors Stadium | L | 34–41 | Fox (2), Sykes (2), Lyne, Wood | Sykes (5) | 7,985 | RLP |
20 April | 13 | Widnes Vikings | A | Halton Stadium | W | 28–26 | Aiton, Cockayne, L. Smith, T. Smith, Wilkes | Sykes (3), L. Smith | 5,405 | RLP |
4 May | 14 | Catalans Dragons | H | Rapid Solicitors Stadium | W | 30–12 | Fox (2), Kirmond (2), Cockayne | L. Smith (5) | 6,125 | RLP |
19 May | 15 | Hull Kingston Rovers | A | Craven Park | L | 18–44 | Cockayne, Collis, L. Smith | L. Smith (3) | 6,933 | RLP |
25 May | 16 | Castleford Tigers | N | City of Manchester Stadium | L | 24–49 | Collis (2), Annakin, Kirmond | L. Smith (4) | 30,793 | RLP |
2 June | 17 | Wigan Warriors | H | Rapid Solicitors Stadium | L | 23–36 | Kirmond (2), Collins, Wood | L. Smith (2 + FG), Cockayne | 8,459 | RLP |
10 June | 18 | Salford City Reds | A | Salford City Stadium | W | 46–10 | Aiton, Cockayne, Collins, Fox, Kirmond, Mathers, Mathers, Sykes, Wilkes | L. Smith (7) | 2,327 | RLP |
23 June | 19 | London Broncos | H | Rapid Solicitors Stadium | W | 46–14 | Kirmond (3), Fox, Mariano, Mathers, Sykes, Wood | L. Smith (7) | 8,203 | RLP |
1 July | 20 | Hull F.C. | A | KC Stadium | W | 27–26 | Fox (2), L. Smith, Sykes, Wilkes | L. Smith (3 + FG) | 10,000 | RLP |
8 July | 21 | Widnes Vikings | H | Rapid Solicitors Stadium | W | 24–14 | Collins, Lauit'iti, Mariano, Wildie | L. Smith (4) | 7,543 | RLP |
19 July | 22 | Leeds Rhinos | A | Headingley Stadium | L | 18–20 | Lauit'iti, Mariano, Raleigh | L. Smith (3) | 18,387 | RLP |
26 July | 8 | Leeds Rhinos | H | Rapid Solicitors Stadium | L | 24–31 | Aiton, Mariano, Poore | L. Smith (4) | 10,031 | RLP |
4 August | 23 | Bradford Bulls | H | Rapid Solicitors Stadium | L | 24–26 | Fox, Lyne, Mariano, L. Smith | L. Smith (4) | 8,084 | RLP |
10 August | 24 | Warrington Wolves | A | Halliwell Jones Stadium | L | 14–26 | Kay, Kirmond, Mariano | L. Smith | 9,250 | RLP |
18 August | 25 | St Helens | H | Rapid Solicitors Stadium | L | 12–26 | Amor, Lyne | Goulding, L. Smith | 7,985 | RLP |
18 August | 25 | Huddersfield Giants | A | Kirklees Stadium | L | 0–40 | | | 8,757 | RLP |
8 September | 27 | Castleford Tigers | H | Rapid Solicitors Stadium | W | 36–32 | Kay (3), Mariano (2), Lauiti'iti, Trout | L. Smith (3), Cockayne | 6,404 | RLP |