| Singles | |
|---|---|
| 2016 Charlottesville Men's Pro Challenger | |
| Champion |  Reilly Opelka |
| Runner-up |  Ruben Bemelmans |
| Final score | 6–4, 2–6, 7–6(7–5) |
Noah Rubin was the defending champion but lost in the first round to Peter Polansky.
Reilly Opelka won the title after defeating Ruben Bemelmans 6–2, 4–6, 7–6(7–5) in the final.
Frances Tiafoe (second round) Jared Donaldson (quarterfinals) Bjorn Fratangelo (second round) Denis Kudla (quarterfinals) Tim Smyczek (quarterfinals)
Henri Laaksonen (semifinals)
Peter Polansky (quarterfinals) Dennis Novikov (first round)| Semifinals | Final | ||||||||||||
| WC | Mackenzie McDonald | 3 | 4 | ||||||||||
| Reilly Opelka | 6 | 6 | |||||||||||
| Reilly Opelka | 6 | 2 | 77 | ||||||||||
| Ruben Bemelmans | 4 | 6 | 65 | ||||||||||
| Ruben Bemelmans | 4 | 6 | 77 | ||||||||||
| 6 | Henri Laaksonen | 6 | 4 | 63 | |||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | F Tiafoe | 6 | 2 | 6 | |||||||||||||||||||||||
| WC | R Shane | 3 | 6 | 4 | 1 | F Tiafoe | 0 | 3 | |||||||||||||||||||
| WC | M McDonald | 77 | 77 | WC | M McDonald | 6 | 6 | ||||||||||||||||||||
| Q | Gonzales Austin | 60 | 62 | WC | M McDonald | 7 | 6 | ||||||||||||||||||||
| A Krajicek | 77 | 6 | 7 | P Polansky | 5 | 4 | |||||||||||||||||||||
 E Corrie | 63 | 4 | A Krajicek | 2 | 4 | ||||||||||||||||||||||
| N Rubin | 3 | 2 | 7 | P Polansky | 6 | 6 | |||||||||||||||||||||
| 7 | P Polansky | 6 | 6 | WC | M McDonald | 3 | 4 | ||||||||||||||||||||
| 4 | D Kudla | 6 | 6 | R Opelka | 6 | 6 | |||||||||||||||||||||
| T Paul | 1 | 2 | 4 | D Kudla | 6 | 6 | |||||||||||||||||||||
| WC |  C Söderlund | 77 | 4 | 6 | WC | C Söderlund | 4 | 1 | |||||||||||||||||||
 S Groth | 61 | 6 | 2 | 4 | D Kudla | 3 | 67 | ||||||||||||||||||||
| S Bangoura | 7 | 5 | 4 | R Opelka | 6 | 79 | |||||||||||||||||||||
| R Opelka | 5 | 7 | 6 | R Opelka | 6 | 65 | 6 | ||||||||||||||||||||
| M Mmoh | 6 | 6 | M Mmoh | 4 | 77 | 3 | |||||||||||||||||||||
| 8 | D Novikov | 3 | 2 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 5 | T Smyczek | 6 | 2 | 6 | |||||||||||||||||||||||
| Q | T-S Kwiatkowski | 4 | 6 | 3 | 5 | T Smyczek | 7 | 6 | |||||||||||||||||||
| B Baker | 6 | 6 | B Baker | 5 | 4 | ||||||||||||||||||||||
 T van Rijthoven | 4 | 2 | 5 | T Smyczek | 2 | 4 | |||||||||||||||||||||
 S Barry | 1 | 2 | R Bemelmans | 6 | 6 | ||||||||||||||||||||||
| R Bemelmans | 6 | 6 | R Bemelmans | 65 | 6 | 6 | |||||||||||||||||||||
| J De Loore | 63 | 2 | 3 | B Fratangelo | 77 | 4 | 2 | ||||||||||||||||||||
| 3 | B Fratangelo | 77 | 6 | R Bemelmans | 4 | 6 | 77 | ||||||||||||||||||||
| 6 | H Laaksonen | 6 | 77 | 6 | H Laaksonen | 6 | 4 | 63 | |||||||||||||||||||
| Q |  Y Bhambri | 3 | 63 | 6 | H Laaksonen | 6 | 78 | ||||||||||||||||||||
| T Sandgren | 6 | 66 | 6 | T Sandgren | 1 | 66 | |||||||||||||||||||||
| B Klein | 4 | 78 | 1 | 6 | H Laaksonen | 6 | 7 | ||||||||||||||||||||
| L Broady | 6 | 3 | 6 | 2 | J Donaldson | 3 | 5 | ||||||||||||||||||||
| Q | JC Aragone | 1 | 6 | 3 | L Broady | 4 | 63 | ||||||||||||||||||||
| WC | A Ritschard | 2 | 6 | 3 | 2 | J Donaldson | 6 | 77 | |||||||||||||||||||
| 2 | J Donaldson | 6 | 3 | 6 | |||||||||||||||||||||||
Marin Čilić was the defending champion, and won in the final over Stanislas Wawrinka, 7–6(7–2), 7–6(7–3).
Giovanni Lapentti tried to defend his 2008 title, but he was eliminated by Santiago Giraldo in the quarterfinals.
Carlos Salamanca became the new champion, after beating Sebastián Decoud 7–6(4), 6–7(5), 6–4 in the final.
Rik de Voest was the defending champion but decided not to participate.
Fritz Wolmarans won the final against Bobby Reynolds 6–7(2), 6–3, 7–6(3).
Rogério Dutra da Silva won the first edition of the tournament against Peter Polansky 6–3, 6–0 in the final.
Juan Mónaco was the defending champion, but lost to John Isner in the semifinals.
Isner went on to win the title, defeating Nicolás Almagro in the final, 6–3, 7–5.
Ryan Harrison was the defending champion, but did not participate.
This was the first edition of the tournament.
Kei Nishikori was the four-time defending champion, but chose to compete in Buenos Aires instead.
Juan Mónaco was the defending champion, but lost in the first round to Dustin Brown.
Quentin Halys was the defending champion but chose not to defend his title.
Go Soeda was the defending champion but chose not to defend his title.
Peter Polansky was the defending champion but lost in the final to Denis Shapovalov.
Frances Tiafoe was the defending champion but chose not to defend his title.
Juan Martín del Potro defeated the defending champion Roger Federer in the final, 6–4, 6–7(8–10), 7–6(7–2), to win the men's singles title at the 2018 Indian Wells Masters. Del Potro saved three championship points en route to his first ATP Tour Masters 1000 title, having been a runner-up on three previous occasions.
Dudi Sela was the defending champion but chose not to defend his title.
Juan Martín del Potro was the two-time defending champion but chose not to defend his title.
Tim Smyczek was the defending champion but lost in the second round to Thai-Son Kwiatkowski.
Steve Johnson was the two-time defending champion, but lost in the second round to Daniel Elahi Galán.
Peter Polansky was the defending champion but lost in the semifinals to Yasutaka Uchiyama.
Mikael Torpegaard was the defending champion but lost in the quarterfinals to Roberto Quiroz.