| Men's singles | |
|---|---|
| 2016 Dunlop World Challenge | |
| Champion |  James Duckworth |
| Runner-up |  Tatsuma Ito |
| Final score | 7–5, 4–6, 6–1 |
Yoshihito Nishioka was the defending champion but lost in the quarterfinals to James Duckworth.
Duckworth won the title after defeating Tatsuma Ito 7–5, 4–6, 6–1 in the final.
Yoshihito Nishioka (quarterfinals) Yūichi Sugita (second round) Go Soeda (second round)
Chung Hyeon (second round) James Duckworth (champion) Lee Duck-hee (second round) Tatsuma Ito (final) Hiroki Moriya (second round)| Semifinals | Final | ||||||||||||
| 5 | James Duckworth | 6 | 77 | ||||||||||
 Daniel Masur | 3 | 63 | |||||||||||
| 5 | James Duckworth | 7 | 4 | 6 | |||||||||
| 7 | Tatsuma Ito | 5 | 6 | 1 | |||||||||
| Luke Saville | 77 | 3 | 4 | ||||||||||
| 7 | Tatsuma Ito | 65 | 6 | 6 | |||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | Y Nishioka | 6 | 6 | ||||||||||||||||||||||||
| S-c Hong | 3 | 3 | 1 | Y Nishioka | 6 | 6 | |||||||||||||||||||||
 L Lokoli | 64 | 5 | J-P Smith | 4 | 4 | ||||||||||||||||||||||
| J-P Smith | 77 | 7 | 1 | Y Nishioka | 3 | 2 | |||||||||||||||||||||
 A Weintraub | 62 | 2 | 5 | J Duckworth | 6 | 6 | |||||||||||||||||||||
| Yuya Kibi | 77 | 6 | Y Kibi | 4 | 4 | ||||||||||||||||||||||
| A Michon | 3 | 4 | 5 | J Duckworth | 6 | 6 | |||||||||||||||||||||
| 5 | J Duckworth | 6 | 6 | 5 | J Duckworth | 6 | 77 | ||||||||||||||||||||
| 4 | H Chung | 6 | 6 | D Masur | 3 | 63 | |||||||||||||||||||||
| Shuichi Sekiguchi | 1 | 3 | 4 | H Chung | 5 | 3 | |||||||||||||||||||||
| WC | Y Takahashi | 6 | 7 | WC | Y Takahashi | 7 | 6 | ||||||||||||||||||||
| Y Uchiyama | 3 | 5 | WC | Y Takahashi | 6 | 4 | 5 | ||||||||||||||||||||
| D Masur | 2 | 6 | 6 | D Masur | 4 | 6 | 7 | ||||||||||||||||||||
 T Chen | 6 | 4 | 4 | D Masur | 6 | 6 | |||||||||||||||||||||
| T Niki | 4 | 4 | 8 | H Moriya | 2 | 3 | |||||||||||||||||||||
| 8 | H Moriya | 6 | 6 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 6 | D-h Lee | 77 | 4 | 7 | |||||||||||||||||||||||
| Q |  M Przysiężny | 63 | 6 | 5 | 6 | D-h Lee | 3 | 6 | 3 | ||||||||||||||||||
| WC | Makoto Ochi | 1 | 1 | L Saville | 6 | 3 | 6 | ||||||||||||||||||||
| L Saville | 6 | 6 | L Saville | 6 | 6 | ||||||||||||||||||||||
| Q | Y-k Lim | 6 | 2 | 6 | Q | Y-k Lim | 4 | 0 | |||||||||||||||||||
| S-w Kwon | 4 | 6 | 1 | Q | Y-k Lim | 6 | 4 | 7 | |||||||||||||||||||
| Kim Cheong-eui | 3 | 1 | 3 | G Soeda | 4 | 6 | 5 | ||||||||||||||||||||
| 3 | G Soeda | 6 | 6 | L Saville | 77 | 3 | 4 | ||||||||||||||||||||
| 7 | T Ito | 77 | 6 | 7 | T Ito | 65 | 6 | 6 | |||||||||||||||||||
| WC | Yu Watanuki | 62 | 2 | 7 | T Ito | 6 | 6 | ||||||||||||||||||||
| WC | Yo Watanuki | 6 | 6 | WC | Yo Watanuki | 4 | 4 | ||||||||||||||||||||
 A Pavić | 3 | 3 | 7 | T Ito | 6 | 6 | |||||||||||||||||||||
| E Leshem | 3 | 3 | Q |  Y Shyla | 4 | 3 | |||||||||||||||||||||
| Q | Y Shyla | 6 | 6 | Q | Y Shyla | 66 | 6 | 6 | |||||||||||||||||||
| Q | K Takeuchi | 5 | 3 | 2 | Y Sugita | 78 | 4 | 4 | |||||||||||||||||||
| 2 | Y Sugita | 7 | 6 | ||||||||||||||||||||||||
Matthew Ebden was the defending champion but chose not to compete.
Matthew Ebden was the defending champion, however he chose not to participate.
James Duckworth is the defending champion, but chose not to participate.
Yoshihito Nishioka was the defending champion, but chose not to defend his title.
Yūichi Sugita won the title, defeating Stéphane Robert in the final 6–2, 1–6, 6–3.
Top seed John Millman won the title, defeating Taro Daniel in the final 6–1, 6–3.
Taro Daniel won the title, defeating Go Soeda in the final 4–6, 6–3, 6–3.
Yoshihito Nishioka won the title, defeating Alexander Kudryavtsev in the final 6–3, 6–4.
Three-time defending champion Kei Nishikori successfully defended his title, defeating Taylor Fritz in the final, 6–4, 6–4 to win the singles title at the 2016 Memphis Open. Notably, this was only Fritz' third career event on the ATP Tour.
Ivo Karlović was the defending champion, but lost to John-Patrick Smith in the first round.
Novak Djokovic was the defending champion and successfully defended his title winning for the 6th time, defeating Kei Nishikori in the final, 6–3 6–3. This was Djokovic's 3rd consecutive Indian Wells–Miami double. Novak also equaled Agassi's records of 3 consecutive Miami Masters titles and 6 overall Miami Masters titles, in addition to his record 28th Masters 1000 title.
Ruben Bemelmans was the defending champion, but decided not to defend his title.
Kevin Anderson was the defending champion, but lost in the second round to Jiří Veselý.
Matthew Ebden was the defending champion but lost in the second round to Marco Trungelliti.
Benjamin Mitchell was the defending champion but chose not to defend his title.
John Millman was the defending champion but chose not to defend his title.
David Goffin was the defending champion, but lost in the second round to Andy Murray.
Stéphane Robert was the defending champion but chose not to defend his title.
Tatsuma Ito was the defending champion but retired in the second round to Tseng Chun-hsin.
Daniil Medvedev won the title, defeating Reilly Opelka in the final, 6–4, 6–3. It was his fourth ATP Masters 1000 title and 12th career title.