| Doubles | |
|---|---|
| 2017 Knoxville Challenger | |
| Champions |  Leander Paes Purav Raja |
| Runners-up |  James Cerretani  John-Patrick Smith |
| Final score | 7–6(7–4), 7–6(7–4) |
Peter Polansky and Adil Shamasdin were the defending champions but chose not to defend their title.
Leander Paes and Purav Raja won the title after defeating James Cerretani and John-Patrick Smith 7–6(7–4), 7–6(7–4) in the final.
Leander Paes / Purav Raja (champions) James Cerretani / John-Patrick Smith (final)
Ruan Roelofse / 
Joe Salisbury (semifinals) Luke Bambridge / 
David O'Hare (first round)| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | L Paes P Raja | 6 | 6 | ||||||||||||||||||||||||
| K King B Klahn | 2 | 4 | 1 | L Paes P Raja | 7 | 6 | |||||||||||||||||||||
 D King M Mmoh | 0r | L Broady M Willis | 5 | 0 | |||||||||||||||||||||||
| L Broady M Willis | 3 | 1 | L Paes P Raja | 77 | 6 | ||||||||||||||||||||||
| 3 | R Roelofse J Salisbury | 78 | 7 | 3 | R Roelofse J Salisbury | 64 | 3 | ||||||||||||||||||||
 H Hach Verdugo D Novikov | 66 | 5 | 3 | R Roelofse J Salisbury | 6 | 6 | |||||||||||||||||||||
| M McDonald T Paul | 6 | 6 | M McDonald T Paul | 4 | 1 | ||||||||||||||||||||||
| WC | N Scholtz  Luis Valero | 3 | 4 | 1 | L Paes P Raja | 77 | 77 | ||||||||||||||||||||
| N Lammons A Lawson | 6 | 3 | [6] | 2 | J Cerretani J-P Smith | 64 | 64 | ||||||||||||||||||||
| WC | T Fritz Jared Hiltzik | 4 | 6 | [10] | WC | T Fritz J Hiltzik | 4 | 3 | |||||||||||||||||||
 R Maytín C Norrie | 710 | 6 | R Maytín C Norrie | 6 | 6 | ||||||||||||||||||||||
| 4 | L Bambridge D O'Hare | 68 | 3 | R Maytín C Norrie | 4 | 2 | |||||||||||||||||||||
| WC |  Timo Stodder Preston Touliatos | 3 | 3 | 2 | J Cerretani J-P Smith | 6 | 6 | ||||||||||||||||||||
| Jarryd Chaplin M Krueger | 6 | 6 | J Chaplin M Krueger | 2 | 5 | ||||||||||||||||||||||
| Q | D Köpfer M Moraing | 3 | 6 | [5] | 2 | J Cerretani J-P Smith | 6 | 7 | |||||||||||||||||||
| 2 | J Cerretani J-P Smith | 6 | 3 | [10] | |||||||||||||||||||||||
Jamie Delgado and Jonathan Marray were the defending champions of the 2012 Aegon Pro-Series but they decided not to participate together this year.
Delgado played alongside Ken Skupski, while Marray was involved in the 2012 ATP World Tour Finals.
James Cerretani and Adil Shamasdin won the final 6–4, 7–5 against Purav Raja and Divij Sharan.
Maxime Authom and Ruben Bemelmans are the defending champions, having won the event in 2012, but lost in the first round.
Sanchai and Sonchat Ratiwatana were the defending champions but lost in the final to Sam Groth and Leander Paes 4–6, 6–1, [10–7].
Gong Maoxin and Peng Hsien-yin were the defending champions, but Peng chose not to participate this year. Gong chose to partner with Yi.
Sergey Betov and Mikhail Elgin were the defending champions but chose to participate with different partners. Betov partnered Alexander Kudryavtsev but lost in the first round to Mirza Bašić and Blaž Kavčič. Elgin partnered Denis Istomin and won the title.
Gerard Granollers and Adrián Menéndez-Maceiras were the defending champions but only Menéndez-Maceiras defended his title, partnering John Paul Fruttero. Ménendez-Maceiras lost in the first round to Luca Margaroli and Hugo Nys.
Oliver Marach and Fabrice Martin were the defending champions, but Marach chose not to participate this year and Martin chose to compete in Doha instead.
Santiago González and Mate Pavić were the defending champions but only González chose to defend his title, partnering Artem Sitak. González lost in the first round to Marcelo Arévalo and Fabrício Neis.
Johan Brunström and Andreas Siljeström were the defending champions but chose not to defend their title.
Wesley Koolhof and Matwé Middelkoop were the defending champions but chose not to defend their title.
Sam Groth and Chris Guccione were the defending champions, but Guccione chose not to participate this year. Groth played alongside Leander Paes, but lost in the semifinals to Aisam-ul-Haq Qureshi and Rajeev Ram.
Sander Arends and Mateusz Kowalczyk were the defending champions but only Arends chose to defend his title, partnering Antonio Šančić.
Brian Baker and Sam Groth were the defending champions but chose not to defend their title.
Austin Krajicek and Tennys Sandgren were the defending champions but chose not to defend their title.
Jean-Julien Rojer and Horia Tecău were the defending champions, and successfully defended their title, defeating James Cerretani and Leander Paes in the final, 6–2, 7–6(7–2).
Leander Paes and Adil Shamasdin were the defending champions but chose not to defend their title.
Leander Paes and Purav Raja were the defending champions but only Paes chose to defend his title, partnering Miguel Ángel Reyes-Varela. Paes lost in the quarterfinals to Alex Lawson and Jackson Withrow.
Leander Paes and Purav Raja were the defending champions but chose not to defend their title.
Austin Krajicek and Jeevan Nedunchezhiyan were the defending champions but only Nedunchezhiyan chose to defend his title, partnering Purav Raja. Nedunchezhiyan lost in the semifinals to Marcus Daniell and Leander Paes.
Max Purcell and Luke Saville were the defending champions but chose not to defend their title.