Catherine Bellis was the defending champion, but decided not to participate this year.
Nina Bratchikova and Oksana Kalashnikova were the defending champions from the last time the event was held at Pune in 2012, but Bratchikova has been inactive in the sport since 2014. Kalashnikova played alongside Veronika Kudermetova, but lost in the quarterfinals to Beatrice Gumulya and Ana Veselinović.
Nicola Geuer and Anna Zaja were the defending champions, but Zaja chose not to participate. Geuer played alongside Cornelia Lister, but lost in the semifinals to Ysaline Bonaventure and Bibiane Schoofs.
Tímea Babos and Andrea Sestini Hlaváčková were the defending champions, but Babos chose not to participate and Sestini Hlaváčková chose to compete in Prague instead.
Katharina Gerlach and Julia Wachaczyk were the defending champions, but they lost to Amina Anshba and Albina Khabibulina in the quarterfinals.
The 2018 Advantage Cars Prague Open, also known as Advantage Cars Prague Open by Sport-Technik Bohemia for sponsorship reasons, was a professional tennis tournament played on outdoor clay courts. It was the 25th (ATP) and fourth (ITF) editions of the tournament and was part of the 2018 ATP Challenger Tour and also of the 2018 ITF Women's Circuit as 14th edition of the tournament. It took place in Prague, Czech Republic, on 23–29 July 2018.
The women's singles of the 2018 Advantage Cars Prague Open tournament was played on clay in Prague, Czech Republic.
Xenia Knoll and Amra Sadiković were the defending champions, but both players chose not to participate.
María Teresa Torró Flor was the defending champion, but chose not to participate.
Jeļena Ostapenko was the defending champion, but lost in the second round to Ekaterina Alexandrova.
Victoria Rodríguez and Bibiane Schoofs were the defending champions, but Rodríguez chose not to participate this year.
Ysaline Bonaventure and Bibiane Schoofs were the defending champions, but Bonaventure chose not to participate. Schoofs played alongside Olga Doroshina, but lost in the first round to Audrey Albié and Margot Yerolymos.
Olga Danilović was the defending champion, but chose not to participate.
Irina Bara and Valentina Ivakhnenko were the defending champions, but both players chose not to participate.
The women's doubles of the 2019 Advantage Cars Prague Open tournament was played on clay in Prague, Czech Republic.
This was the first edition of the tournament.
Wang Qiang was the defending champion, but lost in the first round to Peng Shuai.
Jeļena Ostapenko won the title, defeating defending champion Julia Görges in the final, 6–4, 6–1.
Cornelia Lister and Renata Voráčová were the defending champions, but they chose not to participate.
Natela Dzalamidze and Nina Stojanović were the defending champions, having won the previous edition in 2019, but Stojanović chose not to participate. Dzalamidze played alongside Paula Kania-Choduń but lost in the quarterfinals to Valentini Grammatikopoulou and Richèl Hogenkamp.
Cornelia Lister 
Nina Stojanović 
Bibiane Schoofs 
Kimberley Zimmermann 
