| Doubles | |
|---|---|
| 2021 Banja Luka Challenger | |
| Champions |  Antonio Šančić Nino Serdarušić |
| Runners-up | Ivan Sabanov Matej Sabanov |
| Score | 6–3, 6–3 |
Sadio Doumbia and Fabien Reboul were the defending champions [1] but chose not to defend their title.
Antonio Šančić and Nino Serdarušić won the title after defeating Ivan and Matej Sabanov 6–3, 6–3 in the final.
Ivan Sabanov / Matej Sabanov (final)
Manuel Guinard / 
Luca Margaroli (first round, withdrew)
Zdeněk Kolář / 
Vitaliy Sachko (semifinals)
James Cerretani / 
Fabian Fallert (semifinals)| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | I Sabanov M Sabanov | 6 | 6 | ||||||||||||||||||||||||
| WC |  Vladan Tadić M Topo | 2 | 2 | 1 | I Sabanov M Sabanov | 6 | 6 | ||||||||||||||||||||
V Kirkov  D Kuzmanov | 77 | 4 | [8] |  A Jecan DA Tomescu | 3 | 3 | |||||||||||||||||||||
| A Jecan Dan Alexandru Tomescu | 61 | 6 | [10] | 1 | I Sabanov M Sabanov | 2 | 6 | [10] | |||||||||||||||||||
| 3 | Z Kolář V Sachko | w/o | 3 | Z Kolář V Sachko | 6 | 3 | [6] | ||||||||||||||||||||
 C Gómez-Herrera P Krstin | 3 | Z Kolář V Sachko | 6 | 2 | [11] | ||||||||||||||||||||||
 M Bortolotti  M Cuevas | 6 | 6 | M Bortolotti M Cuevas | 3 | 6 | [9] | |||||||||||||||||||||
 M Eriksson DN Mădăraș | 1 | 2 | 1 | I Sabanov M Sabanov | 3 | 3 | |||||||||||||||||||||
 A Cozbinov  M Echargui | 7 | 6 | A Šančić N Serdarušić | 6 | 6 | ||||||||||||||||||||||
| N Milojević A Šetkić | 5 | 1 | A Cozbinov M Echargui | 64 | 5 | ||||||||||||||||||||||
| Davide Pozzi Alexander Weis | 4 | 63 | 4 | J Cerretani F Fallert | 77 | 7 | |||||||||||||||||||||
| 4 | J Cerretani F Fallert | 6 | 77 | 4 | J Cerretani F Fallert | 65 | 3 | ||||||||||||||||||||
| V Kopřiva David Poljak | 77 | 6 | A Šančić N Serdarušić | 77 | 6 | ||||||||||||||||||||||
| WC | Danijal Muminović Dražen Petrović | 65 | 3 | V Kopřiva D Poljak | 1 | 77 | [10] | ||||||||||||||||||||
| A Šančić N Serdarušić | w/o | A Šančić N Serdarušić | 6 | 64 | [12] | ||||||||||||||||||||||
| 2 | M Guinard L Margaroli | ||||||||||||||||||||||||||
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Ben McLachlan and Yasutaka Uchiyama were the defending champions but only Uchiyama chose to defend his title, partnering Kaito Uesugi. Uchiyama withdrew before his semifinal match.
Julian Ocleppo and Andrea Vavassori were the defending champions but only Vavassori chose to defend his title, partnering Andrea Pellegrino. Vavassori lost in the semifinals to Ivan and Matej Sabanov.
Andrej Martin and Hans Podlipnik Castillo were the defending champions but chose not to defend their title.
Kevin Krawietz and Andreas Mies were the defending champions but chose not to defend their title.
Simone Bolelli and Guillermo Durán were the defending champions but only Durán chose to defend his title, partnering Tim Sandkaulen. Durán lost in the quarterfinals to Szymon Walków and Jan Zieliński.
Guido Andreozzi and Andrés Molteni were the defending champions but only Molteni chose to defend his title, partnering Santiago González. Molteni successfully defended his title.
Andre Begemann and Albano Olivetti were the defending champions but chose not to defend their title.
Blaž Kavčič and Blaž Rola were the defending champions but chose not to defend their title.
Nathaniel Lammons and Jackson Withrow were the defending champions but only Withrow chose to defend his title, partnering Denys Molchanov. Withrow lost in the quarterfinals to Andrej Martin and Tristan-Samuel Weissborn.
Vitaliy Sachko and Dominic Stricker were the defending champions but chose not to defend their title.
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Orlando Luz and Rafael Matos were the defending champions but chose not to defend their title.
Zdeněk Kolář and Luis David Martínez were the defending champions but only Martínez chose to defend his title, partnering Fabien Reboul. Martínez lost in the semifinals to Ivan and Matej Sabanov.
Santiago González and Andrés Molteni were the defending champions but chose not to defend their title.
Alexander Erler and Lucas Miedler were the defending champions but lost in the final to Ivan and Matej Sabanov.
Alexander Erler and Lucas Miedler were the defending champions but lost in the semifinals to Reese Stalder and Petros Tsitsipas.
Marek Gengel and Adam Pavlásek were the defending champions but lost in the semifinals to Yuki Bhambri and Saketh Myneni.
Zdeněk Kolář and Andrea Vavassori were the defending champions but chose not to defend their title.
Alexander Erler and Lucas Miedler were the defending champions but chose not to defend their title.