| Doubles | |
|---|---|
| 2021 Città di Como Challenger | |
| Champions |  Rafael Matos Felipe Meligeni Alves |
| Runners-up |  Luis David Martínez  Andrea Vavassori |
| Score | 6–7(2–7), 6–4, [10–6] |
Andre Begemann and Florin Mergea were the defending champions [1] but chose not to defend their title.
Rafael Matos and Felipe Meligeni Alves won the title after defeating Luis David Martínez and Andrea Vavassori 6–7(2–7), 6–4, [10–6] in the final.
Rafael Matos / Felipe Meligeni Alves (champions) Luis David Martínez / Andrea Vavassori (final)
Ivan Sabanov / Matej Sabanov (first round)
Andre Begemann / 
Albano Olivetti (first round)| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | R Matos F Meligeni Alves | 6 | 6 | ||||||||||||||||||||||||
| WC | Federico Iannaccone A Motti | 3 | 1 | 1 | R Matos F Meligeni Alves | w/o | |||||||||||||||||||||
| Alt |  Mariano Kestelboim C Ugo Carabelli | 6 | 77 | Alt | M Kestelboim C Ugo Carabelli | ||||||||||||||||||||||
| S Doumbia F Reboul | 4 | 62 | 1 | R Matos F Meligeni Alves | 7 | 6 | |||||||||||||||||||||
| 3 | I Sabanov M Sabanov | 7 | 2 | [7] |  A Erler L Miedler | 5 | 2 | ||||||||||||||||||||
M Bortolotti  M Cuevas | 5 | 6 | [10] | M Bortolotti M Cuevas | 6 | 4 | [4] | ||||||||||||||||||||
| F Baldi J Ocleppo | 2 | 3 | A Erler L Miedler | 4 | 6 | [10] | |||||||||||||||||||||
| A Erler L Miedler | 6 | 6 | 1 | R Matos F Meligeni Alves | 62 | 6 | [10] | ||||||||||||||||||||
D Brown  A Martin | 6 | 6 | 2 | LD Martínez A Vavassori | 77 | 4 | [6] | ||||||||||||||||||||
| WC | Niccolò Ciavarella Daniele Minighini | 0 | 1 | D Brown A Martin | 4 | 6 | [10] | ||||||||||||||||||||
 M-A Hüsler L Margaroli | 3 | 6 | [10] | M-A Hüsler L Margaroli | 6 | 3 | [7] | ||||||||||||||||||||
| 4 | A Begemann A Olivetti | 6 | 1 | [5] | D Brown A Martin | 3 | 4 | ||||||||||||||||||||
| G Blancaneaux T Lamasine | 1 | 3 | 2 | LD Martínez A Vavassori | 6 | 6 | |||||||||||||||||||||
| WC | F Forti G Zeppieri | 6 | 6 | WC | F Forti G Zeppieri | 4 | 4 | ||||||||||||||||||||
| J Menezes M Pucinelli de Almeida | 2 | LD Martínez A Vavassori | 6 | 6 | |||||||||||||||||||||||
| 2 | LD Martínez A Vavassori | w/o | |||||||||||||||||||||||||
Andrés Artuñedo and David Pérez Sanz were the defending champions but only Artuñedo chose to defend his title, partnering Sergio Martos Gornés. Artuñedo lost in the first round to Andreas Siljeström and Andrea Vavassori.
Hugo Dellien and Guillermo Durán were the defending champions but only Dellien chose to defend his title, partnering Federico Zeballos. Dellien and Zeballos withdrew before their quarterfinal match.
Guillermo Durán and Roberto Quiroz were the defending champions but only Quiroz chose to defend his title, partnering Yannick Hanfmann. Quiroz lost in the first round to Luis David Martínez and Felipe Meligeni Alves.
Guido Andreozzi and Guillermo Durán were the defending champions but chose not to defend their title.
Sadio Doumbia and Fabien Reboul were the defending champions but chose not to defend their title.
Ariel Behar and Gonzalo Escobar were the defending champions but only Escobar chose to defend his title, partnering Diego Hidalgo. Escobar lost in the first round to Íñigo Cervantes and Oriol Roca Batalla.
Orlando Luz and Rafael Matos were the defending champions but only Matos chose to defend his title, partnering João Menezes. Matos withdrew from the tournament before his quarterfinal match.
Franco Agamenone and Fernando Romboli were the defending champions but chose not to defend their title.
Lloyd Glasspool and Matt Reid were the defending champions but chose not to defend their title.
Evan King and Julian Lenz were the defending champions but only King chose to defend his title, partnering Jan Zieliński. King lost in the first round to Franco Agamenone and Omar Giacalone.
Radu Albot and Enrique López Pérez were the defending champions but chose not to defend their title.
This was the first edition of the tournament.
Luis David Martínez and Gonçalo Oliveira were the defending champions but lost in the semifinals to Evan King and Max Schnur.
Sadio Doumbia and Fabien Reboul were the defending champions but chose not to defend their title.
Luis David Martínez and Felipe Meligeni Alves were the defending champions but chose to defend their title with different partners. Martínez partnered Fernando Romboli but lost in the semifinals to Nicolás Barrientos and Alejandro Gómez. Meligeni Alves partnered Rafael Matos but withdrew before the final due to a positive test for COVID-19.
Santiago González and Andrés Molteni defeated Andrej Martin and Tristan-Samuel Weissborn in the final, 7–5, 6–3, to win the doubles tennis title at the 2022 Córdoba Open. It was their third career ATP Tour doubles title together. As alternates, Martin and Weissborn were competing in their second event as a team.
Simone Bolelli and Máximo González were the defending champions but Bolelli chose not to participate. González was scheduled to partner Nicolás Jarry, but Jarry withdrew with a right elbow injury before their first round match.
Santiago González and Andrés Molteni were the defending champions but chose not to defend their title.
Rafael Matos and Felipe Meligeni Alves were the defending champions but only Meligeni Alves chose to defend his title, partnering Matheus Pucinelli de Almeida. They withdrew before their first round match.
Andrea Pellegrino and Andrea Vavassori defeated Thiago Seyboth Wild and Matías Soto in the final, 6–4, 3–6, [12–10] to win the doubles tennis title at the 2023 Chile Open.