| Doubles | |
|---|---|
| 2021 LTP Charleston Pro Tennis II | |
| Champions |  Fanny Stollár  Aldila Sutjiadi |
| Runners-up |  Rasheeda McAdoo Peyton Stearns |
| Score | 6–0, 6–4 |
Anna Danilina and Ingrid Neel were the defending champions, having won the previous edition in 2019, [1] but both players chose not to participate.
Fanny Stollár and Aldila Sutjiadi won the title, defeating Rasheeda McAdoo and Peyton Stearns in the final, 6–0, 6–4.
Fanny Stollár / Aldila Sutjiadi (champions) Quinn Gleason / Maria Sanchez (first round)
Hsu Chieh-yu / 
Erika Sema (first round) Kyōka Okamura / 
Conny Perrin (quarterfinals)| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | F Stollár A Sutjiadi | 6 | 6 | ||||||||||||||||||||||||
| WC |  K Jokić  J Tilbürger | 1 | 4 | 1 | F Stollár A Sutjiadi | 6 | 6 | ||||||||||||||||||||
 V Rodríguez AS Sánchez | 2 | 6 | [7] | S Chang E Navarro | 0 | 4 | |||||||||||||||||||||
| S Chang E Navarro | 6 | 3 | [10] | 1 | F Stollár A Sutjiadi | 6 | 6 | ||||||||||||||||||||
| 3 | C-y Hsu E Sema | 710 | 3 | [6] | F Contreras M Zacarías | 2 | 2 | ||||||||||||||||||||
| F Contreras M Zacarías | 68 | 6 | [10] | F Contreras M Zacarías | 6 | 6 | |||||||||||||||||||||
| Alt | E Davis N Hanatani | 6 | 7 | Alt | E Davis N Hanatani | 3 | 2 | ||||||||||||||||||||
| WC | P Charney T Ng | 4 | 5 | 1 | F Stollár A Sutjiadi | 6 | 6 | ||||||||||||||||||||
| A Parks A Zhu | 1 | 4 | R McAdoo P Stearns | 0 | 4 | ||||||||||||||||||||||
| R McAdoo P Stearns | 6 | 6 | R McAdoo P Stearns | 6 | 7 | ||||||||||||||||||||||
| A Zamarripa M Zamarripa | 3 | 6 | [6] | 4 | K Okamura C Perrin | 3 | 5 | ||||||||||||||||||||
| 4 | K Okamura C Perrin | 6 | 0 | [10] | R McAdoo P Stearns | 6 | 6 | ||||||||||||||||||||
| WC | G Pielet K Stewart | 64 | 5 | D Ivanova  G Topalova | 3 | 2 | |||||||||||||||||||||
| D Ivanova G Topalova | 77 | 7 | D Ivanova G Topalova | 2 | 6 | [11] | |||||||||||||||||||||
M Mateas  D Papamichail | 6 | 6 | M Mateas D Papamichail | 6 | 3 | [9] | |||||||||||||||||||||
| 2 | Q Gleason M Sanchez | 3 | 4 | ||||||||||||||||||||||||
Océane Dodin was the defending champion, but withdrew from her second round match due to dizziness.
Anett Kontaveit was the defending champion, but lost in the first round to Veronika Kudermetova.
Kateryna Bondarenko was the defending champion, but chose not to participate.
Roberta Vinci was the champion the last time the tournament was held in 2013, but she has since retired from professional tennis.
Wang Xinyu and You Xiaodi were the defending champions, but Wang chose to compete at the 2019 US Open instead. You partnered alongside Chihiro Muramatsu, but lost in the first round to Eudice Chong and Aldila Sutjiadi.
Luksika Kumkhum was the defending champion, but chose not to participate.
Asia Muhammad and Taylor Townsend were the defending champions, having won the last edition in 2019, however both players chose not to participate.
The 2021 LTP Charleston Pro Tennis II was a professional women's tennis tournament played on outdoor clay courts. It was the sixth edition of the tournament which was part of the 2021 ITF Women's World Tennis Tour. It took place in Charleston, South Carolina, United States between 21 and 27 June 2021.
This was the first edition of the tournament.
Shelby Rogers was the defending champion, but chose not to participate.
Caroline Dolehide and Maria Sanchez were the defending champions but chose not to participate.
Cara Black and Arina Rodionova were the defending champions, having won the previous edition in 2012. However Black retired from professional tennis in 2015 and Rodionova chose to compete at the 2022 Melbourne Summer Set instead.
Paige Hourigan and Astra Sharma were the defending champions having won the previous edition in 2019, however both players chose not to participate.
Astra Sharma and Aldila Sutjiadi defeated Emina Bektas and Tara Moore in the final, 4–6, 6–4, [11–9], to win the doubles tennis title at the 2022 Copa Colsanitas. The win earned Sharma her second Copa Colsanitas doubles title after first winning in 2019, and Sutjiadi her first career Women's Tennis Association (WTA) title.
Fanny Stollár and Aldila Sutjiadi were the defending champions but chose not to participate.
Mihaela Buzărnescu and Fanny Stollár were the defending champions, but only Stollár chose to defend her title, partnering Tímea Babos. Stollár lost in the semifinals to Katarzyna Piter and Kimberley Zimmermann.
Hayley Carter and Luisa Stefani were the defending champions but chose not to participate.
This was the first edition of the tournament as a WTA 125 tournament.
Arianne Hartono and Olivia Tjandramulia were the defending champions, but chose not to participate.
Asia Muhammad and Taylor Townsend were the reigning champions from 2020, when the event was last held, but chose to compete in Adelaide instead.