| Singles | |
|---|---|
| 2021 LTP Charleston Pro Tennis | |
| Champion |  Claire Liu |
| Runner-up | Madison Brengle |
| Final score | 6–2, 7–6(8–6) |
Mayar Sherif was the defending champion [1] but lost to Claire Liu in the second round.
Liu went on to win the title, defeating Madison Brengle in the final, 6–2, 7–6(8–6).
Madison Brengle (Final) Caty McNally (First round)
Mayar Sherif (Second round) Kristie Ahn (First round)
Irina Bara (Second round)
Renata Zarazúa (Quarterfinals)
Olga Govortsova (Quarterfinals)
Wang Xinyu (First round)| Semifinals | Final | ||||||||||||
| 1 | Madison Brengle | 78 | 6 | ||||||||||
 Magdalena Fręch | 66 | 3 | |||||||||||
| 1 | Madison Brengle | 2 | 66 | ||||||||||
| SE | Claire Liu | 6 | 78 | ||||||||||
| SE | Claire Liu | 4 | 6 | 6 | |||||||||
 Harriet Dart | 6 | 3 | 3 | ||||||||||
| First Round | Second Round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | M Brengle | 6 | 6 | ||||||||||||||||||||||||
| W Osuigwe | 1 | 0 | 1 | M Brengle | 7 | 6 | |||||||||||||||||||||
| F Di Lorenzo | 1 | 2 |  V Cepede Royg | 5 | 2 | ||||||||||||||||||||||
| V Cepede Royg | 6 | 6 | 1 | M Brengle | 7 | 77 | |||||||||||||||||||||
 S Sanders | 6 | 6 | WC | K Volynets | 5 | 63 | |||||||||||||||||||||
| G Talabă | 0 | 1 | S Sanders | 2 | 0 | ||||||||||||||||||||||
| WC | K Volynets | 2 | 6 | 6 | WC | K Volynets | 6 | 6 | |||||||||||||||||||
| 8 | Xin Wang | 6 | 3 | 2 | 1 | M Brengle | 78 | 6 | |||||||||||||||||||
| 4 | K Ahn | 4 | 3 | M Fręch | 66 | 3 | |||||||||||||||||||||
| M Fręch | 6 | 6 | M Fręch | 4 | 6 | 6 | |||||||||||||||||||||
| WC | K Shaffer | 3 | 1 | Q | V Duval | 6 | 4 | 1 | |||||||||||||||||||
| Q | V Duval | 6 | 6 | M Fręch | 6 | 6 | |||||||||||||||||||||
| Q |  E Hozumi | 4 | 6 | 1 | 6 | R Zarazúa | 4 | 1 | |||||||||||||||||||
| G Min | 6 | 1 | 6 | G Min | 2 | 1 | |||||||||||||||||||||
| H Baptiste | 4 | 1 | 6 | R Zarazúa | 6 | 6 | |||||||||||||||||||||
| 6 | R Zarazúa | 6 | 6 | ||||||||||||||||||||||||
| First Round | Second Round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 5 | I Bara | 4 | 6 | 6 | |||||||||||||||||||||||
| A Kiick | 6 | 3 | 0 | 5 | I Bara | 6 | 64 | 3 | |||||||||||||||||||
| Q |  A Anshba | 7 | 3 | 0 | Q | J Loeb | 4 | 77 | 6 | ||||||||||||||||||
| Q | J Loeb | 5 | 6 | 6 | Q | J Loeb | 2 | 4 | |||||||||||||||||||
| SE | C Liu | 6 | 6 | SE | C Liu | 6 | 6 | ||||||||||||||||||||
| WC | A Parks | 4 | 4 | SE | C Liu | 6 | 6 | ||||||||||||||||||||
| Q | U Radwańska | 4 | 3 | 3 | M Sherif | 3 | 0 | ||||||||||||||||||||
| 3 | M Sherif | 6 | 6 | SE | C Liu | 4 | 6 | 6 | |||||||||||||||||||
| 7 | O Govortsova | 6 | 7 | H Dart | 6 | 3 | 3 | ||||||||||||||||||||
| Q |  A Krunić | 3 | 5 | 7 | O Govortsova | 7 | 0 | 6 | |||||||||||||||||||
| C Dolehide | 1 | 6 | 4 | Q |  A Sutjiadi | 5 | 6 | 4 | |||||||||||||||||||
| Q | A Sutjiadi | 6 | 2 | 6 | 7 | O Govortsova | 77 | 3 | 4 | ||||||||||||||||||
| Q |  A Hartono | 1 | 6 | 4 | H Dart | 65 | 6 | 6 | |||||||||||||||||||
| Ar Rodionova | 6 | 2 | 6 | Ar Rodionova | 63 | 6 | 1 | ||||||||||||||||||||
| H Dart | 65 | 6 | 6 | H Dart | 77 | 4 | 6 | ||||||||||||||||||||
| 2/WC | C McNally | 77 | 4 | 3 | |||||||||||||||||||||||
Anastasia Pavlyuchenkova was the defending champion and successfully defended her title, defeating Madison Brengle in the final, 7–6(8–6), 7–6(7–3).
Caroline Wozniacki was the defending champion but did not complete in the Juniors this year.
Nadia Petrova won the first edition of this tournament, defeating Shahar Pe'er 7–5, 6–2 in the final.
Garbiñe Muguruza was the defending champion heading into the tournament but chose to compete at the Sydney tennis event instead of Hobart. In the final, it was unseeded Brit Heather Watson who defeated the American qualifier in Madison Brengle, 6–3, 6–4 to record her second WTA title.
Caroline Wozniacki was the defending champion and successfully defended her title, defeating Anastasia Pavlyuchenkova in the final, 6–0, 7–5. This marked Wozniacki's first title of 2017 and snapped a six-match losing streak in tournament finals.
Danielle Collins was the defending champion, but chose not to participate as she was still competing at the Australian Open.
Madison Brengle was the defending champion but lost to Caty McNally in the quarterfinals.
Taylor Townsend was the defending champion, but lost in the first round to Sesil Karatantcheva.
Mariana Duque Mariño was the defending champion, but she had retired from professional tennis earlier in the year.
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This was the first edition of the tournament.
Xu Shilin was the defending champion but chose to participate at the 2019 Shenzhen Longhua Open instead.
This was the first edition of the tournament.
Taylor Townsend was the defending champion, but chose not to participate as she is on maternity leave.
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Elina Svitolina was the defending champion, but decided not to participate.
This was the first edition of the tournament, organised with a single-year license in 2021.
Whitney Osuigwe was the defending champion, having won the last edition in 2019 but retired in the first round against Arianne Hartono.
Lauren Davis was the defending champion having won the previous edition in 2019, but chose not to participate.
Varvara Gracheva was the defending champion but chose to compete at Wimbledon instead.