| Doubles | |
|---|---|
| 2021 Meerbusch Challenger | |
| Champions |  Szymon Walków Jan Zieliński |
| Runners-up |  Dustin Brown  Robin Haase |
| Score | 6–3, 6–1 |
Andre Begemann and Florin Mergea were the defending champions [1] but only Begemann chose to defend his title, partnering Albano Olivetti. Begemann lost in the first round to Jesper de Jong and Bart Stevens.
Szymon Walków and Jan Zieliński won the title after defeating Dustin Brown and Robin Haase 6–3, 6–1 in the final.
Denys Molchanov / 
Aleksandr Nedovyesov (quarterfinals)
Ivan Sabanov / Matej Sabanov (quarterfinals) Andre Begemann / 
Albano Olivetti (first round) Dustin Brown / Robin Haase (final)| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | D Molchanov A Nedovyesov | 77 | 6 | ||||||||||||||||||||||||
| Alt |  L Klein  J Pospíšil | 65 | 4 | 1 | D Molchanov A Nedovyesov | 64 | 5 | ||||||||||||||||||||
A Šančić  A Sitak | 7 | 6 | A Šančić A Sitak | 77 | 7 | ||||||||||||||||||||||
| WC | F Fallert J Härteis | 5 | 4 | A Šančić A Sitak | 4 | 4 | |||||||||||||||||||||
| 4 | D Brown R Haase | 6 | 6 | 4 | D Brown R Haase | 6 | 6 | ||||||||||||||||||||
 H Hach Verdugo MÁ Reyes-Varela | 4 | 2 | 4 | D Brown R Haase | 6 | 6 | |||||||||||||||||||||
 R Gonzales  H Johnson | 77 | 6 | R Gonzales H Johnson | 0 | 4 | ||||||||||||||||||||||
| WC | Constantin Schmitz P Tsitsipas | 62 | 1 | 4 | D Brown R Haase | 3 | 1 | ||||||||||||||||||||
D Ajduković  N Fatić | 6 | 6 | S Walków J Zieliński | 6 | 6 | ||||||||||||||||||||||
| WC |  A Merino  S Mochizuki | 4 | 1 | D Ajduković N Fatić | 0 | 2 | |||||||||||||||||||||
| J de Jong B Stevens | 6 | 7 | J de Jong B Stevens | 6 | 6 | ||||||||||||||||||||||
| 3 | A Begemann A Olivetti | 4 | 5 | J de Jong B Stevens | 2 | 77 | [9] | ||||||||||||||||||||
 JP Ficovich N Kicker | 3 | 2 | S Walków J Zieliński | 6 | 62 | [11] | |||||||||||||||||||||
| S Walków J Zieliński | 6 | 6 | S Walków J Zieliński | 77 | 6 | ||||||||||||||||||||||
 B Bobrov R Safiullin | 2 | 66 | 2 | I Sabanov M Sabanov | 65 | 4 | |||||||||||||||||||||
| 2 | I Sabanov M Sabanov | 6 | 78 | ||||||||||||||||||||||||
Andre Begemann and Alexander Kudryavtsev were the defending champions but Kudryavtsev decided not to participate.
Begemann played alongside Martin Emmrich.
James Cerretani and Adil Shamasdin won the title, defeating Tomasz Bednarek and Andreas Siljeström 6–3, 2–6, [10–4] in the final.
Jamie Murray and John Peers were the defending champions, but lost in the quarterfinals to Facundo Bagnis and Federico Delbonis.
Andre Begemann and Robin Haase won the title, defeating Rameez Junaid and Michal Mertiňák in the final, 6–3, 6–4.
Martin Emmrich and Christopher Kas were the defending champions, but chose not to participate together. Emmrich played alongside Lukáš Rosol, but lost to Daniele Bracciali and Andrey Golubev in the semifinals. Kas teamed up with Philipp Kohlschreiber, but lost to Henri Kontinen and Jarkko Nieminen in the quarterfinals.
Kontinen and Nieminen won the title, defeating Bracciali and Golubev in the final, 6–1, 6–4.
Johan Brunström and Frederik Nielsen were the defending champions, but Nielsen chose not to participate. Brunström played alongside Nicholas Monroe, but lost in the first round to Roberto Bautista Agut and Stan Wawrinka.
Lu Yen-hsun and Jonathan Marray won the title, defeating Raven Klaasen and Leander Paes in the final, 6–3, 7-6(7–4).
Julien Benneteau and Édouard Roger-Vasselin were the defending champions, but did not participate due to Benneteau's injury.
Jean-Julien Rojer and Horia Tecău were the defending champions, but chose not to participate this year.
Rameez Junaid and Adil Shamasdin won the title, defeating Rohan Bopanna and Florin Mergea in the final, 3–6, 6–2, [10–7].
Hans Podlipnik Castillo and Andrei Vasilevski were the defending champions but chose not to defend their title.
Dominic Inglot and Franko Škugor were the defending champions, but Škugor chose to compete in Barcelona instead. Inglot played alongside Rohan Bopanna, but lost in the quarterfinals to Andre Begemann and Ernests Gulbis.
Robert Galloway and Nathaniel Lammons were the defending champions but chose not to defend their title.
James Cerretani and Maxime Cressy were the defending champions but chose to compete with different partners. Cerretani partnered Dustin Brown but lost in the semifinals to Lloyd Glasspool and Alex Lawson. Cressy partnered Albano Olivetti but lost in the first round to Marc-Andrea Hüsler and Kamil Majchrzak.
Nikola Ćaćić and Antonio Šančić were the defending champions but chose not to defend their title.
Andre Begemann and Daniel Masur were the defending champions but chose to defend their title with different partners. Begemann partnered Albano Olivetti but lost in the semifinals to Lloyd Glasspool and Harri Heliövaara. Masur partnered Julian Lenz but lost in the semifinals to Zdeněk Kolář and Andrea Vavassori.
Simone Bolelli and Guillermo Durán were the defending champions but only Durán chose to defend his title, partnering Tim Sandkaulen. Durán lost in the quarterfinals to Szymon Walków and Jan Zieliński.
Sander Gillé and Joran Vliegen were the reigning champions from when the tournament was last held in 2019, but chose not to defend their title.
This was the first edition of the tournament.
Andre Begemann and Florin Mergea were the defending champions but chose not to defend their title.
Andre Begemann and Albano Olivetti were the defending champions but chose not to defend their title.
Ivan and Matej Sabanov were the defending champions but chose not to defend their title.
Szymon Walków and Jan Zieliński were the defending champions but chose not to defend their title.
Denys Molchanov and David Vega Hernández were the defending champions but chose not to defend their title.