Cristina Bucșa and María Fernanda Herazo were the defending champions, but Herazo chose not to participate. Bucșa partnered alongside Diāna Marcinkēviča, but lost in the quarterfinals to Lou Brouleau and Ioana Loredana Roșca.
Irina Khromacheva and Nina Stojanović were the defending champions, but chose not to participate.
Lucie Hradecká and Andreja Klepač were the defending champions but Hradecká chose not to participate. Klepač partnered Kirsten Flipkens, but lost in the quarterfinals to Ekaterine Gorgodze and Ankita Raina.
The 2021 Bol Open was a professional tennis tournament played on outdoor clay courts. It was the fifteenth edition of the tournament and part of the 2021 WTA 125K series. The tournament could not be held in 2020 due to Covid-19 pandemic. It took place in Bol, Croatia, from 7 to 12 June 2021.
Tamara Zidanšek was the two-time defending champion, having won the last edition in 2019, however she was unable to defend her title as she was still competing at the 2021 French Open, reaching the semi-final of the Grand Slam.
Timea Bacsinszky and Mandy Minella were the defending champions, having won the previous edition in 2019, but chose not to participate.
Lara Arruabarrena and Renata Voráčová were the defending champions having won the previous edition in 2019, but chose not to participate.
This was the first edition of the tournament.
This was the first edition of the tournament.
Varvara Gracheva was the defending champion but chose to participate at the 2021 J&T Banka Ostrava Open instead.
Irina Bara and Rebeka Masarova were the defending champions but lost in the semifinals to Aliona Bolsova and Andrea Gámiz.
This was the first edition of the tournament since 1987.
This was the first edition of the women's event.
Laura Siegemund and Vera Zvonareva defeated Alicia Barnett and Olivia Nicholls in the final, 7–5, 6–1 to win the doubles tennis title at the 2022 WTA Lyon Open.
This was the first edition of the tournament.
Elina Avanesyan was the defending champion but chose not to participate.
Kirsten Flipkens and Laura Siegemund defeated Kamilla Rakhimova and Yana Sizikova in the final, 6–3, 7–5 to win the doubles tennis title at the 2022 Transylvania Open.
Irina Khromacheva and Arina Rodionova were the defending champions but chose not to participate.
Aliona Bolsova and Andrea Gámiz were the defending champions but Gámiz chose to compete at the 2022 Montevideo Open instead. Bolsova partnered alongside Rebeka Masarova but lost in the quarterfinals to Irina Khromacheva and Iryna Shymanovich.
Irina Bara and Ekaterine Gorgodze were the defending champions, but chose to participate with different partners. Bara played alongside Réka Luca Jani but lost in the quarterfinals to Andrea Gámiz and Eva Vedder. Gorgodze played alongside Tímea Babos but lost in the first round to Amina Anshba and Darya Astakhova.
Aliona Bolsova 
Alexandra Panova 
Arantxa Rus 
