| Doubles | |
|---|---|
| 2022 Columbus Challenger II | |
| Champions |  Julian Cash Henry Patten |
| Runners-up | Charles Broom  Constantin Frantzen |
| Score | 6–2, 7–5 |
Tennys Sandgren and Mikael Torpegaard were the defending champions [1] but chose not to defend their title.
Julian Cash and Henry Patten won the title after defeating Charles Broom and Constantin Frantzen 6–2, 7–5 in the final.
Julian Cash / Henry Patten (champions)
Nicolás Mejía / 
Roberto Quiroz (first round)
Enzo Couacaud / 
Andrew Harris (quarterfinals)
Benjamin Lock / Courtney John Lock (first round)| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | J Cash H Patten | 6 | 6 | ||||||||||||||||||||||||
 Jack Anthrop Alexander Bernard | 4 | 2 | A McHugh R Stalder | 2 | 3 | ||||||||||||||||||||||
| A McHugh R Stalder | 6 | 6 | 1 | J Cash H Patten | 6 | 6 | |||||||||||||||||||||
| 3 | E Couacaud A Harris | 6 | 77 | C Kingsley J Tracy | 2 | 2 | |||||||||||||||||||||
| Roy Smith D Young | 4 | 61 | 3 | E Couacaud A Harris | 1 | 4 | |||||||||||||||||||||
| C Kingsley J Tracy | 6 | 6 | |||||||||||||||||||||||||
| 1 | J Cash H Patten | 6 | 7 | ||||||||||||||||||||||||
 J Boulais  J Trotter | 5 | 6 | [10] | C Broom C Frantzen | 2 | 5 | |||||||||||||||||||||
| WC | Preston Stearns Reece Yakubov | 7 | 2 | [4] | J Boulais J Trotter | 77 | 63 | [12] | |||||||||||||||||||
| C Broom C Frantzen | 4 | 6 | [10] | C Broom C Frantzen | 65 | 77 | [14] | ||||||||||||||||||||
| 4 | B Lock CJ Lock | 6 | 3 | [2] | C Broom C Frantzen | 6 | 6 | ||||||||||||||||||||
 D Glinka Karl Kiur Saar | 6 | 7 | WC | R Cash  M Vocel | 4 | 4 | |||||||||||||||||||||
| N Chappell E Zhu | 4 | 5 | D Glinka KK Saar | 1 | 611 | ||||||||||||||||||||||
| WC | R Cash Matěj Vocel | 6 | 6 | WC | R Cash M Vocel | 6 | 713 | ||||||||||||||||||||
| 2 | N Mejía R Quiroz | 3 | 1 | ||||||||||||||||||||||||
Marcel Granollers and Ben McLachlan were the defending champions but chose not to defend their title.
Santiago González and Aisam-ul-Haq Qureshi were the defending champions but chose not to defend their title.
Liam Draxl and Stefan Kozlov were the defending champions but chose not to defend their title.
André Göransson and Sem Verbeek were the defending champions but chose not to defend their title.
Robert Galloway and Roberto Maytín were the defending champions but chose not to defend their title.
Darian King and Peter Polansky were the defending champions but chose not to defend their title.
William Blumberg and Max Schnur were the defending champions but only Blumberg chose to defend his title, partnering Ben Shelton. Blumberg lost in the semifinals to Constantin Frantzen and Reese Stalder.
William Blumberg and Max Schnur were the defending champions but chose to defend their title with different partners. Blumberg partnered Jackson Withrow but lost in the first round to Anirudh Chandrasekar and Vijay Sundar Prashanth. Schnur partnered Treat Huey but lost in the first round to Julian Cash and Henry Patten.
Malek Jaziri and Blaž Rola were the defending champions but chose not to defend their title.
Manuel Guinard and Arthur Rinderknech were the defending champions but chose not to defend their title.
Karol Drzewiecki and Szymon Walków were the defending champions but only Walków chose to defend his title, partnering Łukasz Kubot. Walków lost in the semifinals to Julian Cash and Henry Patten.
Nuno Borges and Francisco Cabral were the defending champions but lost in the final to Julian Cash and Henry Patten.
Julian Cash and Henry Patten were the defending champions but withdrew from their semifinal match against Liam Broady and Jonny O'Mara.
Julian Cash and Henry Patten were the defending champions but chose not to defend their title.
Julian Cash and Henry Patten were the defending champions but chose not to defend their title.
Altuğ Çelikbilek and Dmitry Popko were the defending champions but chose not to defend their title.
Julian Cash and Henry Patten were the defending champions but chose not to defend their title.
Julian Cash and Henry Patten were the defending champions but chose not to defend their title.
Julian Cash and Henry Patten were the defending champions but chose not to defend their title.
Julian Cash and Henry Patten were the defending champions but chose not to defend their title.