| Men's singles | |
|---|---|
| 2022 Lisboa Belém Open | |
| Champion |  Marco Cecchinato |
| Runner-up |  Luca Van Assche |
| Score | 6–3, 6–3 |
Dmitry Popko was the defending champion [1] but chose not to defend his title.
Marco Cecchinato won the title after defeating Luca Van Assche 6–3, 6–3 in the final.
Pedro Cachin (first round)
Carlos Taberner (quarterfinals) Francesco Passaro (second round)
Filip Misolic (semifinals, retired) Marco Cecchinato (champion) Franco Agamenone (second round) Alexandre Müller (quarterfinals) Manuel Guinard (first round)| Semifinals | Final | ||||||||||||
| Q | Luca Van Assche | 6 | 0 | ||||||||||
| 4 | Filip Misolic | 1 | 0r | ||||||||||
| Q | Luca Van Assche | 3 | 3 | ||||||||||
| 5 | Marco Cecchinato | 6 | 6 | ||||||||||
| Alt |  Timofey Skatov | 5 | 62 | ||||||||||
| 5 | Marco Cecchinato | 7 | 77 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | P Cachin | 2 | 77 | 64 | |||||||||||||||||||||||
 G Elias | 6 | 63 | 77 | G Elias | 3 | 2 | |||||||||||||||||||||
| R Bonadio | 6 | 1 | 64 | Q | L Van Assche | 6 | 6 | ||||||||||||||||||||
| Q | L Van Assche | 4 | 6 | 77 | Q | L Van Assche | 6 | 7 | |||||||||||||||||||
 Z Kolář | 1 | 6 | 3 | 7 | A Müller | 4 | 5 | ||||||||||||||||||||
| Q |  D Ajduković | 6 | 4 | 6 | Q | D Ajduković | 1 | 3 | |||||||||||||||||||
| WC | J Domingues | 77 | 2 | 3 | 7 | A Müller | 6 | 6 | |||||||||||||||||||
| 7 | A Müller | 65 | 6 | 6 | Q | L Van Assche | 6 | 0 | |||||||||||||||||||
| 4 | F Misolic | 7 | 6 | 4 | F Misolic | 1 | 0r | ||||||||||||||||||||
| A Pellegrino | 5 | 2 | 4 | F Misolic | 2 | 6 | 6 | ||||||||||||||||||||
| WC | P Sousa | 6 | 4 | 1 | V Kopřiva | 6 | 2 | 3 | |||||||||||||||||||
| V Kopřiva | 4 | 6 | 6 | 4 | F Misolic | 6 | 6 | ||||||||||||||||||||
| Q |  Jeremy Jahn | 5 | 4 | G Zeppieri | 4 | 4 | |||||||||||||||||||||
| G Zeppieri | 7 | 6 | G Zeppieri | 4 | 6 | 6 | |||||||||||||||||||||
| SE |  N Moreno de Alboran | 4 | 5 | 6 | F Agamenone | 6 | 0 | 1 | |||||||||||||||||||
| 6 | F Agamenone | 6 | 7 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 8 | M Guinard | 3 | 64 | ||||||||||||||||||||||||
| GM Moroni | 6 | 77 | GM Moroni | 4 | 3r | ||||||||||||||||||||||
| B Paire | 7 | 6 | B Paire | 6 | 4 | ||||||||||||||||||||||
| Q | G Oliveira | 5 | 4 | B Paire | 4 | 6 | 5 | ||||||||||||||||||||
| Q | O Roca Batalla | 68 | 65 | Alt | T Skatov | 6 | 2 | 7 | |||||||||||||||||||
| Alt | T Skatov | 710 | 77 | Alt | T Skatov | 6 | 5 | 6 | |||||||||||||||||||
| WC | F Ferreira Silva | 4 | 6 | 1 | 3 | F Passaro | 1 | 7 | 1 | ||||||||||||||||||
| 3 | F Passaro | 6 | 3 | 6 | Alt | T Skatov | 5 | 62 | |||||||||||||||||||
| 5 | M Cecchinato | 6 | 6 | 5 | M Cecchinato | 7 | 77 | ||||||||||||||||||||
| LL |  D Michalski | 1 | 2 | 5 | M Cecchinato | 6 | 77 | ||||||||||||||||||||
| Alt |  M Zekić | 4 | 4 | G Mager | 1 | 62 | |||||||||||||||||||||
| G Mager | 6 | 6 | 5 | M Cecchinato | 77 | 6 | |||||||||||||||||||||
| Q | J Barranco Cosano | 4 | 2 | 2 | C Taberner | 62 | 4 | ||||||||||||||||||||
| N Milojević | 6 | 6 | N Milojević | 0 | 78 | 65 | |||||||||||||||||||||
| C-M Stebe | 4 | 4 | 2 | C Taberner | 6 | 66 | 77 | ||||||||||||||||||||
| 2 | C Taberner | 6 | 6 | ||||||||||||||||||||||||
Marin Čilić was the defending champion and successfully defended his title, defeating Tommy Haas in the final, 6–3, 6–4.
Fabio Fognini was the defending champion, but lost in the semifinals to Roberto Bautista Agut.
Bautista Agut went on to win the title, defeating Lukáš Rosol in the final, 6–3, 4–6, 6–2.
Marcel Granollers was the defending champion, but lost in the quarterfinals to Dominic Thiem.
David Goffin won the title, defeating Thiem in the final, 4–6, 6–1, 6–3.
Rafael Nadal was the defending champion, but lost in the semifinals to Fabio Fognini.
David Ferrer was the three-time defending champion, but he chose to compete in Acapulco instead.
Rafael Nadal won the title, defeating Juan Mónaco in the final, 6–4, 6–1.
Rafael Nadal was the defending champion, but lost to Dominic Thiem in the semifinals.
Dominic Thiem was the defending champion and successfully defended his title, defeating Alexander Zverev in the final, 6–4, 3–6, 6–0.
Andrey Kuznetsov was the defending champion but chose not to defend his title.
Pablo Cuevas was the two-time defending champion and successfully defended his title, defeating Albert Ramos Viñolas in the final, 6–7(3–7), 6–4, 6–4.
Constant Lestienne was the defending champion but retired in the first round against Simone Bolelli.
Marco Cecchinato was the defending champion but lost in the semifinals to Federico Delbonis.
Alexandr Dolgopolov was the defending champion, but withdrew before the tournament began.
Dominic Thiem was the defending champion, but lost in the quarterfinals to Fernando Verdasco.
Rogério Dutra Silva was the defending champion but lost in the quarterfinals to Carlos Gómez-Herrera.
Lucas Pouille was the defending champion, but lost in the second round to John Millman.
Andrey Rublev was the defending champion, but lost in the quarterfinals to Robin Haase. This was Rublev's first tournament back on tour after missing three months due to a stress fracture in his back.
Marco Cecchinato was the defending champion, but withdrew due to illness.
Andrea Collarini was the defending champion but lost in the first round to Marco Cecchinato.
Marcos Giron was the defending champion but chose not to defend his title.
Alexander Zverev was the defending champion from when the event was held in 2019, but chose not to defend his title.