| Doubles | |
|---|---|
| 2022 Mercer Tennis Classic | |
| Champions |  Anna Rogers Christina Rosca |
| Runners-up | Madison Brengle Maria Mateas |
| Final score | 6–4, 6–4 |
Quinn Gleason and Catherine Harrison were the defending champions [1] but chose not to participate.
Anna Rogers and Christina Rosca won the title, defeating Madison Brengle and Maria Mateas in the final, 6–4, 6–4.
Anna Rogers / Christina Rosca (champions)
Alexandra Osborne / Adriana Reami (semifinals) Madison Brengle / Maria Mateas (final)
Thaísa Grana Pedretti / 
Nadia Podoroska (quarterfinals, withdrew)| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | A Rogers C Rosca | 6 | 6 | ||||||||||||||||||||||||
| V Osuigwe W Osuigwe | 2 | 2 | 1 | A Rogers C Rosca | 77 | 6 | |||||||||||||||||||||
 R Bhatia  D Evtimova | 6 | 6 | R Bhatia D Evtimova | 63 | 4 | ||||||||||||||||||||||
| WC | M Courville  T Ristić | 2 | 3 | 1 | A Rogers C Rosca | 6 | 6 | ||||||||||||||||||||
| 4 | TG Pedretti N Podoroska | 6 | 6 | C Ansari  A Arseneault | 3 | 3 | |||||||||||||||||||||
| S Mohamad R Newborn | 2 | 2 | 4 | TG Pedretti N Podoroska | |||||||||||||||||||||||
| C Ansari A Arseneault | 6 | 6 | C Ansari A Arseneault | w/o | |||||||||||||||||||||||
 L Dekmeijere  F Norin | 1 | 1 | 1 | A Rogers C Rosca | 6 | 6 | |||||||||||||||||||||
E Danailova  L Petruželová | 77 | 6 | 3 | M Brengle M Mateas | 4 | 4 | |||||||||||||||||||||
B Fernandez  O Lincer | 64 | 1 | E Danailova L Petruželová | 0 | 0 | ||||||||||||||||||||||
| A Urhobo M Yamakita | 1 | 1 | 3 | M Brengle M Mateas | 6 | 6 | |||||||||||||||||||||
| 3 | M Brengle M Mateas | 6 | 6 | 3 | M Brengle M Mateas | 6 | 6 | ||||||||||||||||||||
| WC | M Aubuchon M Lewis | 6 | 4 | [10] | 2 | A Osborne A Reami | 2 | 3 | |||||||||||||||||||
| WC |  C Ciaccia  ES Schlagenhauf | 3 | 6 | [3] | WC | M Aubuchon M Lewis | 4 | 5 | |||||||||||||||||||
| S Ewing A Smith | 77 | 4 | [7] | 2 | A Osborne A Reami | 6 | 7 | ||||||||||||||||||||
| 2 | A Osborne A Reami | 63 | 6 | [10] | |||||||||||||||||||||||
Melanie Oudin was the defending champion, but chose to compete at the 2013 Tevlin Women's Challenger instead.
Shelby Rogers was the defending champion, but decided not to participate.
Shelby Rogers was the defending champion, having won the event in 2013, but chose not to participate.
Garbiñe Muguruza was the defending champion heading into the tournament but chose to compete at the Sydney tennis event instead of Hobart. In the final, it was unseeded Brit Heather Watson who defeated the American qualifier in Madison Brengle, 6–3, 6–4 to record her second WTA title.
Anna Schmiedlová was the defending champion, but chose not to participate.
Samantha Stosur was the defending champion, but chose not to participate.
Madison Brengle was the defending champion, but she chose to compete in Wuhan instead.
Petra Kvitová was the defending champion, but lost in the first round to Peng Shuai.
Agnieszka Radwańska was the defending champion, but lost in the third round to Daria Kasatkina.
Anna Karolína Schmiedlová was the defending champion, but chose to compete in Poitiers instead.
Bianca Andreescu was the defending champion, but chose not to participate this year.
Viktorija Golubic was the defending champion but chose not to participate.
Madison Keys was the defending champion but lost in the second round to Ons Jabeur.
Shelby Rogers was the defending champion, but chose not to participate.
Veronika Kudermetova and Anastasia Pavlyuchenkova defeated reigning champion Giuliana Olmos and partner Gabriela Dabrowski in the final, 1–6, 6–4, [10–7] to win the women's doubles tennis title at the 2022 Italian Open.
Hailey Baptiste and Whitney Osuigwe were the defending champions but chose not to participate.
Kylie Collins and Robin Montgomery were the defending champions but Montgomery chose not to participate.
Hayley Carter and Luisa Stefani were the defending champions but chose not to participate.
Shelby Rogers was the defending champion but chose not to participate.
The 2022 Mercer Tennis Classic is a professional tennis tournament played on outdoor hard courts. It is the tenth edition of the tournament which is part of the 2022 ITF Women's World Tennis Tour. It takes place in Macon, Georgia, United States between 17 and 23 October 2022.