| Singles | |
|---|---|
| 2022 Tallahassee Tennis Challenger | |
| Champion |  Wu Tung-lin |
| Runner-up |  Michael Mmoh |
| Score | 6–3, 6–4 |
Jenson Brooksby was the defending champion [1] but chose not to defend his title.
Wu Tung-lin won the title after defeating Michael Mmoh 6–3, 6–4 in the final.
Tomás Martín Etcheverry (second round) Steve Johnson (first round)
Daniel Elahi Galán (semifinals)
Emilio Gómez (second round)
Tomás Barrios Vera (second round) J. J. Wolf (quarterfinals) Mitchell Krueger (second round, retired) Tennys Sandgren (first round)| Semifinals | Final | ||||||||||||
| Michael Mmoh | 3 | 7 | 6 | ||||||||||
| 3 | Daniel Elahi Galán | 6 | 5 | 4 | |||||||||
| Michael Mmoh | 3 | 4 | |||||||||||
| Wu Tung-lin | 6 | 6 | |||||||||||
| Wu Tung-lin | 6 | 79 | |||||||||||
 Zhang Zhizhen | 4 | 67 | |||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | TM Etcheverry | 6 | 6 | ||||||||||||||||||||||||
| J Jung | 3 | 2 | 1 | TM Etcheverry | 6 | 3 | 3 | ||||||||||||||||||||
| M Mmoh | 6 | 6 | M Mmoh | 4 | 6 | 6 | |||||||||||||||||||||
 S Nagal | 3 | 0 | M Mmoh | 6 | 77 | ||||||||||||||||||||||
| Q | Christian Langmo | 2 | 61 | WC | A Kovacevic | 2 | 64 | ||||||||||||||||||||
| WC | A Kovacevic | 6 | 77 | WC | A Kovacevic | 77 | 6 | ||||||||||||||||||||
| R Ramanathan | 1 | 3 | 5 | T Barrios Vera | 64 | 4 | |||||||||||||||||||||
| 5 | T Barrios Vera | 6 | 6 | M Mmoh | 3 | 7 | 6 | ||||||||||||||||||||
| 3 | DE Galán | 6 | 6 | 3 | DE Galán | 6 | 5 | 4 | |||||||||||||||||||
| A Collarini | 4 | 3 | 3 | DE Galán | 6 | 77 | |||||||||||||||||||||
| WC | A Rybakov | 63 | 3 |  J Kubler | 1 | 65 | |||||||||||||||||||||
| J Kubler | 77 | 6 | 3 | DE Galán | 6 | 6 | |||||||||||||||||||||
| Q |  G Brouwer | 1 | 6 | 61 |  Yo Watanuki | 3 | 4 | ||||||||||||||||||||
| Yo Watanuki | 6 | 1 | 77 | Yo Watanuki | 77 | 6 | |||||||||||||||||||||
| G Lama | 7 | 63 | 78 | G Lama | 62 | 0 | |||||||||||||||||||||
| 8 | T Sandgren | 5 | 77 | 66 | |||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 7 | M Krueger | 7 | 6 | ||||||||||||||||||||||||
| N Moreno de Alboran | 5 | 4 | 7 | M Krueger | 4 | 0r | |||||||||||||||||||||
| C Harrison | 6 | 6 | C Harrison | 6 | 0 | ||||||||||||||||||||||
| P Gunneswaran | 3 | 3 | C Harrison | 0 | 4 | ||||||||||||||||||||||
| T-l Wu | 6 | 6 | T-l Wu | 6 | 6 | ||||||||||||||||||||||
| WC |  Antoine Cornut Chauvinc | 3 | 2 | T-l Wu | 6 | 61 | 6 | ||||||||||||||||||||
| Q |  M Torpegaard | 6 | 5 | 4 | 4 | E Gómez | 0 | 77 | 1 | ||||||||||||||||||
| 4 | E Gómez | 3 | 7 | 6 | T-l Wu | 6 | 79 | ||||||||||||||||||||
| 6 | J. J. Wolf | 77 | 5 | 6 | Zh Zhang | 4 | 67 | ||||||||||||||||||||
| Q |  D Dutra da Silva | 65 | 7 | 2 | 6 | J. J. Wolf | 77 | 6 | |||||||||||||||||||
 A Ritschard | 6 | 6 | A Ritschard | 65 | 3 | ||||||||||||||||||||||
| Q |  J Mridha | 2 | 4 | 6 | J. J. Wolf | 3 | 6 | 62 | |||||||||||||||||||
 E Donskoy | 6 | 6 | Zh Zhang | 6 | 3 | 77 | |||||||||||||||||||||
| Q | A Fils | 0 | 4 | E Donskoy | 61 | 5 | |||||||||||||||||||||
| Zh Zhang | 2 | 6 | 7 | Zh Zhang | 77 | 7 | |||||||||||||||||||||
| 2 | S Johnson | 6 | 3 | 5 | |||||||||||||||||||||||
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