| Singles | |
|---|---|
| 2023 Open Città della Disfida | |
| Champion |  Shintaro Mochizuki |
| Runner-up |  Santiago Rodríguez Taverna |
| Score | 6–1, 6–4 |
Nuno Borges was the defending champion [1] but chose not to defend his title.
Shintaro Mochizuki won the title after defeating Santiago Rodríguez Taverna 6–1, 6–4 in the final.
Alexander Shevchenko (first round)
Filip Misolic (first round)
Franco Agamenone (semifinals)
Benoît Paire (first round) Francesco Maestrelli (first round) Laurent Lokoli (quarterfinals)
Zdeněk Kolář (second round) Flavio Cobolli (first round)| Semifinals | Final | ||||||||||||
| Shintaro Mochizuki | 6 | 5 | 6 | ||||||||||
| 3 | Franco Agamenone | 4 | 7 | 2 | |||||||||
| Shintaro Mochizuki | 6 | 6 | |||||||||||
| Santiago Rodríguez Taverna | 1 | 4 | |||||||||||
| Santiago Rodríguez Taverna | 6 | 6 | |||||||||||
 Nicholas David Ionel | 4 | 4 | |||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | A Shevchenko | 3 | 7 | 4 | |||||||||||||||||||||||
| JB Torres | 6 | 5 | 6 | JB Torres | 2 | 5 | |||||||||||||||||||||
| WC | F Arnaboldi | 2 | 3 | S Mochizuki | 6 | 7 | |||||||||||||||||||||
| S Mochizuki | 6 | 6 | S Mochizuki | 6 | 6 | ||||||||||||||||||||||
 Z Piros | 3 | 6 | 6 | Z Piros | 4 | 1 | |||||||||||||||||||||
| Q | Edoardo Lavagno | 6 | 1 | 3 | Z Piros | 3 | 6 | 6 | |||||||||||||||||||
| Q | J Ocleppo | 63 | 6 | 2 | 7 | Z Kolář | 6 | 3 | 2 | ||||||||||||||||||
| 7 | Z Kolář | 77 | 2 | 6 | S Mochizuki | 6 | 5 | 6 | |||||||||||||||||||
| 3 | F Agamenone | 6 | 6 | 3 | F Agamenone | 4 | 7 | 2 | |||||||||||||||||||
| Alt |  J McCabe | 0 | 1 | 3 | F Agamenone | 3 | |||||||||||||||||||||
 M Zekić | 6 | 1 | 67 | M Gigante | 2r | ||||||||||||||||||||||
| M Gigante | 3 | 6 | 79 | 3 | F Agamenone | 7 | 6 | ||||||||||||||||||||
| T Droguet | 77 | 77 | 6 | L Lokoli | 5 | 2 | |||||||||||||||||||||
| Q | S Napolitano | 64 | 62 | T Droguet | 6 | 5 | 4 | ||||||||||||||||||||
| WC | G Mager | 64 | 3 | 6 | L Lokoli | 4 | 7 | 6 | |||||||||||||||||||
| 6 | L Lokoli | 77 | 6 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 5 | F Maestrelli | 3 | 0 | ||||||||||||||||||||||||
| A Pellegrino | 6 | 6 | A Pellegrino | 6 | 6 | ||||||||||||||||||||||
| Q | S Travaglia | 712 | 6 | Q | S Travaglia | 2 | 2 | ||||||||||||||||||||
 N Serdarušić | 610 | 3 | A Pellegrino | 3 | 5 | ||||||||||||||||||||||
| D Sweeny | 1 | 64 | S Rodríguez Taverna | 6 | 7 | ||||||||||||||||||||||
| Q | J Berrettini | 6 | 77 | Q | J Berrettini | 2 | 2 | ||||||||||||||||||||
| S Rodríguez Taverna | 6 | 4 | 6 | S Rodríguez Taverna | 6 | 6 | |||||||||||||||||||||
| 4 | B Paire | 2 | 6 | 4 | S Rodríguez Taverna | 6 | 6 | ||||||||||||||||||||
| 8/WC | F Cobolli | 4 | 61 | ND Ionel | 4 | 4 | |||||||||||||||||||||
| LL | S Caruso | 6 | 77 | LL | S Caruso | 2 | 4 | ||||||||||||||||||||
 S Diez | 77 | 6 | S Diez | 6 | 6 | ||||||||||||||||||||||
| FC Jianu | 65 | 1 | S Diez | 1 | 2 | ||||||||||||||||||||||
| Q | Gabriele Piraino | 4 | 6 | 3 | ND Ionel | 6 | 6 | ||||||||||||||||||||
| ND Ionel | 6 | 4 | 6 | ND Ionel | 6 | 6 | |||||||||||||||||||||
| M Navone | 7 | 7 | M Navone | 1 | 4 | ||||||||||||||||||||||
| 2 | F Misolic | 5 | 5 | ||||||||||||||||||||||||
This was the second of four editions of the tournament in the 2021 ATP Challenger Tour calendar.
Gerard Granollers and Fabrício Neis were the defending champions but chose not to defend their title.
Carlos Taberner was the defending champion but was not eligible to compete in the tournament due to his ATP ranking.
Pedro Sousa was the defending champion but chose not to defend his title.
Nuno Borges was the defending champion but chose not to defend his title.
Geoffrey Blancaneaux was the defending champion but chose not to defend his title.
Pavel Kotov was the defending champion but chose not to defend his title.
Gastão Elias was the defending champion and successfully defended his title, defeating Nino Serdarušić 6–3, 6–4 in the final.
Jesper de Jong and Tim van Rijthoven were the defending champions but chose not to defend their title.
Giulio Zeppieri was the defending champion but lost in the first round to Matteo Arnaldi.
Nuno Borges and Francisco Cabral defeated Máximo González and André Göransson in the final, 6–2, 6–3 to win the doubles tennis title at the 2022 Estoril Open. Borges and Cabral had entered the tournament through a wildcard.
Pablo Cuevas was the defending champion but chose not to defend his title.
Benjamin Bonzi was the defending champion but chose not to defend his title.
Alex Molčan was the defending champion but chose not to defend his title.
Thiago Monteiro was the defending champion but chose not to defend his title.
Brandon Nakashima was the defending champion but chose not to defend his title.
Holger Rune was the defending champion but chose not to defend his title.
Tseng Chun-hsin was the defending champion but chose not to defend his title.
Nuno Borges and Francisco Cabral were the defending champions but lost in the final to Julian Cash and Henry Patten.
Fernando Verdasco was the defending champion but chose not to defend his title.