| Singles | |
|---|---|
| 2023 Open Villa de Madrid | |
| Champion |  Olga Danilović |
| Runner-up |  Sara Sorribes Tormo |
| Score | 6–2, 6–3 |
Aliona Bolsova was the defending champion [1] but chose not to participate.
Olga Danilović won the title, defeating Sara Sorribes Tormo in the final, 6–2, 6–3. [2]
Leylah Fernandez (semifinals)
Emma Navarro (first round)
Dalma Gálfi (second round, retired)
Nadia Podoroska (first round)
Arantxa Rus (quarterfinals, withdrew)
Kimberly Birrell (first round)
Simona Waltert (second round) Marina Bassols Ribera (first round)| Semifinals | Final | ||||||||||||
| 1/WC | Leylah Fernandez | 2 | 5 | ||||||||||
| Sara Sorribes Tormo | 6 | 7 | |||||||||||
| Sara Sorribes Tormo | 2 | 3 | |||||||||||
| Olga Danilović | 6 | 6 | |||||||||||
| Q | Suzan Lamens | 4 | 1 | ||||||||||
| Olga Danilović | 6 | 6 | |||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1/WC | L Fernandez | 6 | 6 | ||||||||||||||||||||||||
| Q | C Perrin | 0 | 2 | 1/WC | L Fernandez | 4 | 6 | 77 | |||||||||||||||||||
 E Arango | 6 | 6 | E Arango | 6 | 2 | 65 | |||||||||||||||||||||
| J Fourlis | 2 | 2 | 1/WC | L Fernandez | w/o | ||||||||||||||||||||||
| L Romero Gormaz | 4 | 2 | 5 | A Rus | |||||||||||||||||||||||
| Q | L Cortez Llorca | 6 | 6 | Q | L Cortez Llorca | 1 | 3 | ||||||||||||||||||||
| J Bouzas Maneiro | 2 | 2 | 5 | A Rus | 6 | 6 | |||||||||||||||||||||
| 5 | A Rus | 6 | 6 | 1/WC | L Fernandez | 2 | 5 | ||||||||||||||||||||
| 4 | N Podoroska | 1 | 4 | S Sorribes Tormo | 6 | 7 | |||||||||||||||||||||
 J Cristian | 6 | 6 | J Cristian | 6 | 6 | ||||||||||||||||||||||
 M Hontama | 6 | 6 | M Hontama | 1 | 0 | ||||||||||||||||||||||
 D Papamichail | 4 | 1 | J Cristian | 3 | 77 | 2 | |||||||||||||||||||||
| WC | Á Fita Boluda | 2 | 1 | S Sorribes Tormo | 6 | 63 | 6 | ||||||||||||||||||||
| S Sorribes Tormo | 6 | 6 | S Sorribes Tormo | 6 | 6 | ||||||||||||||||||||||
| M Uchijima | 6 | 6 | M Uchijima | 4 | 1 | ||||||||||||||||||||||
| 6 | K Birrell | 2 | 1 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 7 | S Waltert | 6 | 6 | ||||||||||||||||||||||||
| P Ormaechea | 0 | 2 | 7 | S Waltert | 0 | 7 | 3 | ||||||||||||||||||||
| Q |  T Prozorova | 1 | 2 | Q | A Lázaro García | 6 | 5 | 6 | |||||||||||||||||||
| Q | A Lázaro García | 6 | 6 | Q | A Lázaro García | 6 | 3 | 3 | |||||||||||||||||||
| Q |  M Tona | 0 | 0 | Q | S Lamens | 4 | 6 | 6 | |||||||||||||||||||
| Q | S Lamens | 6 | 6 | Q | S Lamens | 5 | |||||||||||||||||||||
| Ar Rodionova | 1 | 6 | 2 | 3 | D Gálfi | 1r | |||||||||||||||||||||
| 3 | D Gálfi | 6 | 1 | 6 | Q | S Lamens | 4 | 1 | |||||||||||||||||||
| 8 | M Bassols Ribera | 2 | 0 | O Danilović | 6 | 6 | |||||||||||||||||||||
| O Danilović | 6 | 6 | O Danilović | 6 | 6 | ||||||||||||||||||||||
| Q | L Moreno Arias | 2 | 0 | WC | I Burillo Escorihuela | 0 | 0 | ||||||||||||||||||||
| WC | I Burillo Escorihuela | 6 | 6 | O Danilović | 6 | 6 | |||||||||||||||||||||
| Q |  K Zavatska | 3 | 6 | 6 | Q | K Zavatska | 2 | 4 | |||||||||||||||||||
| WC | M Soriano Santiago | 6 | 2 | 2 | Q | K Zavatska | 0 | 710 | 6 | ||||||||||||||||||
 C Tauson | 6 | 6 | C Tauson | 6 | 68 | 1 | |||||||||||||||||||||
| 2 | E Navarro | 2 | 4 | ||||||||||||||||||||||||
Vera Lapko won the title, defeating defending champion Tereza Mihalíková in the final, 6–3, 6–4.
Anastasia Potapova was the defending champion, but chose to compete in the Ladies' Singles main draw as a qualifier, where she retired in the first round against Tatjana Maria.
Amanda Anisimova won the title, defeating Coco Gauff in the final, 6–0, 6–2.
Jada Hart and Ena Shibahara were the defending champions, but both players were ineligible to participate.
This was the first edition of the tournament.
Olga Danilović and Marta Kostyuk were the defending champions, but both players chose not to participate.
Barbora Strýcová was the defending champion, but lost in the quarterfinals to Alison Van Uytvanck.
Carina Witthöft was the defending champion, but lost in the first round to Vera Lapko.
Elise Mertens was the defending champion, but lost in the quarterfinals to Maria Sakkari.
Kathinka von Deichmann was the defending champion, but lost in the first round to Maryna Zanevska.
Iga Świątek was the defending champion, but chose not to participate.
Petra Martić was the defending champion, but she chose not to participate as she was still competing at the 2020 US Open.
Ana Konjuh was the defending champion but chose to compete in Madrid instead.
Simona Halep was the defending champion, having won the previous edition in 2013, but chose not to participate.
Petra Martić defeated Olga Danilović in the final, 6–4, 6–2 to win the singles tennis title at the 2022 Ladies Open Lausanne. It was Martić's first WTA title since Istanbul in 2019.
This was the first edition of the tournament.
This was the first edition of the tournament.
This is the first edition of the event as a WTA 125 tournament. It was part of the ITF Women's Circuit from 2016 to 2018. Viktória Kužmová was the champion when the event was last held in 2018, but lost in the first round of qualifying to Amarissa Kiara Tóth.
This was the first edition of the tournament.
Olga Danilović was the defending champion, but lost in the second round to Leyre Romero Gormaz.