| Singles | |
|---|---|
| 2024 Challenger Ciudad de Guayaquil | |
| Champion |  Federico Agustín Gómez |
| Runner-up |  Tomás Barrios Vera |
| Score | 6–1, 6–4 |
Alejandro Tabilo was the defending champion [1] but chose not to defend his title.
Federico Agustín Gómez won the title after defeating Tomás Barrios Vera 6–1, 6–4 in the final.
Francisco Comesaña (second round) Federico Coria (semifinals)
Daniel Elahi Galán (first round) Román Andrés Burruchaga (semifinals) Marco Trungelliti (first round) Juan Manuel Cerúndolo (second round, retired)
Vít Kopřiva (second round) Federico Agustín Gómez (champion)| Semifinals | Final | ||||||||||||
| 8 | Federico Agustín Gómez | 6 | 6 | ||||||||||
| 4 | Román Andrés Burruchaga | 3 | 0 | ||||||||||
| 8 | Federico Agustín Gómez | 6 | 6 | ||||||||||
| Tomás Barrios Vera | 1 | 4 | |||||||||||
| Tomás Barrios Vera | 4 | 7 | 6 | ||||||||||
| 2 | Federico Coria | 6 | 5 | 1 | |||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | F Comesaña | 6 | 6 | ||||||||||||||||||||||||
| WC |  Francisco Castro | 1 | 0 | 1 | F Comesaña | 3 | 4 | ||||||||||||||||||||
 V Gaubas | 4 | 6 | 3 | Q | A Barrena | 6 | 6 | ||||||||||||||||||||
| Q | Alex Barrena | 6 | 3 | 6 | Q | A Barrena | 3 | 2 | |||||||||||||||||||
| WC | Ángel Véliz | 0 | 1 | 8 | FA Gómez | 6 | 6 | ||||||||||||||||||||
| Q |  Ryan Nijboer | 6 | 6 | Q | R Nijboer | 6 | 3 | 0 | |||||||||||||||||||
| Q |  Mathys Erhard | 4 | 6 | 4 | 8 | FA Gómez | 3 | 6 | 6 | ||||||||||||||||||
| 8 | FA Gómez | 6 | 4 | 6 | 8 | FA Gómez | 6 | 6 | |||||||||||||||||||
| 4 | RA Burruchaga | 77 | 0 | 4 | RA Burruchaga | 3 | 0 | ||||||||||||||||||||
 P Sakamoto | 61 | 0r | 4 | RA Burruchaga | 1 | 6 | 7 | ||||||||||||||||||||
 M Dellien | 6 | 6 | M Dellien | 6 | 4 | 5 | |||||||||||||||||||||
| WC | Marcos Lee Chan Baratau | 1 | 0 | 4 | RA Burruchaga | 4 | 6 | 6 | |||||||||||||||||||
| Alt |  G Elias | 1 | 1 |  O Roca Batalla | 6 | 2 | 4 | ||||||||||||||||||||
| O Roca Batalla | 6 | 6 | O Roca Batalla | 6 | 6 | ||||||||||||||||||||||
| Q |  Garrett Johns | 3 | 1 | 7 | V Kopřiva | 3 | 4 | ||||||||||||||||||||
| 7 | V Kopřiva | 6 | 6 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 6 | JM Cerúndolo | 6 | 6 | ||||||||||||||||||||||||
| Alt | R Olivo | 2 | 3 | 6 | JM Cerúndolo | 5 | 77 | 3r | |||||||||||||||||||
| H Rocha | 4 | 6 | 6 | H Rocha | 7 | 65 | 3 | ||||||||||||||||||||
| Q |  Gerard Campana Lee | 6 | 2 | 2 | H Rocha | 1 | 2 | ||||||||||||||||||||
 E Møller | 6 | 5 | 4 | T Barrios Vera | 6 | 6 | |||||||||||||||||||||
 G Bueno | 4 | 7 | 6 | G Bueno | 64 | 2 | |||||||||||||||||||||
| T Barrios Vera | 6 | 7 | T Barrios Vera | 77 | 6 | ||||||||||||||||||||||
| 3 | DE Galán | 4 | 5 | T Barrios Vera | 4 | 7 | 6 | ||||||||||||||||||||
| 5 | M Trungelliti | 7 | 3 | 63 | 2 | F Coria | 6 | 5 | 1 | ||||||||||||||||||
| A Andrade | 5 | 6 | 77 | A Andrade | 77 | 6 | |||||||||||||||||||||
| JP Varillas | 5 | 6 | 6 | JP Varillas | 63 | 2 | |||||||||||||||||||||
| I Buse | 7 | 4 | 1 | A Andrade | 2 | 0r | |||||||||||||||||||||
| Alt |  F Roncadelli | 0 | 2 | 2 | F Coria | 6 | 1 | ||||||||||||||||||||
| Q | Mariano Kestelboim | 6 | 6 | Q | M Kestelboim | 5 | 2 | ||||||||||||||||||||
| PR | N Kicker | 65 | 4 | 2 | F Coria | 7 | 6 | ||||||||||||||||||||
| 2 | F Coria | 77 | 6 | ||||||||||||||||||||||||
Víctor Estrella Burgos was the two-time defending champion and successfully defended his title, defeating Paolo Lorenzi in the final, 6–7(2–7), 7–5, 7–6(8–6).
Roberto Carballés Baena was the defending champion but chose not to defend his title.
Thiago Seyboth Wild was the defending champion but chose not to defend his title.
Cristian Garín defeated Facundo Bagnis in the final, 6–4, 6–7(3–7), 7–5 to capture the men's singles tennis title at the 2021 Chile Open.
Jannik Sinner was the defending champion but chose not to defend his title.
Julian Lenz and Gerald Melzer were the defending champions but chose not to defend their title.
Albert Ramos Viñolas defeated Alejandro Tabilo in the final, 4–6, 6–3, 6–4 to win the singles title at the 2022 Córdoba Open.
Pedro Martínez defeated Sebastián Báez in the final, 4–6, 6–4, 6–4 to win the singles title at the 2022 Chile Open. It was his first ATP Tour title.
Alejandro Tabilo was the defending champion but chose not to defend his title.
Matteo Arnaldi was the defending champion but chose not to defend his title.
Pedro Cachin was the defending champion but chose not to defend his title.
Genaro Alberto Olivieri was the defending champion but chose not to defend his title.
Luciano Darderi defeated Facundo Bagnis in the final, 6–1, 6–4 to win the singles tennis title at the 2024 Córdoba Open. It was his first ATP Tour title. This was only the third final in ATP history to be contested between two qualifiers, following the 2015 Sydney International and the 2018 Austrian Open.
Federico Agustín Gómez and Nicolás Kicker were the defending champions but only Gómez chose to defend his title, partnering Scott Duncan. He lost in the quarterfinals to Alexander Ritschard and Benjamin Sigouin.
William Blumberg and Luis David Martínez were the defending champions but only Martínez chose to defend his title, partnering Federico Agustín Gómez. He lost in the semifinals to Christian Harrison and Marcus Willis.
Hugo Gaston was the defending champion but chose not to defend his title.
Mariano Navone was the defending champion but chose not to defend his title.
Nicolás Kicker was the defending champion but lost in the first round to Gustavo Heide.
Thiago Monteiro was the defending champion but chose not to defend his title.
Arklon and Conner Huertas del Pino were the defending champions but lost in the quarterfinals to Karol Drzewiecki and Piotr Matuszewski.