| Singles | |
|---|---|
| 2024 Challenger de Santiago | |
| Champion |  Juan Pablo Varillas |
| Runner-up |  Facundo Bagnis |
| Score | 6–3, 6–2 |
Hugo Dellien was the defending champion [1] but lost in the quarterfinals to Facundo Bagnis.
Juan Pablo Varillas won the title after defeating Bagnis 6–3, 6–2 in the final.
Tomás Barrios Vera (first round) Juan Pablo Varillas (champion) Camilo Ugo Carabelli (quarterfinals) Facundo Bagnis (final) Román Andrés Burruchaga (first round) Juan Manuel Cerúndolo (second round)
Hugo Dellien (quarterfinals) Genaro Alberto Olivieri (second round)| Semifinals | Final | ||||||||||||
 Gustavo Heide | 4 | 61 | |||||||||||
| 4 | Facundo Bagnis | 6 | 77 | ||||||||||
| 4 | Facundo Bagnis | 3 | 2 | ||||||||||
| 2 | Juan Pablo Varillas | 6 | 6 | ||||||||||
 Liam Draxl | 3 | 2 | |||||||||||
| 2 | Juan Pablo Varillas | 6 | 6 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | T Barrios Vera | 3 | 4 | ||||||||||||||||||||||||
| G Heide | 6 | 6 | G Heide | 7 | 6 | ||||||||||||||||||||||
 Edoardo Lavagno | 3 | 1 | A Collarini | 5 | 1 | ||||||||||||||||||||||
| A Collarini | 6 | 6 | G Heide | 6 | 77 | ||||||||||||||||||||||
| Q | V Aboian | 6 | 6 | G Mager | 2 | 65 | |||||||||||||||||||||
| Alt | M Pucinelli de Almeida | 4 | 4 | Q | V Aboian | 7 | 1 | 2 | |||||||||||||||||||
| G Mager | 3 | 6 | 6 | G Mager | 5 | 6 | 6 | ||||||||||||||||||||
| 5 | RA Burruchaga | 6 | 3 | 3 | G Heide | 4 | 61 | ||||||||||||||||||||
| 4 | F Bagnis | 6 | 7 | 4 | F Bagnis | 6 | 77 | ||||||||||||||||||||
| Q |  Gerard Campana Lee | 1 | 5 | 4 | F Bagnis | 6 | 6 | ||||||||||||||||||||
| Q |  GA Boitan | 6 | 6 | Q | GA Boitan | 4 | 2 | ||||||||||||||||||||
| Q | Mariano Kestelboim | 4 | 4 | 4 | F Bagnis | 6 | 710 | ||||||||||||||||||||
| WC | J Fonseca | 62 | 6 | 4 | 7 | H Dellien | 3 | 68 | |||||||||||||||||||
| Q | FA Gómez | 77 | 2 | 6 | Q | FA Gómez | 6 | 1 | 0 | ||||||||||||||||||
| G Bueno | 4 | 64 | 7 | H Dellien | 3 | 6 | 6 | ||||||||||||||||||||
| 7 | H Dellien | 6 | 77 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 8 | GA Olivieri | 2 | 7 | 6 | |||||||||||||||||||||||
 G Oliveira | 6 | 5 | 2 | 8 | GA Olivieri | 1 | 6 | 1 | |||||||||||||||||||
| L Draxl | 67 | 6 | 77 | L Draxl | 6 | 4 | 6 | ||||||||||||||||||||
 P Sekulic | 79 | 4 | 62 | L Draxl | 6 | 5 | 7 | ||||||||||||||||||||
| Alexander Weis | 6 | 4 | 2 | 3 | C Ugo Carabelli | 4 | 7 | 5 | |||||||||||||||||||
| WC | I Buse | 4 | 6 | 6 | WC | I Buse | 69 | 4 | |||||||||||||||||||
| WC | M Soto | 6 | 4 | 3 | 3 | C Ugo Carabelli | 711 | 6 | |||||||||||||||||||
| 3 | C Ugo Carabelli | 4 | 6 | 6 | L Draxl | 3 | 2 | ||||||||||||||||||||
| 6 | JM Cerúndolo | 6 | 6 | 2 | JP Varillas | 6 | 6 | ||||||||||||||||||||
| JL Reis da Silva | 1 | 0 | 6 | JM Cerúndolo | 1 | 5 | |||||||||||||||||||||
| F Passaro | 6 | 6 | F Passaro | 6 | 7 | ||||||||||||||||||||||
| M Dellien | 0 | 4 | F Passaro | 5 | 6 | 66 | |||||||||||||||||||||
| Q | O Luz | 6 | 2 | 2 | JP Varillas | 7 | 4 | 78 | |||||||||||||||||||
| R Olivo | 3 | 1d | Q | O Luz | 3 | 6 | 63 | ||||||||||||||||||||
| PR |  P Jubb | 6 | 3 | 66 | 2 | JP Varillas | 6 | 2 | 77 | ||||||||||||||||||
| 2 | JP Varillas | 3 | 6 | 78 | |||||||||||||||||||||||
Gastão Elias was the defending champion but lost in the first round to Camilo Ugo Carabelli.
Víctor Estrella Burgos was the defending champion but lost in the first round to Federico Delbonis.
This was the first edition of the tournament.
Pablo Andújar was the defending champion but chose not to defend his title.
Cristian Garín was the defending champion but chose not to defend his title.
Cristian Garín was the defending champion but chose not to defend his title.
Guido Andreozzi was the defending champion but chose not to defend his title.
Guido Pella was the defending champion but chose not to defend his title.
Juan Ignacio Londero was the defending champion, but lost to Laslo Đere in the quarterfinals.
Cristian Garín was the defending champion, but chose not to defend his title.
Cristian Garín defeated Facundo Bagnis in the final, 6–4, 6–7(3–7), 7–5 to capture the men's singles tennis title at the 2021 Chile Open.
Oscar Otte was the defending champion but retired in the quarterfinals to Elias Ymer.
Daniel Elahi Galán was the defending champion but chose not to defend his title.
Jaume Munar was the defending champion but lost in the semifinals to Juan Ignacio Londero.
This was the first edition of the tournament.
Francisco Cerúndolo was the defending champion but chose not to defend his title.
Defending champion Casper Ruud defeated Matteo Berrettini in the final, 4–6, 7–6(7–4), 6–2 to win the singles tennis title at the 2022 Swiss Open Gstaad.
Sebastián Báez was the defending champion but chose not to defend his title.
Thiago Agustín Tirante was the defending champion but lost in the semifinals to Facundo Bagnis.
Álvaro Guillén Meza was the defending champion but lost in the second round to Mariano Navone.