| Singles | |
|---|---|
| 2024 Santa Cruz Challenger | |
| Champion |  Camilo Ugo Carabelli |
| Runner-up |  Murkel Dellien |
| Score | 6–4, 6–2 |
Mariano Navone was the defending champion [1] but chose not to defend his title.
Camilo Ugo Carabelli won the title after defeating Murkel Dellien 6–4, 6–2 in the final.
Thiago Monteiro (semifinals) Francisco Comesaña (second round, withdrew) Camilo Ugo Carabelli (champion) Hugo Dellien (first round) Román Andrés Burruchaga (quarterfinals) Juan Manuel Cerúndolo (quarterfinals) Genaro Alberto Olivieri (second round)
Marco Cecchinato (first round)| Semifinals | Final | ||||||||||||
| 1/WC | Thiago Monteiro | 4 | 5 | ||||||||||
| 3 | Camilo Ugo Carabelli | 6 | 7 | ||||||||||
| 3 | Camilo Ugo Carabelli | 6 | 6 | ||||||||||
| Murkel Dellien | 4 | 2 | |||||||||||
| Murkel Dellien | 6 | 2 | 4 | ||||||||||
| Renzo Olivo | 1 | 6 | 2r | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1/WC | T Monteiro | 6 | 6 | ||||||||||||||||||||||||
| Edoardo Lavagno | 2 | 2 | 1/WC | T Monteiro | 6 | 6 | |||||||||||||||||||||
| Q | V Aboian | 6 | 5 | 6 | Q | V Aboian | 3 | 3 | |||||||||||||||||||
| PR |  P Jubb | 3 | 7 | 3 | 1/WC | T Monteiro | 6 | 6 | |||||||||||||||||||
| M Pucinelli de Almeida | 6 | 6 | P Sakamoto | 1 | 4 | ||||||||||||||||||||||
| A Collarini | 1 | 1 | M Pucinelli de Almeida | 7 | 0 | 4 | |||||||||||||||||||||
| P Sakamoto | 6 | 6 | P Sakamoto | 5 | 6 | 6 | |||||||||||||||||||||
| 8 | M Cecchinato | 4 | 4 | 1/WC | T Monteiro | 4 | 5 | ||||||||||||||||||||
| 3 | C Ugo Carabelli | 712 | 5 | 4 | 3 | C Ugo Carabelli | 6 | 7 | |||||||||||||||||||
| WC |  AD Vallejo | 610 | 7 | 0r | 3 | C Ugo Carabelli | 77 | 6 | |||||||||||||||||||
| FA Gómez | 4 | 0 | WC | JC Prado Ángelo | 63 | 1 | |||||||||||||||||||||
| WC | JC Prado Ángelo | 6 | 6 | 3 | C Ugo Carabelli | 4 | 77 | 6 | |||||||||||||||||||
 G Oliveira | 6 | 6 | G Oliveira | 6 | 61 | 1 | |||||||||||||||||||||
| Alexander Weis | 3 | 3 | G Oliveira | 6 | 6 | ||||||||||||||||||||||
| F Passaro | 2 | 2 | 7 | GA Olivieri | 4 | 2 | |||||||||||||||||||||
| 7 | GA Olivieri | 6 | 6 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 5 | RA Burruchaga | 6 | 6 | ||||||||||||||||||||||||
| Q | Mariano Kestelboim | 2 | 4 | 5 | RA Burruchaga | 712 | 6 | ||||||||||||||||||||
| G Mager | 6 | 6 | G Mager | 610 | 1 | ||||||||||||||||||||||
 G Bueno | 1 | 1 | 5 | RA Burruchaga | 2 | 6 | 4 | ||||||||||||||||||||
 B Bicknell | 6 | 2 | 3 | M Dellien | 6 | 2 | 6 | ||||||||||||||||||||
 L Draxl | 3 | 6 | 6 | L Draxl | 3 | 6 | 5 | ||||||||||||||||||||
| M Dellien | 7 | 6 | M Dellien | 6 | 3 | 7 | |||||||||||||||||||||
| 4 | H Dellien | 5 | 1 | M Dellien | 6 | 2 | 4 | ||||||||||||||||||||
| 6 | JM Cerúndolo | 6 | 6 | R Olivo | 1 | 6 | 2r | ||||||||||||||||||||
| Q | Guido Iván Justo | 3 | 2 | 6 | JM Cerúndolo | 6 | 6 | ||||||||||||||||||||
| Q |  GA Boitan | 6 | 6 | Q | GA Boitan | 3 | 1 | ||||||||||||||||||||
| Q | G Villanueva | 0 | 3 | 6 | JM Cerúndolo | 3 | 64 | ||||||||||||||||||||
| Q | JB Torres | 3 | 1 | R Olivo | 6 | 77 | |||||||||||||||||||||
| R Olivo | 6 | 6 | R Olivo | w/o | |||||||||||||||||||||||
 P Sekulic | 77 | 3 | 1 | 2 | F Comesaña | ||||||||||||||||||||||
| 2 | F Comesaña | 65 | 6 | 6 | |||||||||||||||||||||||
Gastão Elias was the defending champion but lost in the first round to Camilo Ugo Carabelli.
Daniel Elahi Galán was the defending champion, but chose not to defend his title.
Sebastián Báez was the defending champion but chose not to participate.
This was the first edition of the tournament as part of the Legión Sudamericana.
This was the first edition of the tournament.
Francisco Cerúndolo was the defending champion but chose not to defend his title.
Hugo Dellien was the defending champion but chose not to defend his title.
Camilo Ugo Carabelli was the defending champion but chose not to defend his title.
Juan Manuel Cerúndolo was the defending champion and successfully defended his title, defeating Jesper de Jong 6–3, 2–6, 6–2 in the final.
Daniel Elahi Galán was the defending champion but chose not to defend his title.
Sebastián Báez defeated Federico Coria in the final, 6–1, 3–6, 6–3 to win the singles tennis title at the 2023 Córdoba Open.
Hugo Dellien was the defending champion and successfully defended his title after defeating Thiago Seyboth Wild 3–6, 6–3, 6–3 in the final.
Paul Jubb was the defending champion but chose not to defend his title.
Jan Choinski was the defending champion but lost in the second round to Andrea Pellegrino.
Agustín Velotti was the defending champion from when the tournament was last held in 2016 but didn't defend his title as he retired from professional tennis.
Daniel Altmaier was the defending champion but chose not to defend his title.
Facundo Díaz Acosta defeated Nicolás Jarry in the final, 6–3, 6–4 to win the singles tennis title at the 2024 Argentina Open. He did not lose a set en route to his first ATP Tour title and became the first wildcard to win the Argentina Open, as well as the first unseeded player to win the title since Alexandr Dolgopolov in 2017.
Sebastián Báez defeated Mariano Navone in the final, 6–2, 6–1 to win the singles tennis title at the 2024 Rio Open. It was his fifth ATP Tour title and his first ATP 500 title. Navone was the second qualifier to contest the Rio Open final, following Gianluca Mager in 2020.
Sebastián Báez defeated Alejandro Tabilo in the final, 3–6, 6–0, 6–4 to win the singles tennis title at the 2024 Chile Open. It was his sixth career ATP Tour title and his second title in as many weeks, having won the Rio Open the week before.
Hugo Dellien was the defending champion but lost in the quarterfinals to Facundo Bagnis.