Adenylate kinase 3 is a protein that in humans is encoded by the AK3 gene. [5]
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific three-dimensional structure that determines its activity.
In biology, a gene is a sequence of nucleotides in DNA or RNA that codes for a molecule that has a function. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic trait. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes as well as gene–environment interactions. Some genetic traits are instantly visible, such as eye color or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that constitute life.
The protein encoded by this gene is a GTP:ATP phosphotransferase that is found in the mitochondrial matrix. Several transcript variants encoding a few different isoforms have been found for this gene.
The Gs alpha subunit is a heterotrimeric G protein subunit that activates the cAMP-dependent pathway by activating adenylyl cyclase. It is one of the three main families of G proteins: Gαi/Gαo, Gαq, and Gαs. A mnemonic for remembering this subunit is to look at the first letter. In humans it is encoded by the GNAS complex locus.
Fas-activated serine/threonine kinase is an enzyme that in humans is encoded by the FASTK gene.
Adenylate kinase 2 is an enzyme that is encoded in humans by the AK2 gene. The AK2 protein is found in the intermembrane space of the mitochondrion.
Adenylate kinase isoenzyme 4, mitochondrial is an enzyme that in humans is encoded by the AK3L1 gene.
Brain-type creatine kinase also known as CK-BB is a creatine kinase that in humans is encoded by the CKB gene.
Coiled coil domain containing 90B, also known as CCDC90B, is a protein encoded by the CCDC90B gene.
Mitochondrial glycine transporter is a protein that in humans is encoded by the SLC25A38 gene. SLC25A38 is involved in mitochondrial handling of glycine and is needed for the first step in heme synthesis. Mutations in this gene can lead to an autosomal recessive form of sideroblastic anemia.
Mitochondrial ribosomal protein L3 is a protein that in humans is encoded by the MRPL3 gene.
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) is an enzyme in humans that is encoded by the HMGCS2 gene.
Solute carrier family 25, member 16 is a protein in humans that is encoded by the SLC25A16 gene.
A kinase (PRKA) interacting protein 1 is a protein in humans that is encoded by the AKIP1 gene.
Calcium/calmodulin-dependent protein kinase ID is a protein in humans that is encoded by the CAMK1D gene on chromosome 10.
Calcium-binding mitochondrial carrier protein SCaMC-1 is a protein that in humans is encoded by the SLC25A24 gene.
Thymidine kinase 2, mitochondrial is a protein that in humans is encoded by the TK2 gene.
Rho associated coiled-coil containing protein kinase 2 is a protein that in humans is encoded by the ROCK2 gene.
TELO2 interacting protein 2 is a protein that in humans is encoded by the TTI2 gene.
Mitochondrial ribosomal protein L13 is a protein that in humans is encoded by the MRPL13 gene.
Mitogen-activated protein kinase kinase kinase 19 is a protein that in humans is encoded by the MAP3K19 gene.
Mitochondrial ribosomal protein S2 (MRPS2), otherwise known as uS2m, is a protein that in humans is encoded by the MRPS2 gene.
Adenylate kinase 1 is a protein that in humans is encoded by the AK1 gene.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
The United States National Library of Medicine (NLM), operated by the United States federal government, is the world's largest medical library.
The public domain consists of all the creative works to which no exclusive intellectual property rights apply. Those rights may have expired, been forfeited, expressly waived, or may be inapplicable.
This article on a gene on human chromosome 9 is a stub. You can help Wikipedia by expanding it. |