AK3

Last updated
AK3
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases AK3 , AK3L1, AK6, AKL3L, AKL3L1, FIX, adenylate kinase 3
External IDs MGI: 1860835 HomoloGene: 21744 GeneCards: AK3
Gene location (Human)
Ideogram human chromosome 9.svg
Chr. Chromosome 9 (human) [1]
Human chromosome 9 ideogram.svg
HSR 1996 II 3.5e.svg
Red rectangle 2x18.png
Band 9p24.1Start4,709,556 bp [1]
End4,742,043 bp [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_021299
NM_001365071

RefSeq (protein)

NP_001186781
NP_001186782
NP_001186784
NP_001186785
NP_057366

Contents

NP_067274
NP_001352000

Location (UCSC) Chr 9: 4.71 – 4.74 Mb Chr 19: 29.02 – 29.05 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Adenylate kinase 3 is a protein that in humans is encoded by the AK3 gene. [5]

Protein Biological molecule consisting of chains of amino acid residues

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific three-dimensional structure that determines its activity.

Gene Basic physical and functional unit of heredity

In biology, a gene is a sequence of nucleotides in DNA or RNA that codes for a molecule that has a function. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic trait. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes as well as gene–environment interactions. Some genetic traits are instantly visible, such as eye color or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that constitute life.

Function

The protein encoded by this gene is a GTP:ATP phosphotransferase that is found in the mitochondrial matrix. Several transcript variants encoding a few different isoforms have been found for this gene.

Related Research Articles

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Fas-activated serine/threonine kinase is an enzyme that in humans is encoded by the FASTK gene.

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AK3L1 protein-coding gene in the species Homo sapiens

Adenylate kinase isoenzyme 4, mitochondrial is an enzyme that in humans is encoded by the AK3L1 gene.

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SLC25A16 protein-coding gene in the species Homo sapiens

Solute carrier family 25, member 16 is a protein in humans that is encoded by the SLC25A16 gene.

AKIP1 protein-coding gene in the species Homo sapiens

A kinase (PRKA) interacting protein 1 is a protein in humans that is encoded by the AKIP1 gene.

CAMK1D protein-coding gene in the species Homo sapiens

Calcium/calmodulin-dependent protein kinase ID is a protein in humans that is encoded by the CAMK1D gene on chromosome 10.

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Calcium-binding mitochondrial carrier protein SCaMC-1 is a protein that in humans is encoded by the SLC25A24 gene.

Thymidine kinase 2, mitochondrial protein-coding gene in the species Homo sapiens

Thymidine kinase 2, mitochondrial is a protein that in humans is encoded by the TK2 gene.

ROCK2 protein-coding gene in the species Homo sapiens

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TTI2 protein-coding gene in the species Homo sapiens

TELO2 interacting protein 2 is a protein that in humans is encoded by the TTI2 gene.

Mitochondrial ribosomal protein l13 protein-coding gene in the species Homo sapiens

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MAP3K19 protein-coding gene in the species Homo sapiens

Mitogen-activated protein kinase kinase kinase 19 is a protein that in humans is encoded by the MAP3K19 gene.

MRPS2 protein-coding gene in the species Homo sapiens

Mitochondrial ribosomal protein S2 (MRPS2), otherwise known as uS2m, is a protein that in humans is encoded by the MRPS2 gene.

Adenylate kinase 1 protein-coding gene in the species Homo sapiens

Adenylate kinase 1 is a protein that in humans is encoded by the AK1 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000147853 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024782 - Ensembl, May 2017
  3. "Human PubMed Reference:".
  4. "Mouse PubMed Reference:".
  5. "Entrez Gene: Adenylate kinase 3" . Retrieved 2017-05-19.


Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

United States National Library of Medicine Worlds largest medical library

The United States National Library of Medicine (NLM), operated by the United States federal government, is the world's largest medical library.

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