Related Research Articles
Trpc4-associated protein is a protein that in humans is encoded by the TRPC4AP gene.
ARF GTPase-activating protein GIT2 is an enzyme that in humans is encoded by the GIT2 gene.
Centromere protein J is a protein that in humans is encoded by the CENPJ gene. It is also known as centrosomal P4.1-associated protein (CPAP). During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein.
AT-rich interactive domain-containing protein 2 (ARID2) is a protein that in humans is encoded by the ARID2 gene.
Disco-interacting protein 2 homolog A is a protein that in humans is encoded by the DIP2A gene.
Guanine nucleotide exchange factor DBS is a protein that in humans is encoded by the MCF2L gene.
Mitochondrial Rho GTPase 1 (MIRO1) is an enzyme that in humans is encoded by the RHOT1 gene on chromosome 17. As a Miro protein isoform, the protein facilitates mitochondrial transport by attaching the mitochondria to the motor/adaptor complex. Through its key role in mitochondrial transport, RHOT1 is involved in mitochondrial homeostasis and apoptosis, as well as Parkinson’s disease (PD) and cancer.
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 is an enzyme that in humans is encoded by the AGAP1 gene.
RhoU is a small signaling G protein, and is a member of the Rho family of GTPases. Wrch1 was identified in 2001 as encoded by a non-canonical Wnt induced gene. RhoU/Wrch delineates with RhoV/Chp a Rho subclass related to Rac and Cdc42, which emerged in early multicellular organisms during evolution.
Rho-related BTB domain-containing protein 3 is a protein that in humans is encoded by the RHOBTB3 gene.
N-terminal EF-hand calcium-binding protein 2 is a protein that in humans is encoded by the NECAB2 gene.
StAR-related lipid transfer domain protein 13 (STARD13) also known as deleted in liver cancer 2 protein (DLC-2) is a protein that in humans is encoded by the STARD13 gene and a member of the DLC family of proteins.
Rho guanine nucleotide exchange factor 4 is a protein that in humans is encoded by the ARHGEF4 gene.
FERM, RhoGEF and pleckstrin domain-containing protein 2 is a protein that in humans is encoded by the FARP2 gene.
StAR-related lipid transfer domain protein 8 (STARD8) also known as deleted in liver cancer 3 protein (DLC-3) is a protein that in humans is encoded by the STARD8 gene and is a member of the DLC family.
Solute carrier family 41, member 3 is a protein that in humans is encoded by the SLC41A3 gene.
Rho GTPase activating protein 25 is a protein that in humans is encoded by the ARHGAP25 gene. The gene is also known as KAIA0053. ARHGAP25 belongs to a family of Rho GTPase-modulating proteins that are implicated in actin remodeling, cell polarity, and cell migration.
Malignant Brain Tumor domain containing 1 is a protein that in humans is encoded by the MBTD1 gene. The gene is also known as SA49P01.
Transmembrane protein 165 is a protein that in humans is encoded by the TMEM165 gene.
RAB7, member RAS oncogene family-like 1 is a protein that in humans is encoded by the RAB7L1 gene. The gene is also known as RAB7L. RAB7L1 encodes a small GTP-binding protein and is a member of the Ras superfamily.
References
- 1 2 "Rho GTPase activating protein 18" . Retrieved 2011-12-05.
- ↑ Potkin, S. G.; Turner, J. A.; Fallon, J. A.; Lakatos, A.; Keator, D. B.; Guffanti, G.; MacCiardi, F. (2008). "Gene discovery through imaging genetics: Identification of two novel genes associated with schizophrenia". Molecular Psychiatry. 14 (4): 416–428. doi:10.1038/mp.2008.127. PMC 3254586 . PMID 19065146.
- ↑ "Salmonella infection data for Arhgap18". Wellcome Trust Sanger Institute.
- ↑ "Citrobacter infection data for Arhgap18". Wellcome Trust Sanger Institute.
- 1 2 3 4 Gerdin AK (2010). "The Sanger Mouse Genetics Programme: High throughput characterisation of knockout mice". Acta Ophthalmologica. 88: 925–7. doi:10.1111/j.1755-3768.2010.4142.x. S2CID 85911512.
- ↑ Mouse Resources Portal, Wellcome Trust Sanger Institute.
- ↑ "International Knockout Mouse Consortium".
- ↑ "Mouse Genome Informatics".
- ↑ Skarnes, W. C.; Rosen, B.; West, A. P.; Koutsourakis, M.; Bushell, W.; Iyer, V.; Mujica, A. O.; Thomas, M.; Harrow, J.; Cox, T.; Jackson, D.; Severin, J.; Biggs, P.; Fu, J.; Nefedov, M.; De Jong, P. J.; Stewart, A. F.; Bradley, A. (2011). "A conditional knockout resource for the genome-wide study of mouse gene function". Nature. 474 (7351): 337–342. doi:10.1038/nature10163. PMC 3572410 . PMID 21677750.
- ↑ Dolgin E (2011). "Mouse library set to be knockout". Nature. 474 (7351): 262–3. doi: 10.1038/474262a . PMID 21677718.
- ↑ Collins FS, Rossant J, Wurst W (2007). "A Mouse for All Reasons". Cell. 128 (1): 9–13. doi: 10.1016/j.cell.2006.12.018 . PMID 17218247. S2CID 18872015.
- ↑ van der Weyden L, White JK, Adams DJ, Logan DW (2011). "The mouse genetics toolkit: revealing function and mechanism". Genome Biol. 12 (6): 224. doi:10.1186/gb-2011-12-6-224. PMC 3218837 . PMID 21722353.
