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Company type | Clinical laboratory |
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Genre | Corporate histories |
Founded | 1984 in Salt Lake City, Utah |
Founders | Carl Kjeldsberg, John Matsen |
Headquarters | , |
Key people | |
Number of employees | 4,000 |
Website | www.aruplab.com |
Associated Regional and University Pathologists, Inc. (ARUP Laboratories) is a Salt Lake City, Utah-based nonprofit laboratory at University of Utah's Department of Pathology. It is located in the University of Utah Research Park and provides national research lab services. ARUP has 4,000 employees and 65 laboratories. [1]
ARUP was founded by John Matsen and Carl Kjeldsberg, based on Lloyd Martin's vision of an independent, not-for-profit laboratory owned by the Department of Pathology. [2]
ARUP's facilities operate with a high degree of automation. Their 65 laboratories include sorters, automated thawing and mixing, and house a two-story automated lab specimen freezer. The freezer can store 2.3 million specimens and retrieve a specimen in 2.5 minutes. [3]
In 2003, ARUP partnered with the Utah Department of Health to create a pilot program for expanding newborn screening in Utah to include an additional 30 metabolic markers. A year later, this program became the standard for the mandatory screening of all newborns in the state of Utah. [4]
Anatomical pathology (Commonwealth) or anatomic pathology (U.S.) is a medical specialty that is concerned with the diagnosis of disease based on the macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues. Over the 20th century, surgical pathology has evolved tremendously: from historical examination of whole bodies (autopsy) to a more modernized practice, centered on the diagnosis and prognosis of cancer to guide treatment decision-making in oncology. Its modern founder was the Italian scientist Giovanni Battista Morgagni from Forlì.
Clinical chemistry is a division in medical laboratory sciences focusing on qualitative tests of important compounds, referred to as analytes or markers, in bodily fluids and tissues using analytical techniques and specialized instruments. This interdisciplinary field includes knowledge from medicine, biology, chemistry, biomedical engineering, informatics, and an applied form of biochemistry.
Newborn screening (NBS) is a public health program of screening in infants shortly after birth for conditions that are treatable, but not clinically evident in the newborn period. The goal is to identify infants at risk for these conditions early enough to confirm the diagnosis and provide intervention that will alter the clinical course of the disease and prevent or ameliorate the clinical manifestations. NBS started with the discovery that the amino acid disorder phenylketonuria (PKU) could be treated by dietary adjustment, and that early intervention was required for the best outcome. Infants with PKU appear normal at birth, but are unable to metabolize the essential amino acid phenylalanine, resulting in irreversible intellectual disability. In the 1960s, Robert Guthrie developed a simple method using a bacterial inhibition assay that could detect high levels of phenylalanine in blood shortly after a baby was born. Guthrie also pioneered the collection of blood on filter paper which could be easily transported, recognizing the need for a simple system if the screening was going to be done on a large scale. Newborn screening around the world is still done using similar filter paper. NBS was first introduced as a public health program in the United States in the early 1960s, and has expanded to countries around the world.
Texas A&M Veterinary Medical Diagnostic Laboratory (TVMDL) is an integral part of the Texas A&M University System. It consists of four lab locations spread across Texas; two full-service laboratories located in Canyon and College Station and two poultry laboratories in Center and Gonzales.
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The Association of Public Health Laboratories (APHL) is a membership organization in the United States representing the laboratories that protect the health and safety of the public. APHL serves as a liaison between public health laboratories and federal and international agencies. Membership consists of local, state, county, and territorial public health laboratories; public health environmental, agricultural and veterinary laboratories; and corporations and individuals with an interest in public health and laboratory science. APHL is a non-profit, 501(c)(3) organization with a history of over fifty years.
The State University of New York Upstate Medical University is a public medical school in Syracuse, New York. Founded in 1834, Upstate is the 15th oldest medical school in the United States and is the only medical school in Central New York. The university is part of the State University of New York (SUNY) system.
James Linder is an American author, academic and businessperson, as well as an authority on university research commercialization. He serves as chief executive officer (CEO) of Nebraska Medicine, and most recently was president of the University Technology Development Corporation and chief strategist for the University of Nebraska system. He is also a professor of pathology and microbiology at the University of Nebraska Medical Center.
A medical laboratory or clinical laboratory is a laboratory where tests are conducted out on clinical specimens to obtain information about the health of a patient to aid in diagnosis, treatment, and prevention of disease. Clinical medical laboratories are an example of applied science, as opposed to research laboratories that focus on basic science, such as found in some academic institutions.
Laboratory Corporation of America Holdings, more commonly known as Labcorp, is an American healthcare company headquartered in Burlington, North Carolina. It operates one of the largest clinical laboratory networks in the world, with a United States network of 36 primary laboratories. Before a merger with National Health Laboratory in 1995, the company operated under the name Roche BioMedical. Labcorp performs its largest volume of specialty testing at its Center for Esoteric Testing in Burlington, North Carolina, where the company is headquartered. As of 2018, Labcorp processes 2.5 million lab tests weekly.
Rodney Smith Markin, is an American pathologist and authority in the field of laboratory automation. In 1993, he designed and created one of the world's first automated clinical laboratory specimen, device and analyzer management systems. In the mid-1990s, he chaired a standards group called the Clinical Testing Automation Standards Steering Committee (CTASSC) of the American Association for Clinical Chemistry, which later evolved into an area committee of the Clinical and Laboratory Standards Institute.
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The Oregon PHL/DEQ Laboratories are the Oregon Department of Environmental Quality (DEQ) and Oregon Department of Human Services (DHS) laboratories located in a single building in Hillsboro, Oregon, United States. DHS operates the Oregon State Public Health Laboratory (OSPHL), and the DEQ operates their Laboratory and Environmental Assessment Division at the site. The laboratories previously were located at Portland State University, moving to the new location near Cornelius Pass Road and the Sunset Highway in northeast Hillsboro in 2007.
Universal neonatal hearing screening (UNHS), which is part of early hearing detection and intervention (EHDI) programmes, refer to those services aimed at screening hearing of all newborns, regardless of the presence of a risk factor for hearing loss. UNHS is the first step in the EHDI program which indicates whether a newborn requires further audiological assessment to determine the presence or absence of permanent hearing loss. Newborn hearing screening uses objective testing methods to screen the hearing of all newborns in a particular target region, regardless of the presence or absence of risk factors. Even among developed countries, until the 1990s, it could take years for hearing-impaired child to be diagnosed and to benefit from a health intervention and amplification. This delay still can happen in developing countries. If children are not exposed to sounds and language during their first years of life because of a hearing loss, they will have difficulty in developing spoken or signed language; cognitive development and social skills could also be affected. This screening separates children into two groups—those with a high index of suspicion and those with a low index of suspicion. Those in the first group are referred for diagnostic testing.
President George W. Bush signed the Newborn Screening Saves Lives Act of 2007 (Pub.L.110-204) (NBSSLA) into law on April 24, 2008, a day before DNA Day. The Act amended the Public Health Service Act to establish grant programs concerning newborn screening education and outreach, as parents are often unaware that newborn screening takes place and the number and types of screening varies across states. It also established grant programs to coordinate follow-up care, after newborn screening is conducted. The legislation also reauthorized programs under part A of title XI of the Public Health Service Act. In his introductory remarks, Senator Chris Dodd stated that the legislation "protect[s] the most vulnerable members of our society: newborn infants." Newborn Screening is a proven life saving and effective public health tool used to identify thousands of babies in the U.S. born with genetic, metabolic, and congenital conditions. At the time of the legislation's passage, only 15 States along with the District of Columbia required newborns to be screened for 29 core conditions as recommended by the Health Resources and Services Administration/American College of Medical Genetics' 2004 Report.
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