Adenoviral keratoconjunctivitis

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Keratoconjunctivitis
Other namesKeratoconjunctivitis epidemica
Keratoconjunctivitis epidemica 2.jpg
Adenoviral Keratoconjunctivitis
Specialty Ophthalmology, infectious diseases
Symptoms Red eye, discomfort/irritation, sensitivity to light, watering, blurred vision, discharge [1]
Complications Corneal scarring [2]
Usual onsetSudden in an adult [3]
Duration7–10 days, can be longer [3]
Causes Adenoviruses , commonly types 8 and 37 [3]
Diagnostic method Visualisation, viral culture (with immunofluorescence staining), PCR (to detect viral DNA) [3]
Differential diagnosis Herpes simplex type I, acanthamoeba, fungal infection [4]
Prevention Hand washing [3]
TreatmentCold compress, artificial tears [2]
FrequencyEpidemics, common, adults>children [2]

Adenoviral keratoconjunctivitis, also known as epidemic keratoconjunctivitis, is a contagious eye infection, a type of adenovirus disease caused by adenoviruses . [1] It typically presents as a conjunctivitis with a sudden onset of a painful red eye, watery discharge and feeling that something is in the eye. [3] Photophobia develops with blurred vision and lymphadenopathy by the ear nearest the affected eye. [2] It is often associated with a sore throat and stuffy and runny nose, mainly in adults. [3] A type of adenoviral keratoconjunctivitis in very young children can present with a high fever, sore throat, ear infection, vomiting and diarrhea. [3]

Contents

It is commonly caused by types 8 and 37 adenoviruses , spread by contaminated eye examination instruments and eye solutions, touching eyes by infected people, from inadequately chlorinated swimming pools, or other contaminated objects. [3] The incubation period is around five to 10 days. [3]

Usually, the condition is better after a week to 10 days without treatment. [3] Cold compresses and artificial tears may help. [2] Corneal scarring occurs in up to half of cases and the blurred vision may continue for a long time in some people. [2] The virus may remain in the eye for 2–3 years after recovering. [3]

It is a common cause of a red eye and tends to occur in large numbers of people at the same time. [2] Adults tend to be affected more frequently than children. [3]

Signs and symptoms

It typically presents as a conjunctivitis with a sudden onset of red eye, watery discharge and feeling that something is in the eye. [3] Photophobia develops with blurred vision and lymphadenopathy by the ear nearest the affected eye. [2] It is typically associated with a pharyngitis and rhinitis, mainly in adults. [3] A type of adenoviral keratoconjunctivitis in very young children can present with a high fever, sore throat, ear infection, vomiting and diarrhea. [3]

Diagnosis

The diagnosis of Adenoviral keratoconjunctivitis is done using cell culture (with immunofluorescence staining) and PCR. [4]

Differential diagnosis

It may appear similar to herpes simplex type I, Acanthamoeba , and fungal infection. [4]

Prevention

Adequate infection control measures should be followed as prevention and to reduce epidemic AKC outbreaks. [5]

Treatment

Epidemiology

Globally it is the commonest cause of a red eye and tends to occur in large numbers of people at the same time. [2] Adults tend to be affected more frequently than children. [3]

References

  1. 1 2 Burrow, Michael K.; Patel, Bhupendra C. (2022). "Keratoconjunctivitis". StatPearls. StatPearls Publishing. PMID   31194419.
  2. 1 2 3 4 5 6 7 8 9 Bawazeer, Ahmed (4 June 2019). "Epidemic Keratoconjunctivitis (EKC)" . Medscape. Archived from the original on 21 April 2021. Retrieved 16 July 2021.
  3. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 Shieh, Wun-Ju (10 September 2021). "Human adenovirus infections in pediatric population - An update on clinico-pathologic correlation". Biomedical Journal. 45 (1): S2319–4170(21)00109–8. doi:10.1016/j.bj.2021.08.009. ISSN   2320-2890. PMC   9133246 . PMID   34506970. S2CID   237479412.
  4. 1 2 3 Pihos, Andria M. (April 2013). "Epidemic keratoconjunctivitis: A review of current concepts in management". Journal of Optometry. 6 (2): 69–74. doi:10.1016/j.optom.2012.08.003. ISSN   1888-4296. PMC   3880539 .
  5. Reinhard, Thomas; Larkin, Frank (28 January 2006). Cornea and External Eye Disease. Springer. ISBN   9783540312260. Archived from the original on 11 January 2023. Retrieved 22 March 2015.