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Magnetoencephalography (MEG) is a functional neuroimaging technique for mapping brain activity by recording magnetic fields produced by electrical currents occurring naturally in the brain, using very sensitive magnetometers. Arrays of SQUIDs are currently the most common magnetometer, while the SERF magnetometer is being investigated for future machines. Applications of MEG include basic research into perceptual and cognitive brain processes, localizing regions affected by pathology before surgical removal, determining the function of various parts of the brain, and neurofeedback. This can be applied in a clinical setting to find locations of abnormalities as well as in an experimental setting to simply measure brain activity.
Functional neuroimaging is the use of neuroimaging technology to measure an aspect of brain function, often with a view to understanding the relationship between activity in certain brain areas and specific mental functions. It is primarily used as a research tool in cognitive neuroscience, cognitive psychology, neuropsychology, and social neuroscience.
Functional integration is the study of how brain regions work together to process information and effect responses. Though functional integration frequently relies on anatomic knowledge of the connections between brain areas, the emphasis is on how large clusters of neurons – numbering in the thousands or millions – fire together under various stimuli. The large datasets required for such a whole-scale picture of brain function have motivated the development of several novel and general methods for the statistical analysis of interdependence, such as dynamic causal modelling and statistical linear parametric mapping. These datasets are typically gathered in human subjects by non-invasive methods such as EEG/MEG, fMRI, or PET. The results can be of clinical value by helping to identify the regions responsible for psychiatric disorders, as well as to assess how different activities or lifestyles affect the functioning of the brain.
Neural oscillations, or brainwaves, are rhythmic or repetitive patterns of neural activity in the central nervous system. Neural tissue can generate oscillatory activity in many ways, driven either by mechanisms within individual neurons or by interactions between neurons. In individual neurons, oscillations can appear either as oscillations in membrane potential or as rhythmic patterns of action potentials, which then produce oscillatory activation of post-synaptic neurons. At the level of neural ensembles, synchronized activity of large numbers of neurons can give rise to macroscopic oscillations, which can be observed in an electroencephalogram. Oscillatory activity in groups of neurons generally arises from feedback connections between the neurons that result in the synchronization of their firing patterns. The interaction between neurons can give rise to oscillations at a different frequency than the firing frequency of individual neurons. A well-known example of macroscopic neural oscillations is alpha activity.
Social neuroscience is an interdisciplinary field devoted to understanding the relationship between social experiences and biological systems. Humans are fundamentally a social species, rather than solitary. As such, Homo sapiens create emergent organizations beyond the individual—structures that range from dyads, families, and groups to cities, civilizations, and cultures. In this regard, studies indicate that various social influences, including life events, poverty, unemployment and loneliness can influence health related biomarkers. The term "social neuroscience" can be traced to a publication entitled "Social Neuroscience Bulletin" which was published quarterly between 1988 and 1994. The term was subsequently popularized in an article by John Cacioppo and Gary Berntson, published in the American Psychologist in 1992. Cacioppo and Berntson are considered as the legitimate fathers of social neuroscience. Still a young field, social neuroscience is closely related to personality neuroscience, affective neuroscience and cognitive neuroscience, focusing on how the brain mediates social interactions. The biological underpinnings of social cognition are investigated in social cognitive neuroscience.
Neuroimaging is the use of quantitative (computational) techniques to study the structure and function of the central nervous system, developed as an objective way of scientifically studying the healthy human brain in a non-invasive manner. Increasingly it is also being used for quantitative research studies of brain disease and psychiatric illness. Neuroimaging is highly multidisciplinary involving neuroscience, computer science, psychology and statistics, and is not a medical specialty. Neuroimaging is sometimes confused with neuroradiology.
The Cognition and Brain Sciences Unit is a branch of the UK Medical Research Council, based in Cambridge, England. The CBSU is a centre for cognitive neuroscience, with a mission to improve human health by understanding and enhancing cognition and behaviour in health, disease and disorder. It is one of the largest and most long-lasting contributors to the development of psychological theory and practice.
Olli Viktor Lounasmaa was a Finnish academician, experimental physicist and neuroscientist. He was known for his research in low temperature physics, especially for experimental proof of the superfluidity of helium-3 and also for his work in the field of magnetoencephalography.
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Neurophysics is the branch of biophysics dealing with the development and use of physical methods to gain information about the nervous system. Neurophysics is an interdisciplinary science using physics and combining it with other neurosciences to better understand neural processes. The methods used include the techniques of experimental biophysics and other physical measurements such as EEG mostly to study electrical, mechanical or fluidic properties, as well as theoretical and computational approaches. The term "neurophysics" is a portmanteau of "neuron" and "physics".
Electroencephalography (EEG) is a method to record an electrogram of the spontaneous electrical activity of the brain. The biosignals detected by EEG have been shown to represent the postsynaptic potentials of pyramidal neurons in the neocortex and allocortex. It is typically non-invasive, with the EEG electrodes placed along the scalp using the International 10–20 system, or variations of it. Electrocorticography, involving surgical placement of electrodes, is sometimes called "intracranial EEG". Clinical interpretation of EEG recordings is most often performed by visual inspection of the tracing or quantitative EEG analysis.
Bin He is a Chinese American biomedical engineering scientist. He is the Trustee Professor of the Department of Biomedical Engineering, professor by courtesy in the Department of Electrical and Computer Engineering, and Professor of Neuroscience Institute, and was the head of the department of Biomedical Engineering at Carnegie Mellon University. Prior, he was Distinguished McKnight University Professor of Biomedical Engineering and Medtronic-Bakken Endowed Chair for Engineering in Medicine at the University of Minnesota. He previously served as the director of the Institute for Engineering in Medicine and the Center for Neuroengineering at the University of Minnesota. He was the Editor in Chief of the IEEE Transactions on Biomedical Engineering and serves as the editor in chief of IEEE Reviews in Biomedical Engineering. He was the president of the IEEE Engineering in Medicine & Biology Society (EMBS) from 2009 to 2010 and chair of International Academy of Medical and Biological Engineering from 2018 to 2021.
The Human Connectome Project (HCP) is a five-year project sponsored by sixteen components of the National Institutes of Health, split between two consortia of research institutions. The project was launched in July 2009 as the first of three Grand Challenges of the NIH's Blueprint for Neuroscience Research. On September 15, 2010, the NIH announced that it would award two grants: $30 million over five years to a consortium led by Washington University in St. Louis and the University of Minnesota, with strong contributions from University of Oxford (FMRIB) and $8.5 million over three years to a consortium led by Harvard University, Massachusetts General Hospital and the University of California Los Angeles.
Anders Martin Dale is a prominent neuroscientist and professor of radiology, neurosciences, psychiatry, and cognitive science at the University of California, San Diego (UCSD), and is one of the world's leading developers of sophisticated computational neuroimaging techniques. He is the founding Director of the Center for Multimodal Imaging Genetics (CMIG) at UCSD.
Pedro Antonio Valdes-Sosa is a Cuban neuroscientist who currently serves as the General Vice-Director for Research of the Cuban Neurosciences Center, which he cofounded in 1990. Valdes-Sosa is also member of the editorial boards of journals Neuroimage, Medicc, Audiology and Neurotology, PLosOne and Frontiers, Neuroimage and Brain Connectivity. His work includes statistical analysis of electrophysiological measurements, neuroimaging, nonlinear dynamical modeling of brain functions and Software and electrophysiological equipment development.
Karl John Friston FRS FMedSci FRSB is a British neuroscientist and theoretician at University College London. He is an authority on brain imaging and theoretical neuroscience, especially the use of physics-inspired statistical methods to model neuroimaging data and other random dynamical systems. Friston is a key architect of the free energy principle and active inference. In imaging neuroscience he is best known for statistical parametric mapping and dynamic causal modelling. Friston also acts as a scientific advisor to numerous groups in industry.
Arno Villringer is a Director at the Department of Neurology at the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig, Germany; Director of the Department of Cognitive Neurology at University of Leipzig Medical Center; and Academic Director of the Berlin School of Mind and Brain and the Mind&Brain Institute, Berlin. He holds a full professorship at University of Leipzig and an honorary professorship at Charité, Humboldt-Universität zu Berlin. From July 2022 to June 2025 he is the Chairperson of the Human Sciences Section of the Max Planck Society.
The following outline is provided as an overview of and topical guide to brain mapping:
Riitta Kyllikki Hari is a Finnish neuroscientist, physician and professor at Aalto University. She has led the Brain Research Unit at the Low Temperature Laboratory since 1982. Hari was appointed as Academician of Science on 26 November 2010.
Gina Rippon is a British neurobiologist and feminist. She is a professor emeritus of cognitive neuroimaging at the Aston Brain Centre, Aston University, Birmingham. Rippon has also sat on the editorial board of the International Journal of Psychophysiology. In 2019, Rippon published her book, Gendered Brain: The New Neuroscience that Shatters the Myth of the Female Brain, which investigates the role of life experiences and biology in brain development.
References
- ↑ Puce, A.; Perrett, D. (29 March 2003). "Electrophysiology and brain imaging of biological motion". Philosophical Transactions of the Royal Society B: Biological Sciences. 358 (1431): 435–445. doi:10.1098/rstb.2002.1221. PMC 1693130 . PMID 12689371.
- 1 2 Hari, Riitta; Puce, Aina (2017). MEG-EEG primer. ISBN 978-0190497774.
- ↑ "Editorial Board". NeuroImage. 184: ii. January 2019. doi:10.1016/S1053-8119(18)32043-3.
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