Alash'le Abimiku

Last updated

Alash'le Abimiku
Born
Alash'le Grace Abimku

Alma mater Ahmadu Bello University
London School of Hygiene & Tropical Medicine (PhD)
Known for Retrovirology
Scientific career
Institutions University of Maryland School of Medicine
Institute of Human Virology Nigeria
Thesis Protection against Campylobacter jejuni infection  (1988)
Website www.medschool.umaryland.edu/profiles/Abimiku-Alashle/

Alash'le Grace Abimiku is a Nigerian executive director of the International Research Centre of Excellence at the Institute of Human Virology Nigeria and a professor of virology at the University of Maryland School of Medicine who takes interest in the prevention and treatment of HIV. [1]

Contents

Early life and education

Abimiku was born in Nigeria. She studied microbiology at Ahmadu Bello University. She moved to the London School of Hygiene & Tropical Medicine for her graduate studies, earning a master's degree in 1983 and a PhD in 1998. [2] [3] Here she specialised in retrovirology and protection against infection caused by the bacteria Campylobacter jejuni . [4]

Research and career

After earning her doctorate, Abimiku worked as postdoctoral researcher with Robert Gallo at the National Cancer Institute, where she developed collaborations between scientists in her home country of Nigeria and researchers at the University of Maryland School of Medicine.

She was one the founders that helped in the establishment of the IHVN Campus project in 2004 with IHVN partnering with the Institute of Human Virology at the University of Maryland School of Medicine in the United States. [5]

Gallo and Abimiku opened the International Center for Scientific Culture—World Laboratory AIDS Research Center in Jos. [3] Whilst Abimiku had planned to isolate a particular strain of HIV, she found she had to concentrate on basic screening and community education. Eventually, she studied the HIV strain that is prevalent in Nigeria; identifying that it was the non-B subtype related to the HIV subtype G. [6] [7] Abimiku called for African strains to be included in AIDS Vaccine studies. [8] In 2004 she helped to establish a partnership with Nigeria using funding from the President's Emergency Plan for AIDS Relief (PEPFAR). [9] Abimiku studies the role of HIV in disease pathogenesis and the effects of tuberculosis (TB) and HIV co-infection. She has considered the molecular epidemiology and evolution of subtypes and resistance of HIV, the development of cohorts for HIV epidemiological studies and the epidemiology of selected viruses. [10]

People in Nigeria are most likely to suffer more from this TB and HIV in the world, which makes them more likely to suffer from multi-drug-resistant tuberculosis (MDR-TB), an airborne disease. [9] In 2010 Abimiku and the Institute of Human Virology Nigeria opened a Biosafety Level-3 laboratory, the first of its kind in Africa, to research the prevalence of MDR-TB. The laboratory, which is containerised with pre-filters to withstand the dry and dusty winds can also assess for extremely drug-resistant TB (XDRTB). It includes a negatively pressurised laboratory that allows for the handling of infectious agents. [9] This laboratory supported the UNAIDS 90-90-90 targets and early diagnosis. [11]

In 2012 Abimiku developed an International Society for Biological and Environmental Repositories (IBSER) repository [12] that can process and store biological samples. [13] [14] The repository was supported by the National Institutes of Health Human Heredity and Health in Africa (H3 Africa) program, which was initiated by Charles Rotimi. [14]

She has been involved with the PEPFAR transition to a situation where local governments and indigenous organisations are responsible for caring for d individuals. [15] The Institute of Human Virology Nigeria is acting to support the move toward local ownership. [15] In 2018 she co-founded the International Research Centre of Excellence located in the Institute of Human Virology Nigeria. [16] The centre will focus on building the capacity of African scientists as well as supporting research that affects the country. [16]


Academic service

Abimiku is a member of the advisory group of the University of Cape Town and the World Health Organization Research and Development Blueprint. [17] She served as the chair of the board of the African Society of Laboratory Medicine, as well as a member of the board of the Nigerian Institute of Medical Research. [18] [19] [20] She previously served on the World Health Organization HIV vaccine advisory committee and AIDS Vaccine program. [21] She serves on the Wellcome Trust Longitudinal Population Studies Committee. [22]

Selected publications

Her publications include;

Related Research Articles

<span class="mw-page-title-main">HIV/AIDS in Africa</span>

HIV/AIDS originated in the early 20th century and has become a major public health concern and cause of death in many countries. AIDS rates varies significantly between countries, with the majority of cases concentrated in Southern Africa. Although the continent is home to about 15.2 percent of the world's population, more than two-thirds of the total population infected worldwide – approximately 35 million people – were Africans, of whom around 1 million have already died. Eastern and Southern Africa alone accounted for an estimate of 60 percent of all people living with HIV and 100 percent of all AIDS deaths in 2011. The countries of Eastern and Southern Africa are most affected, leading to raised death rates and lowered life expectancy among adults between the ages of 20 and 49 by about twenty years. Furthermore, life expectancy in many parts of Africa is declining, largely as a result of the HIV/AIDS epidemic, with life-expectancy in some countries reaching as low as thirty-nine years.

The National Institute of Allergy and Infectious Diseases is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's mission is to conduct basic and applied research to better understand, treat, and prevent infectious, immunologic, and allergic diseases.

<span class="mw-page-title-main">Tropical medicine</span> Interdisciplinary branch of medicine

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The European and Developing Countries Clinical Trials Partnership (EDCTP) is a partnership between the European Union (EU), Norway, Switzerland and developing countries and other donors, as well as the pharmaceutical industry, to enable clinical trials and the development of new medicines and vaccines against HIV/AIDS, tuberculosis, and malaria. The need for global action against these diseases in order to promote poverty reduction has been recognised by the United Nations, the G8, and the African Union, and the program envisioned the provision of €600 million for the period 2003–2007 in order to translate medical research results into clinical applications relevant to the needs of developing countries.

<span class="mw-page-title-main">Robert Gallo</span> American biomedical researcher

Robert Charles Gallo is an American biomedical researcher. He is best known for his role in establishing the human immunodeficiency virus (HIV) as the infectious agent responsible for acquired immune deficiency syndrome (AIDS) and in the development of the HIV blood test, and he has been a major contributor to subsequent HIV research.

<span class="mw-page-title-main">Vaccine Research Center</span>

The Vaccine Research Center (VRC), is an intramural division of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), US Department of Health and Human Services (HHS). The mission of the VRC is to discover and develop both vaccines and antibody-based products that target infectious diseases.

Thumbi Ndung’u is a Kenyan-born HIV/AIDS researcher. He is the deputy director (Science) and a Max Planck Research Group Leader at the Africa Health Research Institute (AHRI) in Durban, South Africa. He is Professor of Infectious Diseases in the Division of Immunity and Infection, University College London. He is Professor and Victor Daitz Chair in HIV/TB Research and Scientific Director of the HIV Pathogenesis Programme (HPP) at the Nelson R. Mandela School of Medicine, University of KwaZulu-Natal. He holds the South African Research Chair in Systems Biology of HIV/AIDS. He is an Adjunct Professor of Immunology and Infectious Diseases at the Harvard T.H. Chan School of Public Health. He is the Programme Director of the Sub-Saharan African Network for TB/HIV Research Excellence (SANTHE), a research and capacity building initiative funded by the African Academy of Sciences and the Wellcome Trust.

Deborah Persaud is a Guyanese-born American virologist who primarily works on HIV/AIDS at Johns Hopkins Children's Center.

<span class="mw-page-title-main">Salim Abdool Karim</span> South African medical researcher

Salim S. Abdool Karim, MBChB, MMed, MS(Epi), FFPHM, FFPath (Virol), DipData, PhD, DSc(hc), FRS is a South African public health physician, epidemiologist and virologist who has played a leading role in the AIDS and COVID-19 pandemic. His scientific contributions have impacted the landscape of HIV prevention and treatment, saving thousands of lives.

Harriet Mayanja-Kizza, MBChB, MMed, MSc, FACP, is a Ugandan physician, researcher, and academic administrator. She is the former Dean of Makerere University School of Medicine, the oldest medical school in East Africa, established in 1924.

The Institute of Human Virology Nigeria (IHVN) is a non-governmental organization that focuses on HIV/AIDS related problems in Nigeria. It was established as an affiliate to the Institute of Human Virology, University of Maryland School of Medicine, Baltimore in 2004. In 2016, IHVN claimed that it reaches 2.3 million Nigerians with HIV testing services, including about 25,000 who tested positive for the disease.

William A. Blattner is an American virologist and physician known for his pioneering studies on the epidemiology of human retroviruses. He is a professor of medicine at the University of Maryland School of Medicine, where he co-founded the Institute of Human Virology (IHV) with Robert Gallo and Robert R. Redfield in 1996. He subsequently helped found the Institute of Human Virology, Nigeria, which has screened over 1 million Nigerians for HIV/AIDS. He retired from his position as associate director of the IHV and director of its Division of Epidemiology and Prevention on January 31, 2016. He is also the founding editor-in-chief of the Journal of Acquired Immune Deficiency Syndromes, and serves as its co-editor-in-chief along with Paul A. Volberding.

Caroline Tiemessen is a virologist and researcher involved in HIV related research. She heads the Cell Biology Research Laboratory within the Centre for HIV and STIs at the National Institute for Communicable Diseases and is a research Professor in the School of Pathology at the University of the Witwatersrand (WITS). Her research interests include the study of HIV vaccines and the search for an HIV cure in both children and adults. In 2018 she was part of the research team involved with the transplantation of a liver from an HIV-positive woman to her HIV-negative child.

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<span class="mw-page-title-main">Linda-Gail Bekker</span> Zimbabwean physician & academic

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Pontiano Kaleebu is a Ugandan physician, clinical immunologist, HIV/AIDS researcher, academic and medical administrator, who is the executive director of the Uganda Virus Research Institute.

Roy D. Mugerwa was a Ugandan physician, cardiologist and researcher. His contribution to the world of academics include being a Professor Emeritus at Makerere University College of Health Sciences in Kampala, cardiology in Uganda, researching HIV/AIDS and tuberculosis, and his efforts to find an effective HIV vaccine.

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References

  1. Online, The Eagle (10 August 2017). "How HIV positive mothers can breastfeed exclusively —Director |". The Eagle Online. Retrieved 7 November 2023.
  2. Abimiku, Alash'le Grace (1988). Protection against Campylobacter jejuni infection. london.ac.uk (PhD thesis). University of London. OCLC   940318607.
  3. 1 2 Science, American Association for the Advancement of (28 May 2004). "News this Week". Science. 304 (5675): 180. ISSN   0036-8075.
  4. "Dr. Alash'le G Abimiku". H3Africa. Retrieved 5 October 2019.
  5. "US Varsity, IHVN Launch Research Institute on Healthcare - THISDAYLIVE". www.thisdaylive.com. Retrieved 7 November 2023.
  6. "Prof. Alash'le Abimiku, Mon – IRCE". Archived from the original on 5 October 2019. Retrieved 5 October 2019.
  7. "Reagent Datasheet Detail: Catalog 3191 - HIV-1 Jv1083 Virus - NIH AIDS Reagent Program". aidsreagent.org. Retrieved 5 October 2019.
  8. "AIDS in Africa: AIDS vaccine 'may not work' in Africa". newscientist.com. Retrieved 5 October 2019.
  9. 1 2 3 Abimiku, Alash'le (2010). "IHV and Nigeria Partner with the U.S. to Combat Multi-Drug Resistant Tuberculosis from West Baltimore to West Africa" (PDF). IHV. Retrieved 5 January 2019.
  10. bonbon. "Alash'le Abimiku". FAIS Legacy Project. Retrieved 5 October 2019.
  11. "Abimiku, Alash'le | University of Maryland School of Medicine". medschool.umaryland.edu. Retrieved 5 October 2019.
  12. Abimiku, Alash'le G.; Croxton, Talishea; Ozumba, Petronilla J.; Agala, Ndidi; Balogun, Olasinbo; Jonathan, Emmanuel; Onyemata, Enzenwa; Ndifon, Kachimi; Nadoma, Sunji; Anazodo, Thankgod; Peters, Sam (2019). "Blueprint for building a biorepository in a resource-limited setting that follows international best practices". African Journal of Laboratory Medicine. 8 (1): 12. doi:10.4102/ajlm.v8i1.722. ISSN   2225-2010. PMC   6739520 . PMID   31534913.
  13. "IHVN H3 Africa Biorepository Initiative". Grantome. 1 August 2013. Retrieved 26 June 2024.
  14. 1 2 "Dr. Alash'le Abimiku receives grant to develop H3 Africa bio repository at IHVN". ihvnigeria.org. Archived from the original on 5 October 2019. Retrieved 5 October 2019.
  15. 1 2 "Spotlight on Prof. Alash'le Abimiku, Nigeria". ASLM. Retrieved 5 October 2019.
  16. 1 2 Akor, Ojoma (24 July 2018). "Virology institute establishes research centre in Abuja". dailytrust.com.ng. Archived from the original on 5 October 2019. Retrieved 5 October 2019.
  17. "WHO | Scientific Advisory Group members". who.int. Retrieved 5 October 2019.
  18. "WHO | Alash'le Abimiku". who.int. Retrieved 5 October 2019.
  19. "Professor Alash'le Abimiku elected Chair of the Board of Directors of ASLM". ASLM. Retrieved 5 October 2019.
  20. "NIMR inaugurates advisory board on research funding". thenationonlineng.net. The Nation Newspaper. 28 December 2017. Retrieved 5 October 2019.
  21. Admin, ASLM. "ASLM2018 Conference Chair: Prof Alash'le Abimiku". ASLM2018. Retrieved 5 October 2019.
  22. "Longitudinal Population Studies Committee | Wellcome". wellcome.ac.uk. Retrieved 5 October 2019.
  23. Abimiku, Alash'le (2011). "Laboratory diagnosis of tuberculosis in resource-poor countries: challenges and opportunities". Clinical Microbiology Reviews. 24 (2): 314–350. doi:10.1128/CMR.00059-10. PMC   3122496 . PMID   21482728.
  24. Abimiku, Alash'le (2010). "Patient Retention and Adherence to Antiretrovirals in a Large Antiretroviral Therapy Program in Nigeria: A Longitudinal Analysis for Risk Factors". PLOS ONE. 5 (5): e10584. Bibcode:2010PLoSO...510584C. doi: 10.1371/journal.pone.0010584 . PMC   2868044 . PMID   20485670.
  25. Abimiku, Alash'le (2012). "Update on HIV-1 diversity in Africa: a decade in review". AIDS Review. 14 (2): 83–100. PMID   22627605.