Andrew Holding | |
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Born | Andrew Nicholas Holding |
Nationality | British |
Alma mater | |
Awards | |
Scientific career | |
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Thesis | Studies on the biosynthesis of non-ribosomal peptides (2009) |
Doctoral advisor |
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Website | www |
Andrew Holding MChem (Oxon), PhD MRSC leads an academic research group at the University of York. His current research focus is the genetic drivers of breast cancer [1] and has previously published research on antibiotic biosynthesis and DNA replication. [5] Previously Holding was a Fellow of Downing College, Cambridge, [7] a Turing Fellow at The Alan Turing Institute [8] and led the experimental team in the Markowetz lab at the Cancer Research UK Cambridge Institute (a department at the University of Cambridge). [9]
Holding was educated at Whitgift School, Croydon and went on to graduate from University of Oxford with a Masters in Chemistry (MChem). In 2005 he moved to Cambridge to study at the University of Cambridge's Department of Chemistry. [9] The work he undertook towards his PhD focused on the biosynthesis of antibiotics used in the treatment of MRSA and involved both organic chemistry and microbiology. [6] [9] After completing his PhD in 2009 [6] he moved to the MRC Laboratory of Molecular Biology as a Career Development Fellow, [3] where his research focused on the structural analysis of protein complexes using mass spectrometry. [5]
In 2013 he moved to Cancer Research UK's Cambridge Institute to direct the experimental research programme of Florian Markowetz's computational research group. [10] Concurrently he was a Fellow of Downing College, Cambridge and an Associate Governor of The Vine Inter-Church Primary School. [11]
In 2019, Holding moved to the University of York [12] where he currently leads a research team focusing on the effects of steroids on cancer. [13] Specifically, Holding's team investigates how glucocorticoids drive different responses in different tissues and how this leads to an increases risk of metastasis in breast cancer patients.
Holding has worked with many organisation to promote his interests in science including The Guardian [14] and the BBC, also covering feminism and religion. [2] His 2013 show 'What If... We Were All Cyborgs?' [15] for BBC World Service was selected by Radio 4 as one their "Pick of the Week". [16] In 2019, Holding worked with the BBC World Service to use his skills as a scientist to recreate Ernest Beaux and Bourjois’s fragrance Soir de Paris from his grandfather's notebook. [17]
In 2012 Holding was awarded a British Science Association Media Fellowship to work at BBC Horizon. [18]
Holding was selected as one of 175 faces of Chemistry by the Royal Society of Chemistry [19] for a combination of his research in "fields of science crucial for improving human wellbeing" and his investment of "huge amounts of time and energy in establishing science communication, engagement, and outreach initiatives for scientists and laypeople alike". [2]
In 2015 he received a national "Rising Star" award from Cancer Research UK in recognition of "his outstanding work on raising awareness about research". [1]
Holding is married and has two daughters. [2]
Kevin Warwick is an English engineer and Deputy Vice-Chancellor (Research) at Coventry University. He is known for his studies on direct interfaces between computer systems and the human nervous system, and has also done research concerning robotics.
Venkatraman Ramakrishnan is a British-American structural biologist. He shared the 2009 Nobel Prize in Chemistry with Thomas A. Steitz and Ada Yonath for research on the structure and function of ribosomes.
Christopher Abell was a British biological chemist who was a professor of biological chemistry at the Yusuf Hamied Department of Chemistry and Todd-Hamied Fellow of Christ's College, Cambridge. On his 2016 election to the Royal Society, Abell's research was described as having "changed the face of drug discovery."
The L'Oréal-UNESCO For Women in Science Awards, created in 1998, aim to improve the position of women in science by recognizing outstanding women researchers who have contributed to scientific progress. The awards are a result of a partnership between the French company L'Oréal and the United Nations Educational, Scientific and Cultural Organization (UNESCO) and carry a grant of $100,000 USD for each laureate. This award is also known as the L'Oréal-UNESCO Women in Science Awards.
Richard Henderson is a British molecular biologist and biophysicist and pioneer in the field of electron microscopy of biological molecules. Henderson shared the Nobel Prize in Chemistry in 2017 with Jacques Dubochet and Joachim Frank. "Thanks to his work, we can look at individual atoms of living nature, thanks to cryo-electron microscopes we can see details without destroying samples, and for this he won the Nobel Prize in Chemistry."
Atta-ur-Rahman, h-index 75, with 36,000 citations is a Pakistani organic chemist and is currently serving as Professor Emeritus at the International Center for Chemical and Biological Sciences at the University of Karachi and as Chairman of PM Task Force on Science and Technology. He has twice served as the President of Pakistan Academy of Sciences. He was the Federal Minister of Science and Technology (2000-2002), Federal Minister of Education (2002) and Chairman Higher Education Commission with status of Federal Minister (2002-2008) He is also the President of the Network of Academies of Sciences in Countries of the Organisation of Islamic Countries (NASIC). After returning to Pakistan from Cambridge after completing his tenure as Fellow of Kings College, Cambridge University, he contributed to the development of the International Center for Chemical and Biological Sciences at the University of Karachi, and transforming the landscape of higher education, science and technology of Pakistan. He is Fellow of Royal Society (London), Life Fellow of Kings College, Cambridge University, UK.,, Academician Chinese Academy of Sciences and Professor Emeritus at University of Karachi
Sir Alan Rushton Battersby was an English organic chemist best known for his work to define the chemical intermediates in the biosynthetic pathway to vitamin B12 and the reaction mechanisms of the enzymes involved. His research group was also notable for its synthesis of radiolabelled precursors to study alkaloid biosynthesis and the stereochemistry of enzymic reactions. He won numerous awards including the Royal Medal in 1984 and the Copley Medal in 2000. He was knighted in the 1992 New Year Honours. Battersby died in February 2018 at the age of 92.
Sir James Baddiley FRS FRSE was a British biochemist.
Andrew Bruce Holmes is an Australian and British senior research chemist and professor at the Bio21 Institute, Melbourne, Australia, and the past President of the Australian Academy of Science. His research interests lie in the synthesis of biologically-active natural products and optoelectronic polymers.
Nigel Shaun Scrutton is a British biochemist and biotechnology innovator known for his work on enzyme catalysis, biophysics and synthetic biology. He is Director of the UK Future Biomanufacturing Research Hub, Director of the Fine and Speciality Chemicals Synthetic Biology Research Centre (SYNBIOCHEM), and Co-founder, Director and Chief Scientific Officer of the 'fuels-from-biology' company C3 Biotechnologies Ltd. He is Professor of Enzymology and Biophysical Chemistry in the Department of Chemistry at the University of Manchester. He is former Director of the Manchester Institute of Biotechnology (MIB).
Govindasamy Mugesh is an Indian inorganic and physical chemist, a professor and the head of the Mugesh Laboratory attached to the department of Inorganic and Physical Chemistry at the Indian Institute of Science. He is known for his studies on the mechanism of thyroid hormone action and is an elected fellow of the Indian Academy of Sciences, Indian National Science Academy, Royal Society of Chemistry and the National Academy of Sciences, India. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2012, for his contributions to chemical sciences. In 2019, he was awarded the Infosys Prize in Physical Sciences for his seminal work in the chemical synthesis of small molecules and nanomaterials for biomedical applications.
Alison Gail Smith, Lady Hopper is Professor of Plant Biochemistry in the Department of Plant Sciences at the University of Cambridge, UK. Her research investigates the metabolism of plants, algae and bacteria, in particular vitamin and cofactor biosynthesis.
Douglas A. Mitchell is a Professor of Chemistry at the University of Illinois at Urbana-Champaign. He holds an affiliate appointment in the Department of Microbiology and is a faculty member of the Carl R. Woese Institute for Genomic Biology. His research focuses on the chemical biology of natural products. He is known mainly for his work on the biosynthetic enzymology of ribosomally synthesized and post-translationally modified peptides (RiPPs) and genome-guided natural product discovery.
Dulal Panda is an Indian cell biologist and the chair professor at the department of biosciences and bioengineering of the Indian Institute of Technology, Bombay. Presently, he is the Director of NIPER, SAS Nagar (Mohali). Known for his studies on microtubule dynamics and FtsZ assembly dynamics, Panda is an elected fellow of the Indian Academy of Sciences and the National Academy of Sciences, India. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 2005.
John S. Fossey was a British chemist. He was a professor of synthetic chemistry at the University of Birmingham in the United Kingdom, and a visiting professor at Henan Normal University and guest professor at East China University of Science and Technology, both in China. His research was in molecular recognition and catalysis, and he was a user of boronic acid derivatives. He was a former industry fellow of the Royal Society.
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Rosalind Jane Allen is a soft matter physicist and Professor of Theoretical Microbial Ecology at the Biological Physics at the Friedrich-Schiller University of Jena, Germany, and (part-time) Professor of Biological Physics at the University of Edinburgh, Scotland She is a member of the centre for synthetic biology and systems biology where her research investigates the organisation of microbe populations.
Alice Elizabeth Motion is a British chemist, science communicator, and associate professor at the School of Chemistry, University of Sydney. She is the founder of the Breaking Good project which encourages high school and undergraduate students to take part in research that can benefit human health. In 2018, the Breaking Good project was a finalist on the Google.org Impact Challenge.
Paul J. Hergenrother is an American chemist and the Kenneth L. Rinehart Jr. Endowed Chair in Natural Products chemistry at the University of Illinois Urbana-Champaign. His research focuses on the development of organic small molecules with novel biological properties such as enzyme inhibitors and activators, chemotherapeutics, and antibacterial agents. In 2008 Hergenrother was awarded the Eli Lilly Award in Biological Chemistry.