Angela N. Brooks | |
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 Angela Brooks speaks at the Cancer Genome Atlas 4th Annual Scientific Symposium in 2015 | |
| Alma mater | University of California, Berkeley University of California, San Diego |
| Scientific career | |
| Institutions | University of California, Santa Cruz Dana–Farber Cancer Institute |
| Website | Brooks Lab |
Angela Brooks is an Assistant Professor of Biomolecular Engineering at University of California, Santa Cruz. She is a member of the Genomics Institute.
After watching Gattaca in 1997, Brooks was inspired to study genetics. [1] She studied biology at the University of California, San Diego, where she specialised in bioinformatics. She became interested in alternative splicing, and decided to focus on this for her doctoral studies. She moved to University of California, Berkeley for her graduate program, working with Steven E. Brenner. During her doctorate, she worked on Modencode, a project which looked to create an encyclopedia of the elements in the Drosophila melanogaster genomes. She created JuncBASE (junction-based analysis of splicing events), a program which analysed high-throughput sequencing data generated. [2] [3] Brooks was a postdoctoral fellow at the Dana–Farber Cancer Institute, where she worked with Matthew Meyerson. [2] Here she studied the cancerous effects of mutation in U2 small nuclear RNA auxiliary factor 1 (U2AF1) and SF3B1. [2] U2AF1 is frequently mutated in adenocarcinoma of the lung and myeloid leukemia, and SF3B1 in lymphoid leukemia. [2]
Brooks set up an alternative splicing lab at University of California, Santa Cruz in 2015. [2] She uses nanopore sequencing for full length RNA sequencing. In 2016 she was awarded a grant from the Santa Cruz Cancer Benefit Group (SCCBG) to examine genetic changes in lung cancer that lead to altered gene processing. [4] She co-lead the PanCancer Analysis of Whole Genomes (PCAWG) RNA working group [5] and is the corresponding author on the PCAWG RNA paper. [6] She also presented her PCAWG work at the AACR Annual Meeting in 2017 as part of a Major Symposia. [7]
On March 2, 2020, she was appointed the Diversity Director for the UCSC Genomics Institute. [5] In 2020 she received two grants to build diversity at the UCSC Genomics Institute including the UC Santa Cruz Training Program In Genomic Sciences [8] and UCSC Research Mentoring Internship Program: An Initiative to Increase Diversity and Inclusion in Genomics Research. [9]
Her awards and honours include;
The University of California, Santa Cruz is a public land-grant research university in Santa Cruz, California. It is one of the ten campuses in the University of California system. Located on Monterey Bay, on the edge of the coastal community of Santa Cruz, the campus lies on 2,001 acres (810 ha) of rolling, forested hills overlooking the Pacific Ocean. As of Fall 2022, its ten residential colleges enroll some 17,500 undergraduate and 2,000 graduate students.
The Baskin School of Engineering, known simply as Baskin Engineering, is the school of engineering at the University of California, Santa Cruz. It consists of six departments: Applied Mathematics, Biomolecular Engineering, Computational Media, Computer Science and Engineering, Electrical and Computer Engineering, and Statistics.
History of Consciousness is the name of a department in the Humanities Division of the University of California, Santa Cruz with a 50+ year history of interdisciplinary research and student training in "established and emergent disciplines and fields" in the humanities, arts, sciences, and social sciences based on a diverse array of theoretical approaches. The program has a history of well-known affiliated faculty and of well-known program graduates.
The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying, mapping and sequencing all of the genes of the human genome from both a physical and a functional standpoint. It started in 1990 and was completed in 2003. It remains the world's largest collaborative biological project. Planning for the project started after it was adopted in 1984 by the US government, and it officially launched in 1990. It was declared complete on April 14, 2003, and included about 92% of the genome. Level "complete genome" was achieved in May 2021, with a remaining only 0.3% bases covered by potential issues. The final gapless assembly was finished in January 2022.
The UCSC Silicon Valley Initiatives are a series of educational and research activities which together increase the presence of the University of California in Silicon Valley. To that end, UC Santa Cruz has set up a 90,000 square-foot satellite campus called the University of Santa Cruz Silicon Valley Campus (SVC), currently located on Bowers street in Santa Clara, California, where it has been since April 2016 The Initiatives, still in the early stages of their development, have had ambitious hopes attached to them by UCSC, among them the possibility of a home for the University's long-planned graduate school of management and the Bio|Info|Nano R&D Institute. It currently houses professional the SVLink incubator-accelerator program, programs and a distance education site for the UCSC Baskin School of Engineering, the UCSC Silicon Valley Extension, the Office of Industry Alliances and Technology Commercialization leadership, and the University of California's online learning program, UC Scout.
David Haussler is an American bioinformatician known for his work leading the team that assembled the first human genome sequence in the race to complete the Human Genome Project and subsequently for comparative genome analysis that deepens understanding the molecular function and evolution of the genome.
Nader Pourmand is a Professor of Biomolecular Engineering leading the Biosensors and Bioelectrical Technology Group at the Baskin School of Engineering at the University of California Santa Cruz, Baskin School of Engineering.
The UCSC Genome Browser is an online and downloadable genome browser hosted by the University of California, Santa Cruz (UCSC). It is an interactive website offering access to genome sequence data from a variety of vertebrate and invertebrate species and major model organisms, integrated with a large collection of aligned annotations. The Browser is a graphical viewer optimized to support fast interactive performance and is an open-source, web-based tool suite built on top of a MySQL database for rapid visualization, examination, and querying of the data at many levels. The Genome Browser Database, browsing tools, downloadable data files, and documentation can all be found on the UCSC Genome Bioinformatics website.
Lise Getoor is a professor in the computer science department, at the University of California, Santa Cruz, and an adjunct professor in the Computer Science Department at the University of Maryland, College Park. Her primary research interests are in machine learning and reasoning with uncertainty, applied to graphs and structured data. She also works in data integration, social network analysis and visual analytics. She has edited a book on Statistical relational learning that is a main reference in this domain. She has published many highly cited papers in academic journals and conference proceedings. She has also served as action editor for the Machine Learning Journal, JAIR associate editor, and TKDD associate editor.
Melissa Suzanne Cline is an American biologist. She is an Associate Research Scientist at the UC Santa Cruz Genomics Institute Between June 2001 and December 2004 she was a staff scientist at Affymetrix, Inc. in Emeryville, California where she was involved in developing ANOSVA, a "statistical method to identify alternative spicing from expression data," during which she "analyzed the effects of alternative splicing on protein transmembrane and signal peptide regions". Subsequently, she moved to UC Santa Cruz, where she wrote on genome browsing. According to the Thomson Reuters report, she was one of the most highly cited scientists in the world in 2012/13.
J. William Harbour is an American ophthalmologist, ocular oncologist and cancer researcher. He is Chair of the Department of Ophthalmology at the University of Texas Southwestern Medical Center in Dallas. He previously served as the vice chair and director of ocular oncology at the Bascom Palmer Eye Institute and associate director for basic science at the Sylvester Comprehensive Cancer Center of the University of Miami's Miller School of Medicine.
Patricia Zavella is an anthropologist and professor at the University of California, Santa Cruz in the Latin American and Latino Studies department. She has spent a career advancing Latina and Chicana feminism through her scholarship, teaching, and activism. She was president of the Association of Latina and Latino Anthropologists and has served on the executive board of the American Anthropological Association. In 2016, Zavella received the American Anthropological Association's award from the Committee on Gender Equity in Anthropology to recognize her career studying gender discrimination. The awards committee said Zavella’s career accomplishments advancing the status of women, and especially Latina and Chicana women have been exceptional. She has made critical contributions to understanding how gender, race, nation, and class intersect in specific contexts through her scholarship, teaching, advocacy, and mentorship. Zavella’s research focuses on migration, gender and health in Latina/o communities, Latino families in transition, feminist studies, and ethnographic research methods. She has worked on many collaborative projects, including an ongoing partnership with Xóchitl Castañeda where she wrote four articles some were in English and others in Spanish. The Society for the Anthropology of North America awarded Zavella the Distinguished Career Achievement in the Critical Study of North America Award in the year 2010. She has published many books including, most recently, "I'm Neither Here Nor There, Mexicans"Quotidian Struggles with Migration and Poverty, which focuses on working class Mexican Americans struggle for agency and identity in Santa Cruz County.
Gina Dent is an associate professor of Feminist Studies at UC Santa Cruz. She is associate dean of diversity, equity, and inclusion for the Humanities Division at UC Santa Cruz. She co authored the 2022 book Abolition. Feminism. Now. with her partner, Angela Davis; Erica Meiners; and Beth Richie.
Erika S. Zavaleta is an American professor of ecology and evolutionary biology at the University of California, Santa Cruz. Zavaleta is recognized for her research focusing on topics including plant community ecology, conservation practices for terrestrial ecosystems, and impacts of community dynamics on ecosystem functions.
Benjamin Joseph Blencowe is a British and Canadian molecular biologist, currently appointed as Professor and Banbury Chair in Medical Research at the University of Toronto. He also serves as Director of the University of Toronto’s Donnelly Sequencing Centre. He teaches in the Department of Molecular Genetics and his lab is part of the Donnelly Centre for Cellular and Biomolecular Research.
Kelly A Frazer is a Professor of Pediatrics in the Medical School at the University of California, San Diego, Chief of the Division of Genome Information Sciences and Director of the Institute for Genomic Medicine.
The UC Santa Cruz Genomics Institute is a public research institution based in the Jack Baskin School of Engineering at the University of California, Santa Cruz. The Genomics Institute's scientists and engineers work on a variety of projects related to genome sequencing, computational biology, large data analytics, and data sharing. The institute also maintains a number of software tools used by researchers worldwide, including the UCSC Genome Browser, Dockstore, and the Xena Browser.
Jean H. Langenheim was an American plant ecologist and ethnobotanist, highly respected as an eminent scholar and a pioneer for women in the field. She has done field research in arctic, tropical, and alpine environments across five continents, with interdisciplinary research that spans across the fields of chemistry, geology, and botany. Her early research helped determine the plant origins of amber and led to her career-long work investigating the chemical ecology of resin-producing trees, including the role of plant resins for plant defense and the evolution of several resin-producing trees in the tropics. She wrote what is regarded as the authoritative reference on the topic: Plant Resins: Chemistry, Evolution, Ecology, and Ethnobotany, published in 2003.
Raymond L. Rodriguez is an American professor of biology, specializing in molecular biology, genomics and biotechnology. His current research interests include diet-genome interactions, plant-made pharmaceuticals and the food/brain axis. Rodriguez is also an inventor, and entrepreneur. His research at the University of California, San Francisco in the 1970s helped lay the foundation for the biotechnology industry. He also holds several issued US patents. He is involved in programs that promote diversity, equity and inclusion for women and underrepresented minorities in science, technology, engineering, and mathematics (STEM) disciplines.
Karen Elizabeth Hayden Miga is an American geneticist who co-leads the Telomere-to-Telomore (T2T) consortium that released fully complete assembly of the human genome in March 2022. She is an assistant professor of biomolecular engineering at the University of California, Santa Cruz and Associate Director of Human Pangenomics at the UC Santa Cruz Genomics Institute. She was named as "One to Watch" in the 2020 Nature's 10 and one of Time 100’s most influential people of 2022.
| Authority control databases: Academics |
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