Steven E. Brenner

Steven Brenner
Steven E. Brenner speaking at the ISMB conference in 2015.
Born	Steven Elliot Brenner
Alma mater	Harvard University (BS) University of Cambridge (PhD)
Known for	Structural Classification of Proteins
Awards	Overton Prize (2010) [1]
Scientific career
Institutions	University of California, Berkeley Laboratory of Molecular Biology, Cambridge
Thesis	Molecular propinquity: evolutionary and structural relationships of proteins  (1996)
Doctoral advisor	Cyrus Chothia
Website	compbio.berkeley.edu

Steven Elliot Brenner is a professor at the Department of Plant and Microbial Biology at the University of California Berkeley, adjunct professor at the Department of Bioengineering and Therapeutic Sciences at the University of California, and San Francisco Faculty scientist, Physical Biosciences at the Lawrence Berkeley National Laboratory. ^{[2] [3] [4]}

Education

Brenner gained his Bachelor of Arts in 1992 from Harvard University and Doctor of Philosophy in 1997 from the University of Cambridge for research supervised by Cyrus Chothia. ^{[5] [6]} He was one of the creators of the Structural Classification of Proteins (SCOP) database ^[7] while working at the Laboratory of Molecular Biology (LMB) in Cambridge, UK.

Career and research

As of 2017 ^[update] research in Brenner's laboratory investigates:

• Individual genome interpretation ^[2]
• The regulation of gene expression by alternative splicing and nonsense-mediated decay of messenger RNA ^[2]
• Protein function prediction using Bayesian phylogenomics ^[2]

Awards and honors

In 2010 he was awarded the Overton Prize from the International Society for Computational Biology. ^{[1] [8]}

References

1. McKay, B. M.; Sansom, C. (2010). "2010 ISCB Overton Prize Awarded to Steven E. Brenner". PLOS Computational Biology . 6 (6) e1000831. Bibcode:2010PLSCB...6E0831M. doi: 10.1371/journal.pcbi.1000831 . PMC   2891695 . PMID   20585610.
2. Brenner, Steven (2017). "Brenner Laboratory: Computational Genomics Research Group". compbio.berkeley.edu.
3. Brenner, Steven E. (2013). "Be prepared for the big genome leak: It is only a matter of time until idealism sees the release of confidential genetic data on study participants". Nature. 498 (7453): 139. doi: 10.1038/498139a . PMID   23765454.
4. Stajich, J. E.; Block, D.; Boulez, K.; Brenner, S.; Chervitz, S.; Dagdigian, C.; Fuellen, G.; Gilbert, J.; Korf, I.; Lapp, H.; Lehväslaiho, H.; Matsalla, C.; Mungall, C. J.; Osborne, B. I.; Pocock, M. R.; Schattner, P.; Senger, M.; Stein, L. D.; Stupka, E.; Wilkinson, M. D.; Birney, E. (2002). "The BioPerl Toolkit: Perl Modules for the Life Sciences". Genome Research. 12 (10): 1611–1618. doi:10.1101/gr.361602. PMC   187536 . PMID   12368254.
5. Brenner, Steven Elliot (1996). Molecular propinquity: evolutionary and structural relationships of proteins. lib.cam.ac.uk (PhD thesis). University of Cambridge. OCLC   879392272. EThOS   uk.bl.ethos.596888.
6. "About Steven E. Brenner". compbio.berkeley.edu.
7. Murzin, A. G.; Brenner, S.; Hubbard, T.; Chothia, C. (1995). "SCOP: A structural classification of proteins database for the investigation of sequences and structures" (PDF). Journal of Molecular Biology . 247 (4): 536–540. doi:10.1016/S0022-2836(05)80134-2. PMID   7723011. Archived from the original (PDF) on 2012-04-26.
8. "Overton Prize winners".