Lawrence Hunter

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Larry Hunter
Larry hunter computer scientist.jpg
Larry Hunter in 2002
Born
Lawrence E. Hunter

(1961-01-18) January 18, 1961 (age 62)
Alma mater Yale University (PhD)
Known for Intelligent Systems for Molecular Biology (ISMB)
International Society for Computational Biology (ISCB)
Awards ISCB Fellow (2010)
Scientific career
Fields Computational Biology
Artificial Intelligence
Bioinformatics [1]
Institutions University of Colorado School of Medicine
George Mason University
Thesis Knowledge acquisition planning: Gaining expertise through experience  (1989)
Doctoral advisor Roger Schank [2]
Website compbio.ucdenver.edu/Hunter

Lawrence E. Hunter is a Professor and Director of the Center for Computational Pharmacology and of the Computational Bioscience Program at the University of Colorado School of Medicine and Professor of Computer Science at the University of Colorado Boulder. [3] He is an internationally known scholar, [1] [4] focused on computational biology, knowledge-driven extraction of information from the primary biomedical literature, [5] the semantic integration of knowledge resources in molecular biology, and the use of knowledge in the analysis of high-throughput data, as well as for his foundational work in computational biology, which led to the genesis of the major professional organization in the field and two international conferences. [6]

Contents

Education

Hunter completed his PhD at Yale University in 1989 with a thesis on Knowledge Acquisition Planning: Gaining Expertise Through Experience, on diagnosis of lung cancer from histological images using Case-based reasoning, [7] under the guidance of Roger Schank. [2]

Career and research

Faced with a choice between careers in the main applications of artificial intelligence---game programming and defense work—Hunter chose an emerging new discipline, bioinformatics. From 1989 to 2000, Hunter worked as a computer scientist and section chief for National Institutes of Health sections devoted to statistical and bioinformatic research. He was an adjunct faculty member at George Mason University from 1991 through 2000[ citation needed ] and an associate professor in the University of Colorado Denver School of Medicine from 2000 to 2008. He was promoted to professor in 2008. [8]

ISCB

In 1997, Hunter founded what has become the largest professional organization in computational biology and bioinformatics, the International Society for Computational Biology (ISCB). [9]

Conferences

Hunter was also a founder of three successful international conferences in bioinformatics, the International Conference on Intelligent Systems for Molecular Biology (ISMB) and the Pacific Symposium on Biocomputing (PSB) [10] and the Rocky Mountain Bioinformatics Conference. [11] He is also a co-organizer of the biological visualization conference Vizbi. [12] Hunter cofounded and was a member of the Board of Directors of the Molecular Mining Corporation from 1997 to 2003.

Awards, honors and influence

Hunter is a Fellow of the American College of Medical Informatics [ citation needed ][ when? ] and the winner of the Association for the Advancement of Artificial Intelligence (AAAI) 2003 Engelmore Prize for Innovative Applications of Artificial Intelligence.[ citation needed ]

Hunter is credited with being one of the founders of the field of bioinformatics.[ citation needed ] Throughout his career Hunter has researched and directed research groups investigating the development and application of advanced computational techniques for biomedicine to high-throughput assays, particularly the application of statistical and knowledge-based techniques, in particular bio-ontologies, [13] to the analysis of high-throughput data and of biomedical texts. He has proposed neurobiologically and evolutionarily informed computational models of cognition, and ethical issues related to computational bioscience. He has argued for expansion data science activities in biomedicine to include knowledge-based methods. [14]

He became an ISCB Fellow in 2010. Other awards and honors include Regent's Award for Scholarship and Technical Achievement 1994[ citation needed ] Meritorious Service Award, National Library of Medicine, 1991, 1992, 1993, 1994, 1995, 1996, 1997, 1998[ citation needed ] Excellence in Research Award, University of Colorado School of Medicine Department of Pharmacology, 2007[ citation needed ] Excellence in Teaching Award, University of Colorado School of Medicine Department of Preventive Medicine and Biometrics, 2004.[ citation needed ]

Publications

Selected publications include:

Related Research Articles

Biomedical text mining refers to the methods and study of how text mining may be applied to texts and literature of the biomedical domain. As a field of research, biomedical text mining incorporates ideas from natural language processing, bioinformatics, medical informatics and computational linguistics. The strategies in this field have been applied to the biomedical literature available through services such as PubMed.

<span class="mw-page-title-main">Intelligent Systems for Molecular Biology</span> Annual academic conference

Intelligent Systems for Molecular Biology (ISMB) is an annual academic conference on the subjects of bioinformatics and computational biology organised by the International Society for Computational Biology (ISCB). The principal focus of the conference is on the development and application of advanced computational methods for biological problems. The conference has been held every year since 1993 and has grown to become one of the largest and most prestigious meetings in these fields, hosting over 2,000 delegates in 2004. From the first meeting, ISMB has been held in locations worldwide; since 2007, meetings have been located in Europe and North America in alternating years. Since 2004, European meetings have been held jointly with the European Conference on Computational Biology (ECCB).

<span class="mw-page-title-main">Janet Thornton</span> British bioinformatician and academic

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<span class="mw-page-title-main">International Society for Computational Biology</span> Scholarly society

The International Society for Computational Biology (ISCB) is a scholarly society for researchers in computational biology and bioinformatics. The society was founded in 1997 to provide a stable financial home for the Intelligent Systems for Molecular Biology (ISMB) conference and has grown to become a larger society working towards advancing understanding of living systems through computation and for communicating scientific advances worldwide.

<i>Bioinformatics</i> (journal) Academic journal

Bioinformatics is a biweekly peer-reviewed scientific journal covering research and software in bioinformatics and computational biology. It is the official journal of the International Society for Computational Biology (ISCB), together with PLOS Computational Biology. Authors can pay extra for open access and are allowed to self-archive after 1 year.

The ISCB Overton Prize is a computational biology prize awarded annually for outstanding accomplishment by a scientist in the early to mid stage of his or her career. Laureates have made significant contribution to the field of computational biology either through research, education, service, or a combination of the three.

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<span class="mw-page-title-main">International Society for Computational Biology Student Council</span> Student section of the International Society for Computational Biology

The International Society for Computational Biology Student Council (ISCB-SC) is a dedicated section of the International Society for Computational Biology created in 2004. It is composed by students from all levels in the fields of bioinformatics and computational biology. The organisation promotes the development of the students' community worldwide by organizing different events including symposia, workshops, webinars, internship coordination and hackathons. A special focus is made on the development of soft skills in order to develop potential in bioinformatics and computational biology students around the world.

<span class="mw-page-title-main">European Conference on Computational Biology</span>

The European Conference on Computational Biology (ECCB) is a scientific meeting on the subjects of bioinformatics and computational biology. It covers a wide spectrum of disciplines, including bioinformatics, computational biology, genomics, computational structural biology, and systems biology. ECCB is organized annually in different European cities. Since 2007, the conference has been held jointly with Intelligent Systems for Molecular Biology (ISMB) every second year. The conference also hosts the European ISCB Student Council Symposium. The proceedings of the conference are published by the journal Bioinformatics.

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<span class="mw-page-title-main">Burkhard Rost</span> German computational biology researcher

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<span class="mw-page-title-main">Alfonso Valencia</span>

Alfonso Valencia is a Spanish biologist, ICREA Professor, current director of the Life Sciences department at Barcelona Supercomputing Center. and of Spanish National Bioinformatics Institute (INB-ISCIII). From 2015-2018, he was President of the International Society for Computational Biology. His research is focused on the study of biomedical systems with computational biology and bioinformatics approaches.

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The ISCB Innovator Award is a computational biology prize awarded annually to leading scientists who are within two decades post-degree, who consistently make outstanding contributions to the field, and who continue to forge new directions. The prize was established by the International Society for Computational Biology (ISCB) in 2016 and is awarded at the Intelligent Systems for Molecular Biology (ISMB) conference. The inaugural recipient was Serafim Batzoglou.

ISCB Fellowship is an award granted to scientists that the International Society for Computational Biology (ISCB) judges to have made “outstanding contributions to the fields of computational biology and bioinformatics”. As of 2019, there are 76 Fellows of the ISCB including Michael Ashburner, Alex Bateman, Bonnie Berger, Steven E. Brenner, Janet Kelso, Daphne Koller, Michael Levitt, Sarah Teichmann and Shoshana Wodak. See List of Fellows of the International Society for Computational Biology for a comprehensive listing.

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References

  1. 1 2 Lawrence Hunter publications indexed by Google Scholar OOjs UI icon edit-ltr-progressive.svg
  2. 1 2 Hunter, Lawrence E. (1989). Knowledge acquisition planning: Gaining expertise through experience (PhD thesis). Yale University. hdl:10079/bibid/9838922. OCLC   24116492. ProQuest   303852846.
  3. "Lawrence Hunter, Ph.D." Compbio.ucdenver.edu. Retrieved April 12, 2018.
  4. Lawrence Hunter at DBLP Bibliography Server OOjs UI icon edit-ltr-progressive.svg
  5. Hunter, L.; Cohen, K. B. (2006). "Biomedical Language Processing: What's Beyond PubMed?". Molecular Cell. 21 (5): 589–594. doi:10.1016/j.molcel.2006.02.012. PMC   1702322 . PMID   16507357.
  6. "A pioneer with personality: Larry Hunter, founder of the International Society for Computational Biology". Bioinformatics World: 6. Autumn 2002.
  7. Gibson, Todd A. (2012). "The Roots of Bioinformatics in ISMB". PLOS Computational Biology. 8 (8): e1002679. Bibcode:2012PLSCB...8E2679G. doi:10.1371/journal.pcbi.1002679. PMC   3431341 . PMID   22952443.
  8. 1 2 Hunter, Lawrence (2009). The processes of life: an introduction to molecular biology. Cambridge, Massachusetts: MIT Press. ISBN   978-0-262-01305-5.
  9. "Proceedings of the 6th International Conference on Intelligent Systems for Molecular Biology. Montreal, Quebec, Canada. June 28-July 1, 1998". Proceedings. International Conference on Intelligent Systems for Molecular Biology. 6: 1–223. 1998. PMID   9867411.
  10. "Proceedings of the 4th International Conference on Intelligent Systems for Molecular Biology. ISMB-96". Proceedings. International Conference on Intelligent Systems for Molecular Biology. 4: 1–262. 1996. PMID   9005023.
  11. "Rocky 09 - Welcome!". Iscb.org. Retrieved April 12, 2018.
  12. O'Donoghue, Sean. "VIZBI - Visualizing Biological Data". Vizbi.org. Retrieved April 12, 2018.
  13. Livingston, Kevin M.; Bada, Michael; Baumgartner, William A.; Hunter, Lawrence E. (April 23, 2015). "KaBOB: ontology-based semantic integration of biomedical databases". BMC Bioinformatics. 16 (1): 126. doi:10.1186/s12859-015-0559-3. ISSN   1471-2105. PMC   4448321 . PMID   25903923.
  14. Hunter, Lawrence E. (2017). "Knowledge-based biomedical Data Science". EPJ Data Science. 1 (1–2): 19–25. doi:10.3233/DS-170001. ISSN   2193-1127. PMC   6171523 . PMID   30294517.
  15. Leake, David B.; Ram, Ashwin (1995). Goal-driven learning. Cambridge, Massachusetts: MIT Press. ISBN   978-0-262-18165-5.
Preceded by
None
President of the
International Society for Computational Biology

1997 – 2000
Succeeded by