Gustavo Stolovitzky

Last updated

Gustavo A. Stolovitzky is an Argentine-American [1] computational systems biologist. He was the CSO of Sema4 and then of GeneDx until December 2023. Between 1998 and 2021 he was a researcher and executive at IBM Research. At IBM he served in several roles including Founding Chair of the Exploratory Life Sciences Council and Director of the Translational Systems Biology and Nano-Biotechnology Program at IBM Research. From 2013 to 2018 he was Adjunct professor of Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai and from 2007 he has been an Adjunct Associate Professor of Biomedical Informatics at Columbia University. His research has been cited more than 29,000 times [2] [3]

Contents

Stolovitzky is a co-founder of the Dialogue for Reverse Engineering Assessments and Methods (DREAM). DREAM is an international collaborative effort that leverages crowdsourcing to recognize effective methods in biomedicine and consists of more than 15,000 participants. [4] [5] Stolovitzky won the IBM Fellow award for pioneering the use of crowdsourcing for research in computational biology. [6]

Career

Stolovitzky received his M.Sc. in physics from the University of Buenos Aires in 1987, and his PhD in mechanical engineering from Yale University in 1994. In 1998, Stolovitzky joined IBM Research to work in the field of computational systems biology; he has since become the director of IBM's Translational Systems Biology and Nano-Biotechnology Program. [7] [ better source needed ] He is also an adjunct professor at Columbia University [8] and a postdoctoral researcher at the Center for Studies in Physics and Biology at The Rockefeller University.[ citation needed ] In 2005, Stolovitzky and Jared Roach developed sophisticated methods for the analysis of Massively Parallel Signature Sequencing (MPSS) data. [9] In 2008, he was a visiting scholar at the Institute for Advanced Study. [10]

Solovitztky has advocated the usage of crowdsourcing as a tool for scientific research. [11]

Recognition

Stolovitzky has received the Hispanic Engineer National Achievement Awards Corporation (HENAAC)'s Pioneer Award for Great Minds in STEM [12] [ non-primary source needed ] and the World Technology Award in Biotechnology in 2013, [13] [ non-primary source needed ] and the Raíces Prize from the Argentinian government in 2017. [14] [15] Stolovitzky is also a member of the IBM Academy of Technology [ citation needed ] and has been inducted as a Fellow of the New York Academy of Sciences, [16] Fellow of the World Technology Network, [17] [ non-primary source needed ] Fellow of the American Physical Society, [18] and Fellow of the American Association for the Advancement of Science. [19]

In 2019, Stolovitzky was appointed as an IBM Fellow, the highest technical honor IBM bestows to its employees. [1] [20]

In 2021, Stolovitzky was elected as a Fellow of the International Society for Computational Biology. [21]

Family

Stolovitzky resides in the Northeastern United States with his family. [22]

History

Stolovitzky received his M.Sc. in physics (with honors) from the University of Buenos Aires, Argentina, in 1987 and his Ph.D. in mechanical engineering from Yale University in 1994. He later explained that during a visit he paid to a friend studying in Yale, he met with K.R. Sreenivasan, who "called the provost and asked if he could add me as a PhD student, even though I hadn't formally applied to Yale and all the deadlines had already passed." [6] He did his postdoctorate at the Center for Studies in Physics and Biology at The Rockefeller University, following which he joined IBM Research in 1998. [5]

Titles and awards

Among others, Gustavo has received the following awards and titles: [5] [22] [23]

Further reading

Related Research Articles

<span class="mw-page-title-main">President's Council of Advisors on Science and Technology</span> White House advisory board

The President's Council of Advisors on Science and Technology (PCAST) is a council, chartered in each administration with a broad mandate to advise the president of the United States on science and technology. The current PCAST was established by Executive Order 13226 on September 30, 2001, by George W. Bush, was re-chartered by Barack Obama's April 21, 2010, Executive Order 13539, by Donald Trump's October 22, 2019, Executive Order 13895, and by Joe Biden's February 1, 2021, Executive Order 14007.

<span class="mw-page-title-main">Temple F. Smith</span> American academic

Temple Ferris Smith is an emeritus professor in biomedical engineering who helped to develop the Smith-Waterman algorithm with Michael Waterman in 1981. The Smith-Waterman algorithm serves as the basis for multi sequence comparisons, identifying the segment with the maximum local sequence similarity, see sequence alignment. This algorithm is used for identifying similar DNA, RNA and protein segments. He was director of the BioMolecular Engineering Research Center at Boston University for twenty years and is now professor emeritus.

<span class="mw-page-title-main">Yves A. Lussier</span>

Yves A. Lussier is a physician-scientist conducting research in Precision medicine, Translational bioinformatics and Personal Genomics. As a co-founder of Purkinje, he pioneered the commercial use of controlled medical vocabulary organized as directed semantic networks in electronic medical records, as well as Pen computing for clinicians.

Pierre Baldi is a distinguished professor of computer science at University of California Irvine and the director of its Institute for Genomics and Bioinformatics.

<span class="mw-page-title-main">International Society for Computational Biology</span> Scholarly society

The International Society for Computational Biology (ISCB) is a scholarly society for researchers in computational biology and bioinformatics. The society was founded in 1997 to provide a stable financial home for the Intelligent Systems for Molecular Biology (ISMB) conference and has grown to become a larger society working towards advancing understanding of living systems through computation and for communicating scientific advances worldwide.

Mark Borodovsky is a Regents' Professor at the Join Wallace H. Coulter Department of Biomedical Engineering of Georgia Institute of Technology and Emory University and Director of the Center for Bioinformatics and Computational Genomics at Georgia Tech. He has also been a Chair of the Department of Bioinformatics at the Moscow Institute of Physics and Technology in Moscow, Russia from 2012 to 2022.

Dimitris Anastassiou is an electrical engineer and Charles Batchelor Professor of Electrical Engineering in the Columbia University School of Engineering. Anastassiou's earlier work focuses primarily on signal and information processing and reverse engineering. His more recent work involves interdisciplinary research, specifically in systems biology, with investigators at Columbia University Medical Center. Anastassiou is Fellow of the IEEE for contributions to video technology, developing high-performance digital image and video coding techniques . He is also a Fellow of the National Academy of Inventors and recipient of both the National Science Foundation Presidential Young Investigator Award and the IBM Outstanding Innovation Award.

Trey Ideker is a professor of medicine and bioengineering at UC San Diego. He is the Director of the National Resource for Network Biology, the San Diego Center for Systems Biology, and the Cancer Cell Map Initiative. He uses genome-scale measurements to construct network models of cellular processes and disease.

<span class="mw-page-title-main">Atul Butte</span> American medical researcher

Atul J. Butte is a biomedical informatics researcher and biotechnology entrepreneur. He is currently the Priscilla Chan and Mark Zuckerberg Distinguished Professor at the University of California, San Francisco. Since April 2015, Butte has serves as inaugural director of UCSF's Bakar Computational Health Sciences Institute.

<span class="mw-page-title-main">David Sankoff</span> Canadian scientist

David Sankoff is a Canadian mathematician, bioinformatician, computer scientist and linguist. He holds the Canada Research Chair in Mathematical Genomics in the Mathematics and Statistics Department at the University of Ottawa, and is cross-appointed to the Biology Department and the School of Information Technology and Engineering. He was founding editor of the scientific journal Language Variation and Change (Cambridge) and serves on the editorial boards of a number of bioinformatics, computational biology and linguistics journals. Sankoff is best known for his pioneering contributions in computational linguistics and computational genomics. He is considered to be one of the founders of bioinformatics. In particular, he had a key role in introducing dynamic programming for sequence alignment and other problems in computational biology. In Pavel Pevzner's words, "[ Michael Waterman ] and David Sankoff are responsible for transforming bioinformatics from a ‘stamp collection' of ill-defined problems into a rigorous discipline with important biological applications."

Mona Singh is a Professor of Computer Science in the Lewis-Sigler Institute for Integrative Genomics at Princeton University.

Satoru Miyano is a professor and the director of the M&D Data Science Center at Tokyo Medical and Dental University. He was awarded fellowship of the International Society for Computational Biology (ISCB) in 2013 for outstanding contributions to the fields of computational biology and bioinformatics.

Xiaole Shirley Liu (刘小乐) is computational biologist, cancer researcher, and entrepreneur. She has been a Professor in the Department of Data Sciences at the Dana-Farber Cancer Institute and Harvard T.H. Chan School of Public Health. She is now the co-founder and CEO of GV20 Therapeutics.

Barry H. Honig is an American biochemist, molecular biophysicist, and computational biophysicist, who develops theoretical methods and computer software for "analyzing the structure and function of biological macromolecules."

Eleazar Eskin is a computer scientist and geneticist, professor and Chair of the Department of Computational Medicine, and professor of computer science and human genetics at the University of California, Los Angeles. His research focuses on bioinformatics, genomics, and machine learning. A primary research focus is on developing statistical and computational techniques to probe the genetic basis of human disease.

Katherine Snowden Pollard is the Director of the Gladstone Institute of Data Science and Biotechnology and a professor at the University of California, San Francisco (UCSF). She is a Chan Zuckerberg Biohub Investigator. She was awarded Fellowship of the International Society for Computational Biology in 2020 and the American Institute for Medical and Biological Engineering in 2021 for outstanding contributions to computational biology and bioinformatics.

Zhiping Weng is the Li Weibo Professor of biomedical research and chair of the program in integrative biology and bioinformatics at the University of Massachusetts Medical School. She was awarded Fellowship of the International Society for Computational Biology (ISCB) in 2020 for outstanding contributions to computational biology and bioinformatics.

<span class="mw-page-title-main">M. Madan Babu</span> Indian-American computational biologist

M. Madan Babu is an Indian-American computational biologist and bioinformatician. He is the endowed chair in biological data science and director of the center of excellence for data-driven discovery at St. Jude Children’s Research Hospital. Previously, he served as a programme leader at the MRC Laboratory of Molecular Biology (LMB).

<span class="mw-page-title-main">Nikolay Dokholyan</span> Russian-American Biophysicist, academic and researcher

Nikolay V. Dokholyan is an American biophysicist, academic and researcher. He is a G. Thomas Passananti Professor and Vice Chair for Research at Penn State College of Medicine.

DREAM Challenges is a non-profit initiative for advancing biomedical and systems biology research via crowd-sourced competitions. Started in 2006, DREAM challenges collaborate with Sage Bionetworks to provide a platform for competitions run on the Synapse platform. Over 60 DREAM challenges have been conducted over the span of over 15 years.

References

  1. 1 2 "Gustavo Stolovitzky". IBM. 2019. Retrieved May 17, 2020.
  2. "Loop | Gustavo Stolovitzky". loop.frontiersin.org. Retrieved 2020-04-16.
  3. "G Stolovitzky - Google Scholar Citations". scholar.google.com. Retrieved 2020-04-16.
  4. "Gustavo Stolovitzky | Columbia University Department of Systems Biology". systemsbiology.columbia.edu. Retrieved 2020-04-16.
  5. 1 2 3 "Gustavo A. Stolovitzky - IBM". researcher.watson.ibm.com. 2016-07-25. Retrieved 2020-04-16.
  6. 1 2 "2019 IBM Fellow Gustavo Stolovitzky". 2019 IBM Fellow Gustavo Stolovitzky. 2019-04-11. Retrieved 2020-04-16.
  7. "Translational Systems Biology and Nanotechnology Group". IBM Research Groups. September 9, 2019. Retrieved May 17, 2020.
  8. "Gustavo Stolovitzky". Columbia University Department of Systems Biology. Retrieved May 17, 2020.
  9. Yegnasubramanian, Srinivasan (September 2, 2010). Modern Molecular Biology: Approaches for Unbiased Discovery in Cancer Research. Springer New York. p. 102. ISBN   9780387697451.
  10. "Gustavo A. Stolovitzky". Institute for Advanced Study . 9 December 2019. Retrieved May 19, 2020.
  11. Baker, Monya (August 2012). "The author file: Gustavo Stolovitzky" (PDF). Nature Methods . 9 (8): 767. doi: 10.1038/nmeth.2113 . PMID   23019684.
  12. "2013 HENAAC Award Winners". Great Minds in STEM. Retrieved May 17, 2020.
  13. "The 2013 World Technology Award Finalists". The World Technology Network. Retrieved May 17, 2020.
  14. "Premiados 2017". Argentina.gob.ar. 29 April 2019. Retrieved May 17, 2020.
  15. "Entregaron los premios RAÍCES y Luis Federico Leloir". El 1 Digital (in Spanish). November 17, 2017.
  16. "Honorary Members and Academy Fellows". The New York Academy of Sciences. Retrieved May 17, 2020.
  17. "Members". The World Technology Network. Retrieved May 17, 2020.
  18. "APS Fellow Archive". APS Physics. Retrieved May 17, 2020.
  19. "AAAS Members Elected as Fellows". American Association for the Advancement of Sciences. January 11, 2011. Retrieved May 17, 2020.
  20. "IBM Fellows". IBM. 13 April 2017. Retrieved May 17, 2020.
  21. "March 02, 2021: ISCB Congratulates and Introduces the 2021 Class of Fellows!". www.iscb.org. Retrieved 17 June 2022.
  22. 1 2 "Gustavo A. Stolovitzky". Institute for Advanced Study. 9 December 2019. Retrieved 2020-04-16.
  23. "Gustavo Stolovitzky" (PDF). Nature Methods. 9. August 2012.