Anthony G. Letai is an American cancer researcher and oncologist serving as the director of the National Cancer Institute since 2025. [1] He studies cell death in cancer, developing treatments, and identifying predictive biomarkers. [1] Letai was a professor of medicine at Harvard Medical School and a medical oncologist at the Dana–Farber Cancer Institute. [2]
Letai earned a B.A. in physics from Princeton University. He received an M.D. (1995) and Ph.D. (1993) from the University of Chicago Pritzker School of Medicine. [3] He completed his Ph.D. on the molecular basis of heritable blistering diseases before residency in internal medicine at Brigham and Women's Hospital and a clinical fellowship in hematology and oncology at Dana–Farber Cancer Institute. Letai began his studies of programmed cell death in cancer in a post-doctoral fellowship before establishing his laboratory at Dana–Farber Cancer Institute to study how apoptosis can be evaded by cancer cells. [1]
Letai and his wife, Jean, have three children. Their daughter Julie Letai represented Team USA in speed skating at the 2022 Winter Olympics and is a member of U.S. Speedskating's Short Track World Tour Team as it prepares for the 2026 Games in Milan. [1]