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Schering-Plough Corporation was an American pharmaceutical company. It was originally the U.S. subsidiary of the German company Schering AG, which was founded in 1851 by Ernst Christian Friedrich Schering. As a result of nationalization, it became an independent company. In 1971, the Schering Corporation merged with Plough, Inc. to form Schering-Plough. On November 4, 2009 Merck & Co. merged with Schering-Plough with the new company taking the name of Merck & Co.
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Aspirin is a novel organic compound that does not occur in nature, and was first successfully synthesised in 1899. In 1897, scientists at the drug and dye firm Bayer began investigating acetylated organic compounds as possible new medicines, following the success of acetanilide ten years earlier. By 1899, Bayer created acetylsalicylic acid and named the drug 'Aspirin', going on to sell it around the world. The word Aspirin was Bayer's brand name, rather than the generic name of the drug; however, Bayer's rights to the trademark were lost or sold in many countries. Aspirin's popularity grew over the first half of the twentieth century, leading to fierce competition with the proliferation of aspirin brands and products.
The Bayer AG is a German multinational pharmaceutical and biotechnology company and is one of the largest pharmaceutical companies and biomedical companies in the world. Headquartered in Leverkusen, Bayer's areas of business include: pharmaceuticals, consumer healthcare products, agricultural chemicals, seeds and biotechnology products. The company is a component of the EURO STOXX 50 stock market index.
A transdermal analgesic or pain relief patch is a medicated adhesive patch used to relieve minor to severe pain. There are many types of analgesic patches based on the main ingredients in the patches. These include patches containing counterirritants, which are used to treat mild to moderate pain, and patches containing opioids such as buprenorphine and fentanyl, used to relieve moderate to severe pain. Fentanyl is often used for opioid-tolerant patients. Nitroglycerin, also known as glyceryl trinitrate (GTN), a medication used for heart failure, high blood pressure, anal fissures, painful periods, and to treat and prevent chest pain, can also be found in patches. Beyond these are patches that contain drugs such as diclofenac and lidocaine and various other drugs. The main purpose of transdermal analgesic patches are to administer drugs in a more viable way to patients, as opposed to oral consumption or intravenous administration such as an injection.
Hydrocodone/ibuprofen (INNs), sold under the brand name Vicoprofen, is a fixed-dose combination analgesic medication used in short-term therapy to relieve severe pain. Vicoprofen combines the analgesic and antitussive properties of hydrocodone with the analgesic, anti-inflammatory, and antipyretic properties of ibuprofen. In contrast to hydrocodone/acetaminophen combination analgesics such as Vicodin, this hydrocodone/ibuprofen avoids some of the liver toxicity which may occur from acetaminophen, but still presents significant dangers in hydrocodone overdose, namely respiratory depression. Vicoprofen is supplied in a fixed dose combination tablet which contains hydrocodone bitartrate, USP 7.5 mg with ibuprofen, USP 200 mg. Additional strengths of generic Vicoprofen are now available, in combinations of 5 mg/200 mg and 10 mg/200 mg respectively.
References
- ↑ Aspirin Archived 14 July 2007 at the Wayback Machine , online reference, Complementary Medicine, University of Maryland Medical Center
- ↑ U.S. Trademark Notice-Acceptance-Renewal dated January 16, 2006 [ permanent dead link ]
- ↑ Washington, Neena et al. (21 December 2000) Physiological Pharmaceutics: Barriers to Drug Absorption. Page 49. Publisher: CRC. ISBN 0-7484-0562-3
- ↑ United States Trademark No. 240,417. [ permanent dead link ]
- ↑ Advertisement, Appleton Post Crescent, Wisconsin, 15 October 1930
- ↑ Sohn, Emily. (19 February 2007), "Chew on this: It's for your health Suppress appetite, boost memory, fight disease. Gums could do it all – thanks to the cheeks", Los Angeles Times , Section: Health; Page 1.
- ↑ Aspirin resistance, text MIM 608223, Online Mendelian Inheritance in Man
- ↑ Aspirin and Coronary Thrombosis Archived 11 July 2007 at the Wayback Machine , Aspirin Foundation
- ↑ Graedon, Joe; Graedon, Teresa. (12 August 1997) The Baltimore Sun . Take two aspirin and sing "Happy Birthday." Section: Features; Page 4E.
- ↑ Farmaci Generici. – Il Miglior Prezzo – Acido Acetilasalicilico. Archived 2 August 2007 at the Wayback Machine Obtained 16 July 2007.
- ↑ Wiegand, David. (27 April 1997) San Francisco Chronicle . "Making sense of Streisand – How seeking her mother's approval and losing her father shaped her career." Section: Sunday Review; page 4.
- ↑ Owens, Lamar (14 April 1998). "Gumtech to Produce Aspergum and Chooz for Schering-Plough HealthCare Products" (Press release). Business Wire. Archived from the original on 22 February 2015. Retrieved 15 December 2014– via The Free Library.