Joel Daniel Coen and Ethan Jesse Coen, collectively known as the Coen brothers, are an American filmmaking duo. Their films span many genres and styles, which they frequently subvert or parody. Their most acclaimed works include Blood Simple (1984), Raising Arizona (1987), Miller's Crossing (1990), Barton Fink (1991), Fargo (1996), The Big Lebowski (1998), O Brother, Where Art Thou? (2000), No Country for Old Men (2007), A Serious Man (2009), True Grit (2010) and Inside Llewyn Davis (2013). Many of their films are distinctly American, often examining the culture of the American South and American West in both modern and historical contexts.
The Big Lebowski is a 1998 crime comedy film written, produced, and directed by Joel and Ethan Coen. It stars Jeff Bridges as Jeffrey "The Dude" Lebowski, a Los Angeles slacker and avid bowler. He is assaulted as a result of mistaken identity, then learns that a millionaire, also named Jeffrey Lebowski, was the intended victim. The millionaire Lebowski's trophy wife is kidnapped, and millionaire Lebowski commissions The Dude to deliver the ransom to secure her release. The plan goes awry when the Dude's friend, Walter Sobchak, schemes to keep the ransom money for the Dude and himself. Sam Elliott, Julianne Moore, Steve Buscemi, John Turturro, Philip Seymour Hoffman, Tara Reid, David Thewlis, Peter Stormare, Jon Polito, and Ben Gazzara also appear in supporting roles.
No Country for Old Men is a 2007 American neo-Western crime thriller film written and directed by Joel and Ethan Coen, based on Cormac McCarthy's 2005 novel of the same name. Starring Tommy Lee Jones, Javier Bardem, and Josh Brolin, the film is set in the desert landscape of 1980 West Texas. The film revisits the themes of fate, conscience, and circumstance that the Coen brothers had explored in the films Blood Simple (1984), Raising Arizona (1987), and Fargo (1996). The film follows three main characters: Llewelyn Moss (Brolin), a Vietnam War veteran and welder who stumbles upon a large sum of money in the desert; Anton Chigurh (Bardem), a hitman who is sent to recover the money; and Ed Tom Bell (Jones), a sheriff investigating the crime. The film also stars Kelly Macdonald as Moss's wife Carla Jean and Woody Harrelson as a bounty hunter seeking Moss and the return of the $2 million.
Bath salts are water-soluble, pulverized minerals that are added to water to be used for bathing. It is said that these salts are used to improve cleaning, enhance the enjoyment of bathing, and serve as a vehicle for cosmetic agents. Bath salts have been developed which mimic the properties of natural mineral baths or hot springs. Some bath salts contain glycerine so the product will act as an emollient, humectant, or lubricant. Fragrances and colors are often added to bath salts; the fragrances are used to increase the users' enjoyment of the bathing experience.
Methylenedioxypyrovalerone (MDPV) is a stimulant of the cathinone class that acts as a norepinephrine–dopamine reuptake inhibitor (NDRI). It was first developed in the 1960s by a team at Boehringer Ingelheim. Its activity at the dopamine transporter is six times stronger than at the norepinephrine transporter and it is virtually inactive at the serotonin transporter. MDPV remained an obscure stimulant until around 2004 when it was reportedly sold as a designer drug. In the USA, products containing MDPV and labeled as bath salts were sold as recreational drugs in gas stations, similar to the marketing for Spice and K2 as incense, until it was banned in 2011.
Etravirine is a drug used for the treatment of HIV. Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). Unlike the currently available agents in the class, resistance to other NNRTIs does not seem to confer resistance to etravirine. Etravirine is marketed by Janssen, a subsidiary of Johnson & Johnson. In January 2008, the Food and Drug Administration approved its use for patients with established resistance to other drugs, making it the 30th anti-HIV drug approved in the United States and the first to be approved in 2008. It was also approved for use in Canada on April 1, 2008.
My Girlfriend's Boyfriend is a PG-rated 2010 American romantic comedy film written and directed by Daryn Tufts, and stars Alyssa Milano, Christopher Gorham, Michael Landes, Beau Bridges, Tom Lenk and Carol Kane.
α-Pyrrolidinopentiophenone is a synthetic stimulant of the cathinone class developed in the 1960s that has been sold as a designer drug. Colloquially, it is sometimes called flakka. α-PVP is chemically related to pyrovalerone and is the ketone analog of prolintane.
On May 26, 2012, Rudy Eugene attacked and maimed Ronald Poppo, a homeless man, on the MacArthur Causeway in Miami, Florida, US making headlines worldwide. During the 18-minute filmed encounter, Eugene accused Poppo of stealing his Bible, beat him unconscious, removed Poppo's pants (trousers), and bit off most of Poppo's face above his beard, leaving him blind in both eyes. As a result of the incident's shocking nature and subsequent worldwide media coverage, Eugene came to be dubbed the "Miami Zombie" and the "Causeway Cannibal". The attack ended when Eugene was fatally shot by an officer of the Miami Police Department.
Bath salts are a group of recreational designer drugs. The name derives from instances in which the drugs were disguised as bath salts. The white powder, granules, or crystals often resemble Epsom salts, but differ chemically. The drugs' packaging often states "not for human consumption" in an attempt to circumvent drug prohibition laws. Additionally, they may be mislabeled as plant food, powdered cleaner, and other such products.
Hansel & Gretel is a 2013 American direct-to-video dark fantasy horror film produced by The Asylum and directed by Anthony C. Ferrante, starring Dee Wallace, Brent Lydic and Stephanie Greco. The film is a modern retelling of the Brothers Grimm fairytale of the same name, taking place in Candlewood, New Jersey and follows the eponymous pair of adolescent siblings who find themselves kidnapped by a cannibalistic bakery-owning witch who devours human meat as a way to rejuvenate her youth.
Scenic Route, also known in the UK as Wrecked, is a 2013 American psychological thriller film written by Kyle Killen, directed by Kevin and Michael Goetz, and starring Josh Duhamel and Dan Fogler. The film premiered at the 2013 South by Southwest Film Festival and was released on August 23, 2013.
Beverly Lane is 2010 comedy horror written and directed by Joshua Hull. It stars Jim O'Rear, Noah East, Raymond Kester, Donald A. Becker, James Copeland, and Mark A. Nash. East plays an office worker who must defend himself against zombies, unhelpful co-workers, and annoying party entertainers.
Resolution is a 2012 American horror film directed by Justin Benson and Aaron Scott Moorhead, written by Benson, and starring Peter Cilella and Vinny Curran. Cilella plays a graphic designer and father-to-be named Michael who, after receiving a troubling email video of his drug-addicted best friend Chris, travels to a remote cabin to save him. The 2017 film The Endless shares the same creative universe as Resolution, and may be interpreted as a partial sequel.
Mimesis: Night of the Living Dead is a 2011 American horror film directed by Douglas Schulze, written by Joshua Wagner and Schulze, and starring Allen Maldonado, Lauren Mae Shafer, Taylor Piedmonte, and David G.B. Brown.
Hellgate is a 2011 American-Thai supernatural thriller directed and written by John Penney, starring William Hurt and Cary Elwes. Elwes plays the sole survivor of a car crash who, upon seeing ghosts, seeks help from a spiritual guru (Hurt).
Hail, Caesar! is a 2016 period black comedy film written, produced, edited, and directed by the brothers Joel and Ethan Coen. An American-British co-production, the film stars Josh Brolin, George Clooney, Alden Ehrenreich, Ralph Fiennes, Jonah Hill, Scarlett Johansson, Frances McDormand, Tilda Swinton, and Channing Tatum, with Michael Gambon as the narrator. It is a fictional story that follows the real-life studio fixer Eddie Mannix (Brolin), working in the Hollywood film industry in the 1950s, trying to discover what happened to a star actor during the filming of a biblical epic.
Daniel Boyd is an American filmmaker, author, and communications professor. He currently teaches at West Virginia State University, has hosted writing workshops, and received a Fulbright Fellowship in 1998.
Magnesium sulfate as a medication is used to treat and prevent low blood magnesium and seizures in women with eclampsia. It is also used in the treatment of torsades de pointes, severe asthma exacerbations, constipation, and barium poisoning. It is given by injection into a vein or muscle as well as by mouth. As epsom salts, it is also used for mineral baths.
