| Blue toe syndrome | |
|---|---|
| Specialty | Cardiology |
Blue toe syndrome occurs when small clots, often from atherothrombotic microembolism (clots formed from fatty deposits in artery walls), partially block blood flow to the toes. This can cause transient focal ischemia and occasionally minor tissue loss, but generally does not affect the entire forefoot. Blue or violaceous toes can also result from trauma, cold-induced injury, disorders causing generalized cyanosis, reduced arterial blood flow, impaired venous drainage, or blood abnormalities. [1] [2] [3] [4] The terms "blue toe syndrome," "grey toe syndrome," and "purple toe syndrome" are often used interchangeably. [5]
Diagnostic evaluation may include echocardiography, thoracic or abdominal CT or MRI, [6] [7] [8] [9] peripheral arterial imaging, blood tests for hypercoagulable states, and assessment for conditions that affect peripheral blood flow. [10]