Botswana Vaccine Institute

Last updated

Botswana Vaccine Institute
BVI
Veterinary Research Institute overview
Formed1978;46 years ago (1978)
TypeVeterinary Research Institute
Jurisdiction Government of Botswana
HeadquartersBroadhurst Industrial Park, 6385/6390 Lejara Road, Gaborone, Botswana
Veterinary Research Institute executives
Website Homepage

The Botswana Vaccine Institute (BVI) is a veterinary research institute owned by the Botswana government that carries out research on communicable diseases in domestic animals, with emphasis on viral transmitted infections. BVI manufactures vaccines against major animal diseases for use in Botswana and for sale in 16 African and Middle Eastern countries. BVI is a "leader in the research, manufacture and supply of livestock vaccines". [1]

Contents

Location

The headquarters and main offices of BVI are located in Broadhurst Industrial Park, 6385/90 Lejara Road, in the city of Gaborone, the capital of Botswana. [2]

Overview

BVI was founded in 1978. In 1979 the institution was registered as Botswana Vaccine Institute Limited, a self-funding company wholly owned by the government of Botswana. Over time, BVI forged a partnership with Merial, the French pharmaceutical conglomerate. Starting with vaccines against FMD, the institute has diversified into the research and manufacture of vaccines against anthrax, Contagious bovine pleuropneumonia, Ovine rinderpest, black quarter disease and rabies. The institute is an international reference laboratory on FMD. [1] [3] [4] [5]

Developments

In February 2024, BVI and the Uganda Ministry of Agriculture, Animal Industry and Fisheries, began collaboration to manufacture a type-specific vaccine for FMD suitable for Uganda, for control of the disease and the prevention of future outbreaks. [6]

See also

Related Research Articles

<span class="mw-page-title-main">Agricultural policy</span> Laws relating to domestic agriculture and foreign-imported agricultural products

Agricultural policy describes a set of laws relating to domestic agriculture and imports of foreign agricultural products. Governments usually implement agricultural policies with the goal of achieving a specific outcome in the domestic agricultural product markets.

<span class="mw-page-title-main">Plum Island Animal Disease Center</span> American research facility

Plum Island Animal Disease Center (PIADC) is a United States federal research facility dedicated to the study of foreign animal diseases of livestock. It is a national laboratory of the Department of Homeland Security (DHS) Directorate for Science and Technology (S&T), and operates as a partnership with the U.S. Department of Agriculture (USDA). The facility's director is Dr. Larry Barrett.

<span class="mw-page-title-main">2001 United Kingdom foot-and-mouth outbreak</span> Epidemic in 2001 in the UK

The outbreak of foot-and-mouth disease in the United Kingdom in 2001 caused a crisis in British agriculture and tourism. This epizootic saw 2,000 cases of the disease in farms across most of the British countryside. Over 6 million cows and sheep were killed in an eventually successful attempt to halt the disease. Cumbria was the worst affected area of the country, with 893 cases.

<span class="mw-page-title-main">Pasteur Institute</span> French disease research organization

The Pasteur Institute is a French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines. It is named after Louis Pasteur, who invented pasteurization and vaccines for anthrax and rabies. The institute was founded on 4 June 1887 and inaugurated on 14 November 1888.

<span class="mw-page-title-main">Instituto Butantan</span>

The Instituto Butantan is a Brazilian biologic research center located in Butantã, in the western part of the city of São Paulo, Brazil. Instituto Butantan is a public institution affiliated with the São Paulo State Secretariat of Health and considered one of the major scientific centers in the world. Butantan is the largest immunobiologicals and biopharmaceuticals producer in Latin America. It is world-renowned for its collection of venomous snakes, as well as those of venomous lizards, spiders, insects and scorpions. By extracting the reptiles' and insects' venoms, the Institute develops antivenoms and medicines against many diseases, which include tuberculosis, rabies, tetanus and diphtheria.

<span class="mw-page-title-main">Wistar Institute</span> American biomedical research institute

The Wistar Institute is an independent, nonprofit research institution in biomedical science with special focuses in oncology, immunology, infectious disease and vaccine research. Located on Spruce Street in Philadelphia’s University City neighborhood, Wistar was founded in 1892 as a nonprofit institution to focus on biomedical research and training.

<span class="mw-page-title-main">Foundation for Biomedical Research</span> American animal welfare organization

The Foundation for Biomedical Research (FBR) is an American nonprofit organization, 501(c)(3), located in Washington, DC. Established in 1981, the organization is dedicated to informing the news media, teachers, and other groups about the need for lab animals in medical and scientific research. The organization, together with its partner, the National Association for Biomedical Research (NABR), argues that promoting animal research leads to improved health for both humans and animals.

<span class="mw-page-title-main">Trinidad Regional Virus Laboratory</span>

The Trinidad Regional Virus Laboratory (T.R.V.L.) was established in Port of Spain, in 1953 by the Rockefeller Foundation in co-operation with the Government of Trinidad and Tobago. It was originally housed in an old wooden army barracks near the docks in Port of Spain. A large wired-in "animal house" was built out back to house the many wild animals brought in for study.

<span class="mw-page-title-main">Biological Institute (São Paulo)</span>

Biological Institute is an applied research center organised in 1924 in São Paulo, Brazil. It is a governmental organisation concerned with the prevention of zoonoses and foodborne animal pathogens such as rabies and tuberculosis, sanitary advertisement campaigns, alternatives to the chemical control of diseases such as organic farming and biological control.

<span class="mw-page-title-main">Rabies vaccine</span> Vaccines to prevent rabies in humans and animals

The rabies vaccine is a vaccine used to prevent rabies. There are several rabies vaccines available that are both safe and effective. Vaccinations must be administered prior to rabies virus exposure or within the latent period after exposure to prevent the disease. Transmission of rabies virus to humans typically occurs through a bite or scratch from an infectious animal, but exposure can occur through indirect contact with the saliva from an infectious individual.

<span class="mw-page-title-main">Rabies</span> Deadly viral disease, transmitted through animals

Rabies is a viral disease that causes encephalitis in humans and other mammals. It was historically referred to as hydrophobia due to the symptom of panic when presented with liquids to drink. Early symptoms can include fever and abnormal sensations at the site of exposure. These symptoms are followed by one or more of the following symptoms: nausea, vomiting, violent movements, uncontrolled excitement, fear of water, an inability to move parts of the body, confusion, and loss of consciousness. Once symptoms appear, the result is virtually always death, regardless of treatment. The time period between contracting the disease and the start of symptoms is usually one to three months but can vary from less than one week to more than one year. The time depends on the distance the virus must travel along peripheral nerves to reach the central nervous system.

<span class="mw-page-title-main">Rabies in animals</span> Deadly zoonotic disease

In animals, rabies is a viral zoonotic neuroinvasive disease which causes inflammation in the brain and is usually fatal. Rabies, caused by the rabies virus, primarily infects mammals. In the laboratory it has been found that birds can be infected, as well as cell cultures from birds, reptiles and insects. The brains of animals with rabies deteriorate. As a result, they tend to behave bizarrely and often aggressively, increasing the chances that they will bite another animal or a person and transmit the disease.

<span class="mw-page-title-main">Foot-and-mouth disease</span> Infectious disease affecting cattle

Foot-and-mouth disease (FMD) or hoof-and-mouth disease (HMD) is an infectious and sometimes fatal viral disease that affects cloven-hoofed animals, including domestic and wild bovids. The virus causes a high fever lasting two to six days, followed by blisters inside the mouth and near the hoof that may rupture and cause lameness.

<span class="mw-page-title-main">Indian Immunologicals Limited</span> Subsidiary of National Dairy Development Board

Indian Immunologicals Limited (IIL) is a subsidiary of the National Dairy Development Board. It is based in Hyderabad, Telangana, India. IIL is registered in India as a Public Limited Company under the Companies Act, 1956, It was established in 1982 by the National Dairy Development Board.

Lt.-Col. Noel St George Hyslop, TD was a British physician, veterinary surgeon and public health officer.

Makerere University Walter Reed Project (MUWRP) was established in 2002 for the primary purpose of HIV vaccine development and building of vaccine testing capability in Uganda. It is one of the 5 international research sites established by the Department of Defense (DoD) United States HIV Research Program (MHRP), a program centered at the Walter Reed Army Institute of Research (WRAIR) in Silver Spring, Maryland. MUWRP's main facility is centrally located in Kampala, near the Makerere University College of Health Sciences where the MUWRP laboratory is located. The main facility includes the clinic, administrative, and data offices.

<span class="mw-page-title-main">Rabies in Haiti</span> Viral disease in Haiti

Rabies is a viral disease that exists in Haiti and throughout the world. It often causes fatal inflammation of the brain in humans and other mammals, such as dogs and mongooses in Haiti. The term "rabies" is derived from a Latin word that means "to rage"; rabid animals sometimes appear to be angry. Early symptoms can include fever and tingling at the site of exposure, followed by one or more of the following symptoms: violent movements, uncontrolled excitement, fear of water, an inability to move parts of the body, confusion, and loss of consciousness. Once symptoms appear, death is nearly always the outcome. The time period between contracting the disease and showing symptoms is usually one to three months; however, this time period can vary from less than a week to more than a year. The time between contraction and the onset of symptoms is dependent on the distance the virus must travel to reach the central nervous system.

<span class="mw-page-title-main">Animal vaccination</span> Process

Animal vaccination is the immunisation of a domestic, livestock or wild animal. The practice is connected to veterinary medicine. The first animal vaccine invented was for chicken cholera in 1879 by Louis Pasteur. The production of such vaccines encounter issues in relation to the economic difficulties of individuals, the government and companies. Regulation of animal vaccinations is less compared to the regulations of human vaccinations. Vaccines are categorised into conventional and next generation vaccines. Animal vaccines have been found to be the most cost effective and sustainable methods of controlling infectious veterinary diseases. In 2017, the veterinary vaccine industry was valued at US$7 billion and it is predicted to reach US$9 billion in 2024.

Sir Percy John Luxton Kelland, known as Sir John Kelland, was the Chief Veterinary Officer in the Diseases of Animals Branch at the Ministry of Agriculture and Fisheries between 1932 and 1938.

The National Veterinary Research Institute (NVRI) is a research institute in Nigeria that was established in 1924 and has the mandate to conduct research into how to ably identify, treat and control animal diseases as well as the development of vaccines for such and training and the provision of support services to livestock and poultry farmers. The institute is under the supervision of Federal Ministry of Agriculture and Rural Development. The chief executive is Maryam Muhammad, a veterinary doctor with research interests in the molecular epidemiology of Salmonella in poultry, public health and environment and development.

References

  1. 1 2 Devex (22 February 2024). "About Botswana Vaccine Institute". Devex.com. Retrieved 22 February 2024.
  2. BVI (22 February 2024). "Physical Address of Botswana Vaccine Institute". Botswana Vaccine Institute (BVI). Gaborone, Botswana. Retrieved 22 February 2024.
  3. WOAH (4 November 2011). "New FMD vaccine launch BVI". World Organisation for Animal Health (WOAH). Paris, France. Retrieved 22 February 2024.
  4. Pauline Dikuelo (16 August 2022). "BVI diversifies product offering". Mmegi Online . Gaborone, Botswana. Retrieved 22 February 2024.
  5. J. Falconer & J. J. Guinet (1985). "Botswana Vaccine Institute — Future Regional Laboratory for Rabies Vaccine Production". Rabies in the Tropics. Springer, Berlin, Heidelberg: 679–682. doi:10.1007/978-3-642-70060-6_90. ISBN   978-3-540-13826-6 . Retrieved 22 February 2024.
  6. Tonny Abet (21 February 2024). "Uganda, Botswana join hands in search for FMD vaccine". Daily Monitor . Kampala, Uganda. Retrieved 22 February 2024.

24°37′29″S25°55′16″E / 24.62472°S 25.92111°E / -24.62472; 25.92111