CLTB

CLTB
Identifiers
Aliases	CLTB , LCB, clathrin light chain B
External IDs	MGI: 1921575 HomoloGene: 37532 GeneCards: CLTB
Gene location (Human)
Chr.	Chromosome 5 (human) [1]
End	176,416,569 bp [1]
Gene location (Mouse)
Chr.	Chromosome 13 (mouse) [2]
End	54,611,344 bp [2]
Gene ontology
Molecular function	• clathrin heavy chain binding ; • peptide binding ; • protein binding ; • structural molecule activity ;
Cellular component	• ciliary membrane ; • clathrin-coated pit ; • clathrin coat of trans-Golgi network vesicle ; • membrane ; • cytoplasmic vesicle membrane ; • cytoplasmic vesicle ; • clathrin coat of coated pit ; • intracellular membrane-bounded organelle ; • trans-Golgi network ; • clathrin vesicle coat ; • clathrin coat ; • plasma membrane ; • cytosol ; • synaptic vesicle membrane ; • clathrin-coated endocytic vesicle ; • presynaptic endocytic zone membrane ; • postsynaptic endocytic zone cytoplasmic component ;
Biological process	• clathrin-dependent endocytosis ; • vesicle-mediated transport ; • intracellular protein transport ; • membrane organization ; • clathrin coat assembly ;
	Sources:Amigo / QuickGO
Orthologs
	1212
	74325
	ENSG00000175416
	ENSMUSG00000047547
	P09497
	Q6IRU5
	NM_001834 ; NM_007097 ; NM_001364126 ; NM_001364127
	NM_028870 ; NM_001347512
	NP_001825 ; NP_009028 ; NP_001351055 ; NP_001351056 ; NP_001825.1
	NP_001334441 ; NP_083146
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated June 04, 2019 • a couple of secsFrom Wikipedia, The Free Encyclopedia

Clathrin, light chain B is a protein in humans that is encoded by the CLTB gene.^[5]

Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and coated vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000175416 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000047547 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ "Entrez Gene: Clathrin, light chain B" . Retrieved 2013-06-05.

CLTB

Related Research Articles

References

Further reading