Camptodactyly-taurinuria syndrome

Last updated
Camptodactyly-taurinaria syndrome
Other namesFamilial streblodactyly with amino aciduria
Specialty Medical genetics
Symptoms permanent flexion of the fingers of the hand (camptodactyly, and high leves of taurine in urine
Usual onsetInfancy
Durationlife-long
Causes Genetic mutation
Preventionnone
Prognosis good
Frequencyvery rare, less than 20 cases reported worldwide

Camptodactyly-taurinuria syndrome, also known as familial streblodactyly with amino aciduria is a very rare autosomal dominant genetic disorder which consists of hand camptodactyly (usually affecting the pinky finger) and high levels of taurine in urine due to over-excretion of it. 17 affected people from 4 families across the world have been reported in medical literature. No new cases have been described since 1966. [1] [2] [3] [4] It is believed to be autosomal dominant. [1]

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References

  1. 1 2 "Camptodactyly taurinuria - About the Disease - Genetic and Rare Diseases Information Center". rarediseases.info.nih.gov. Retrieved 2022-05-11.
  2. "Camptodactyly-Taurinuria Syndrome". DoveMed. Retrieved 2022-05-11.
  3. "Open Targets Platform". platform.opentargets.org. Retrieved 2022-05-11.
  4. RESERVED, INSERM US14-- ALL RIGHTS. "Orphanet: Familial streblodactyly with amino aciduria". www.orpha.net. Retrieved 2022-05-11.{{cite web}}: CS1 maint: numeric names: authors list (link)