Can f 1

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Can f 1 or canis familiaris allergen 1 is a lipocalin [1] allergen produced by dogs [2] in their tongue epithelial tissue. [3] It is homologous with the human lipocalin LCN1. [4] [5]

References

  1. ↑ Major allergen Can f 1 UniProtKB.
  2. ↑ Grammer, Leslie C. and Paul A. Greenberger (2009), Patterson's Allergic Diseases p. 97.
  3. ↑ Konieczny, A; Morgenstern, J P; Bizinkauskas, C B; Lilley, C H; Brauer, A W; Bond, J F; Aalberse, R C; Wallner, B P; Kasaian, M T (December 1997). "The major dog allergens, Can f 1 and Can f 2, are salivary lipocalin proteins: cloning and immunological characterization of the recombinant forms". Immunology. 92 (4): 577–586. doi:10.1046/j.1365-2567.1997.00386.x. ISSN   0019-2805. PMC   1364166 . PMID   9497502.
  4. ↑ Jensen-Jarolim, E.; Pacios, L.F.; Bianchini, R.; Hofstetter, G.; Roth-Walter, F. (March 2016). "Structural similarities of human and mammalian lipocalins, and their function in innate immunity and allergy". Allergy. 71 (3): 286–294. doi:10.1111/all.12797. ISSN   0105-4538. PMC   4949658 . PMID   26497994.
  5. ↑ Breitenbuecher, Christina; Belanger, Janelle M.; Levy, Kerinne; Mundell, Paul; Fates, Valerie; Gershony, Liza; Famula, Thomas R.; Oberbauer, Anita M. (2016-04-22). "Protein expression and genetic variability of canine Can f 1 in golden and Labrador retriever service dogs". Canine Genetics and Epidemiology. 3: 3. doi: 10.1186/s40575-016-0031-3 . ISSN   2052-6687. PMC   4840867 . PMID   27110374.
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