Carol Gross

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Carol Gross
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Carol A. Gross is a molecular biologist and professor of cell and tissue biology at the University of California San Francisco (UCSF). [1] Her research focuses on transcriptional regulation in bacteria. [2]

Contents

Research and career

At UCSF Dr. Carol A. Gross runs a lab that takes genetic, biochemical, and systems approaches to study regulatory mechanisms of E. coli stress responses, protein interactions in the bacterial transcription apparatus, and genome-wide control of gene expression. [3] She is a Member of the National Academy of Sciences, a Fellow of the American Academy of Arts and Sciences, and a Fellow of the American Association for the Advancement of Science (AAAS)

Among her notable contributions to the field of microbiology was the discovery, in collaboration with several other scientists, of the Extracytoplasmic Function (ECF) σ factors, proteins that subsequently emerged as the largest group of alternative σ factors and one of the three major pillars of signal transduction in bacteria, alongside one- and two-component systems. [4]

Gross studied botany at Cornell University, then obtained a masters' degree in science education at Brooklyn College. [5] She then went on to earn a PhD in 1968 from the University of Oregon at the Institute of Molecular Biology under the biophysicist Aaron Novick. [6] [7]

As of mid-2023 Gross had authored or co-authored 176 academic publications dating back to 1974. Her most recent co-authored scientific journal article was published in April 2023. She serves as Principal Investigator for a study funded by the National Institutes of Health studying cellular homeostasis pathways in bacteria. [8]

As a distinguished professor and researcher Gross has been recognized for her commitment to and advocacy for diversity in STEM education. [9]

Before working at UCSF, Gross was a postdoctoral researcher and then faculty member at the University of Wisconsin Madison. [10]

Personal life

Gross grew up in Brooklyn, New York, and was encouraged to pursue her scientific interests by a high school biology teacher. [11]

Gross married Harrison Echols, also a molecular biologist. After his death in 1993 she edited and published his book, Operators and Promoters: The Story of Molecular Biology and Its Creators, about the birth and early development of the field of molecular biology. [12] [13]

Gross told an interviewer in 2017 that she is Jewish, that her family "wasn't very wealthy," and that she "didn't grow up thinking that life was fair." She recounted: "When I went to Cornell, I ended up taking the worst physics course, and one semester of the organic chemistry course because I couldn’t afford to pay more to take additional classes." Gross gave birth soon after starting her PhD studies, and recalls that her advisor warned her that it was not possible to be both a good scientist and a good mother, but that he supported her when she said she would not give up. After she finished her PhD, he told her: “Carol, you really changed my mind.” Informed by her own life experiences she started a faculty diversity committee at UCSF and helped reconfigure a basic sciences summer program for diverse students. [14]

Awards

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References

  1. ↑ "Carol Gross, PhD". UCSF Department of Cell and Tissue Biology. University of California San Francisco. Retrieved 26 May 2023.
  2. ↑ "Carol Gross, PhD". Biomedical Sciences Graduate Program. Retrieved 5 October 2018.
  3. ↑ "Carol Gross, PhD". UCSF Department of Cell and Tissue Biology. University of California San Francisco. Retrieved 26 May 2023.
  4. ↑ Lonetto, Michael A.; Donohue, Timothy J.; Gross, Carol A.; Buttner, Mark J. (August 2019). "Discovery of the extracytoplasmic function σ factors". Molecular Microbiology. 112 (2): 348–355. doi:10.1111/mmi.14307. PMC   8384415 . PMID   31115926.
  5. ↑ Tatapudy, Sumitra (11 May 2017). "Advocate Shares Her Story". University of California San Francisco. Synapse: UCSF Student Voices. Retrieved 26 May 2023.
  6. ↑ "Carol A. Gross". Chemistry Tree. Academic Tree. Retrieved 26 May 2023.
  7. ↑ TACHIBANA, CHRIS. "University of Oregon's Institute of Molecular Biology Celebrates 50 Years" (PDF). ASBMB TODAY. AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY. Retrieved 26 May 2023.
  8. ↑ "Carol Gross, PhD". UCSF Profiles. University of California San Francisco. Retrieved 26 May 2023.
  9. ↑ Tatapudy, Sumitra (11 May 2017). "Advocate Shares Her Story". University of California San Francisco. Synapse: UCSF Student Voices. Retrieved 26 May 2023.
  10. ↑ "Carol A. Gross, Ph.D. | McArdle Laboratory for Cancer Research". mcardle.wisc.edu.
  11. ↑ Tatapudy, Sumitra (11 May 2017). "Advocate Shares Her Story". University of California San Francisco. Synapse: UCSF Student Voices. Retrieved 26 May 2023.
  12. ↑ Echols, Harrison (2001). Operators and Promoters: The Story of Molecular Biology and Its Creators. Berkeley and Los Angeles: University of California Press. ISBN   0-520-21331-9.
  13. ↑ Hughes, Sally Smith (2002). "Review of Operators and Promoters: The Story of Molecular Biology and Its Creators". Bulletin of the History of Medicine. 46 (4): 860–861. doi:10.1353/bhm.2002.0184 . Retrieved 26 May 2023.
  14. ↑ Tatapudy, Sumitra (11 May 2017). "Advocate Shares Her Story". University of California San Francisco. Synapse: UCSF Student Voices. Retrieved 26 May 2023.
  15. ↑ "Carol Gross". www.nasonline.org. Retrieved 5 October 2018.
  16. ↑ "STEM MENTORING: EMERGING STRATEGIES FOR INCLUSION A Summary of the 2016 and 2017 STEM Mentors Alumni Meetings" (PDF). National Science Foundation & American Association for the Advancement of Science. Retrieved 26 May 2023.
  17. ↑ "Selman A. Waksman Award in Microbiology". www.nasonline.org. Retrieved 5 October 2018.
  18. ↑ "ASM Lifetime Achievement Award, American Society for Microbiology". American Society for Microbiology. Retrieved 26 May 2023.
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