Leprosy, also known as Hansen's disease (HD), is a long-term infection by the bacteria Mycobacterium leprae or Mycobacterium lepromatosis. Infection can lead to damage of the nerves, respiratory tract, skin, and eyes. This nerve damage may result in a lack of ability to feel pain, which can lead to the loss of parts of a person's extremities from repeated injuries or infection through unnoticed wounds. An infected person may also experience muscle weakness and poor eyesight. Leprosy symptoms may begin within one year, but, for some people, symptoms may take 20 years or more to occur.
Gerhard Henrik Armauer Hansen was a Norwegian physician, remembered for his identification of the bacterium Mycobacterium leprae in 1873 as the causative agent of leprosy. His distinguished work was recognized at the International Leprosy Congress held at Bergen in 1909.
Iberville Parish is a parish located south of Baton Rouge in the U.S. state of Louisiana, formed in 1807. The parish seat is Plaquemine. The population was 30,241 at the 2020 census.
A leper colony, also known by many other names, is an isolated community for the quarantining and treatment of lepers, people suffering from leprosy. M. leprae, the bacterium responsible for leprosy, is believed to have spread from East Africa through the Middle East, Europe, and Asia by the 5th century before reaching the rest of the world more recently. Historically, leprosy was believed to be extremely contagious and divinely ordained, leading to enormous stigma against its sufferers. Other severe skin diseases were frequently conflated with leprosy and all such sufferers were kept away from the general public, although some religious orders provided medical care and treatment. Recent research has shown M. leprae has maintained a similarly virulent genome over at least the last thousand years, leaving it unclear which precise factors led to leprosy's near elimination in Europe by 1700. A growing number of cases following the first wave of European colonization, however, led to increased attention towards leprosy during the New Imperialism of the late 19th century. Following G.A. Hansen's discovery of the role of M. leprae in the disease, the First International Leprosy Conference held in Berlin in 1897 renewed interest and investment in the isolation of lepers throughout the European colonial empires. Although Western countries now generally treat cases of leprosy individually on an outpatient basis, traditional isolated colonies continue to exist in India, China, and some other countries.
The Bureau of Primary Health Care (BPHC) is a part of the Health Resources and Services Administration (HRSA), of the United States Department of Health and Human Services. HRSA helps fund, staff and support a national network of health clinics for people who otherwise would have little or no access to care. BPHC funds health centers in underserved communities, providing access to high quality, family oriented, comprehensive primary and preventive health care for people who are low-income, uninsured or face other obstacles to getting health care.
Paul Wilson Brand, was a pioneer in developing tendon transfer techniques for use in the hands of those with leprosy. He was the first physician to appreciate that leprosy is not a disease of the tissue but of the nerves: it is the loss of the sensation of pain which makes sufferers susceptible to injury and leads to tissue rotting away, especially in the extremities. Brand contributed extensively to the fields of hand surgery and hand therapy through his publications and lectures, and wrote popular autobiographical books about his childhood, his parents' missionary work, and his philosophy about the valuable properties of pain. One of his best-known books, co-written with Christian writer Philip Yancey, is Pain: The Gift Nobody Wants (1993), republished in 1997 as The Gift of Pain.
The Louisiana Political Museum and Hall of Fame is a museum and hall of fame located in Winnfield, Louisiana. Created by a 1987 act of the Louisiana State Legislature, it honors the best-known politicians and political journalists in the state.
Leprosy stigma is a type of social stigma, a strong negative feeling towards a person with leprosy relating to their moral status in society. It is also referred to as leprosy-related stigma, leprostigma, and stigma of leprosy. Since ancient times, leprosy instilled the practice of fear and avoidance in many societies because of the associated physical disfigurement and lack of understanding behind its cause. Because of the historical trauma the word "leprosy" invokes, the disease is now referred to as Hansen's disease, named after Gerhard Armauer Hansen who discovered Mycobacterium leprae, the bacterial agent that causes Hansen's disease. Those who have suffered from Hansen's disease describe the impact of social stigma as far worse than the physical manifestations despite it being only mildly contagious and pharmacologically curable. This sentiment is echoed by Weis and Ramakrishna, who noted that "the impact of the meaning of the disease may be a greater source of suffering than symptoms of the disease".
As of 2009, 2,600 former leprosy patients were living in 13 national sanatoriums and 2 private hospitals in Japan. Their mean age is 80. There were no newly diagnosed Japanese leprosy patients in 2005, but one in 2006, and one in 2007.
Guy Henry Faget (1891–1947) was an American medical doctor who revolutionalized the treatment of leprosy, by demonstrating the efficacy of promin, as described in a paper published in 1943. Promin is a sulfone compound, synthesized by Feldman and his co-workers in 1940, which is a chemotherapeutic agent that was determined to be effective against tuberculosis in experimental animals. He was the grandson of Jean Charles Faget, and father of Maxime Faget.
Kusatsu Special Prison was a prison that operated between 1938 and 1947, in Kuryu Rakusen-en Sanatorium in Kusatsu Onsen, Kusatsu town, Gunma Prefecture, Japan, where criminals from public leprosaria throughout Japan were imprisoned. Prisons for conventional crimes had been built earlier in all public leprosaria. A total of 22 out of 93 prisoners died of cold or maltreatment in the cells or after confinement. In Japanese, it was called Tokubetsu Byoshitsu or Jyu Kanbo.
Promin, or sodium glucosulfone is a sulfone drug that was investigated for the treatment of malaria, tuberculosis and leprosy. It is broken down in the body to dapsone, which is the therapeutic form.
Although leprosy, or Hansen's Disease, was never an epidemic in The United States, cases of leprosy have been reported in Louisiana as early as the 18th century. The first leprosarium in the continental United States existed in Carville, Louisiana from 1894-1999 and Baton Rouge, Louisiana is the home of the only institution in the United States that is exclusively devoted to leprosy consulting, research, and training.
Louisiana Highway 141 (LA 141) is a state highway located in Iberville Parish, Louisiana. It exists in two disconnected sections totaling 4.07 miles (6.55 km) along Point Clair Road within the city of St. Gabriel.
The Carville Historic District in Carville, Louisiana, is a 60-acre (24 ha) historic district that was listed on the National Register of Historic Places on November 18, 1992. It formerly served as a treatment facility for leprosy, and was called the National Leprosarium, Gillis W. Long Hansen's Disease Center and Public Health Service Hospital No. 66.
The Bureau of Medical Services (BMS) was a unit of the United States Public Health Service (PHS) that existed in two incarnations. The first was one of three principal operating agencies of PHS from 1943 until 1966, while the second was a division of the PHS Health Services Administration from 1973 until 1982. Both incarnations of the bureau had the principal responsibility of operating the PHS hospital system that had been founded in 1789.
Josefina Guerrero was a Filipina spy during World War II. Guerrero had leprosy and was an unsuspicious and effective surveillance asset for American allied forces.
Ernest Muir FRCS, CIE, CMG was a Scottish medical missionary and educator in British-controlled India and Nigeria most noted for his work with Hansen's disease (leprosy).
Regina Purtell (1866–1950) was an American Roman Catholic sister and United States Army nurse. She cared for Theodore Roosevelt's "Rough Riders", and the media dubbed her "The Florence Nightingale of the Spanish-American War."
