Center for BrainHealth

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The Center for BrainHealth

The Center for BrainHealth, part of The University of Texas at Dallas' school of Behavioral and Brain Sciences, is a research institute focused exclusively on brain health that combines brain research with clinical interventions. Founded by Dr. Sandra Bond Chapman in 1999, [1] the Center for BrainHealth houses 125 researchers, postdoctoral research fellows, doctoral students, master's students, and research clinicians who work on 60 privately and federally funded research projects. The Center provides academic training and houses specialists in, among many others, Alzheimer's disease, traumatic brain injury (TBI), healthy brain aging, multiple sclerosis, autism, attention deficit hyperactivity disorder (ADHD), stroke, and posttraumatic stress disorder (PTSD). To help raise awareness of and funding for research underway at the Center for BrainHealth, a number of proponent groups have formed. These include the Think Ahead Group (TAG) of young professionals and Friends of BrainHealth. [2]

Contents

Research

Researchers work side-by-side with clinicians. Brain scientists at the Center use technologies to elucidate how brain networks can be strengthened and reconnected, including electroencephalography (EEG) to record the brain's electrical rhythms during cognitive task performance, functional MRI (fMRI) scans to measure brain blood flow during cognitive tasks, an indicator of brain activity and brain morphometrics to measure size and shape differences of brain regions to millimeter accuracy. [3] The Center houses specialists in various fields of neuroscience, and has produced publications from members of the BrainHealth Team. [4] Research initiatives include:

Healthy Brain•Provide BrainHealth Fitness Checkups, cognitive-linguistic assessments to establish baseline function, highlight strengths, identify weaknesses, and provide recommendations to preserve mental abilities

•Expand the knowledge of improving of corporate environments by increasing workforce mental productivity, looking for ways to strengthen the brain's frontal lobes, take advantage of dramatic brain plasticity as people age, and challenge mental talents and capacities.

Semantic Memory Processing in Normal Adults•Establish localization of brain regions associated with different sub-types of memory
Brain Training•Evaluate the effect of novel brain training in normally aging adults
Traumatic Brain Injury/Stroke•Cognitive and social outcome of pediatric TBI: Investigating impact of impairments on academic, social, and psychological functioning
•Memory deficits following pediatric TBI: Evaluating changes in working memory and related brain activation in those with head injury
•Brain imaging and genetics in Social Cognition: establishing battery to assess social cognition
•Genetic factors and outcome from TBI: examining a predisposition to recovery potential after brain injury
•Growth and abnormalities after pediatric TBI: developing procedures for medical testing and treatment
•Self regulation abilities in children with severe TBI: development of self-regulation evaluation tools for children with severe brain injury and the subsequent foundation for rehabilitation
•Cognitive retraining and memory dysfunction in brain injury of adults: neuroimaging biomarkers and diagnostic tools for working memory and semantic memory deficits in head injury and cognitive rehabilitation treatment paradigm
Gulf War syndrome•Development of diagnostic criteria for Gulf War Syndrome
Attention deficit hyperactivity disorder•Development and implementation of strategic memory and reasoning training (SMART) intervention program
Autism spectrum disorders•Establish assessment battery for social cognition
•Development of various intervention programs using virtual computer technology
Dementia•Language of Hereditary Dysphasic Disinhibition Dementia: examination of linguistic markers of early disease onset
•Discourse Assessment of Frontotemporal Lobar Degeneration (FTLD):analysis of language to differentiate differences between subtypes of FTLD, Alzheimer's, and healthy controls
•Semantic Memory and Gist Performance in Frontotemporal Lobar Degeneration, Mild Cognitive Impairment, and Alzheimer's using fMRI and EEG: characterizing language distinctions in populations
Military Service Members and the Brain•Proactively optimizing brain performance [5]
•Building resilience in cognitive brain function [5]
•Reversing losses in cognitive capacity [5]
Post Traumatic Stress Disorder•Combining Cognitive processing therapy (CPT) and repetitive transcranial magnetic stimulation (rTMS). [6]
•No-cost, non-drug clinical trial to further investigate the effectiveness of a paired treatment [6]

History

Dr. Sandra Bond Chapman and a colleague Haley Scans 071205 19892.jpg
Dr. Sandra Bond Chapman and a colleague

The Center for BrainHealth, part of The University of Texas at Dallas (UTD), was established in 1999 under the direction of Dr. Sandra Bond Chapman, UT Dallas' Dee Wyly Distinguished Chair in Brain Health. [7] Originally located at UT Dallas' Callier Center for Communication Disorders, in 2004 the Texas Higher Education Coordinating Board approved the purchase and renovation of a nearby building at 2200 Mockingbird Lane in Dallas to be the Center's own facility. This facility is adjacent to the UT Southwestern North Campus. The Center's virtual lab is part of the National Pediatric Acquired Brain Injury Plan, and in 2004 the BrainHope Program was established for children with traumatic brain injuries. Also in 2004, Dee and Charles Wyly endowed the $2-million Dee Wyly Distinguished Chair at the Center and a $1.5-million gift from Sallie and Frederic B. Asche, Jr., to enable the establishment of the Sallie and Frederic B. Asche Jr. Advanced Treatment Wing at the Center for BrainHealth. [8] [9] In 2005 the Center received a $2-million gift to endow a chair for the Center's medical science director. [10] The Center's memory research initiatives were expanded in 2006 with $1 million to establish the Berman Laboratory for Learning and Memory and the Berman Scholars Program for young researchers doing postdoctoral training in memory. [11] In 2007, businessman and philanthropist T. Boone Pickens donated $5 million to the Center for BrainHealth to fund educational and research initiatives in the area of brain science. [12] In 2008, the Center's Middle School Brain Years project conducted the pilot study of its Strategic Memory and Reasoning Training (SMART) Program, an experimental curriculum designed to improve strategic reasoning skills in teens. The pilot study's success led to a $6 million grant from Texas Legislature for the project's expansion. [13]

Facilities

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The Frances and Mildred Goad Building

The Center for BrainHealth is located in a 63,000-square-foot (5,900 m2) building designed by Kyley Harvey of HKS, Inc., on a 3.5 acres (0.014 km2) site near the UT Dallas' Callier Center for Communication Disorders and the University of Texas Southwestern Medical Center in the city of Dallas. In 2004, UT Dallas purchased a building with a $5 million donation from Dianne Cash. The new building was named the Frances and Mildred Goad Building in honor of Cash's mother, who benefited from the Center's efforts, and grandmother. [14] Originally constructed in 1970, the redesign and remodel was an extensive undertaking that began in June 2005, completed in September 2006, with the building formally dedicated on January 26, 2007. [15] [16] Each floor of the facility is dedicated to carrying out one aspect of BrainHealth's mission and includes an auditorium, virtual classrooms, the T. Boone Pickens Virtual Learning Center, and a reception hall. The second floor contains computers and data analysis tools, as well as an outlet for brain scientists, engineers, and technology experts to explore data. The third floor houses clinically based research projects, including a facility for individuals to undergo brain fitness checkups for discovering ways to prevent memory decline and a place for adults and children to participate in research aimed at learning more about how to strengthen brain function after injury or disease. The Center for BrainHealth houses electroencephalography labs, data analysis tools, MRI machines, an rTMS (Repetitive Transcranial Magnetic Stimulation) lab, and brain morphometric laboratories. [17]

Think Ahead Group

Think Ahead Group (TAG) is a young professionals group based in Dallas, Texas, that raises awareness of brain health and funds for research taking place at the Center for BrainHealth.

The Think Ahead Group, founded in October 2009, now includes over 300 members. All contributions support the cause of brain health and the Center's many research focus areas-Alzheimer's disease, traumatic brain injury (TBI), autism, attention deficit hyperactivity disorder (ADHD), stroke, posttraumatic stress disorder (PTSD), addiction, BrainHealth physical, dementia, exercise and the brain, healthy brain aging, and virtual brain training.

Directors

Related Research Articles

Post-traumatic stress disorder (PTSD) is a mental and behavioral disorder that can develop because of exposure to a traumatic event, such as sexual assault, warfare, traffic collisions, child abuse, domestic violence, or other threats on a person's life. Symptoms may include disturbing thoughts, feelings, or dreams related to the events, mental or physical distress to trauma-related cues, attempts to avoid trauma-related cues, alterations in the way a person thinks and feels, and an increase in the fight-or-flight response. These symptoms last for more than a month after the event. Young children are less likely to show distress but instead may express their memories through play. A person with PTSD is at a higher risk of suicide and intentional self-harm.

University of Texas System Public university system in Texas

The University of Texas System is an American government entity of the state of Texas that includes 13 higher educational institutions throughout the state including eight universities and five independent health institutions. The UT System is headquartered in Downtown Austin, and has a total enrollment of nearly 240,000 students and employs 21,000 faculty and more than 83,000 health care professionals, researchers and support staff. The UT System's $30 billion endowment is the largest of any public university system in the United States. As of 2018, Reuters ranks the UT System among the top 10 most innovative academic institutions in the world.

West Texas A&M University Public university in Canyon, Texas, United States

West Texas A&M University is a public university in Canyon, Texas. It is the northernmost campus of the Texas A&M University System and accredited by the Southern Association of Colleges and Schools (SACS). It was established on September 20, 1910, as West Texas State Normal College as one of the seven state-funded teachers' colleges in Texas.

University of Texas at Dallas Public university in Richardson, Texas

The University of Texas at Dallas is a public research university in Richardson, Texas. It is one of the largest public universities in the Dallas area and the northernmost institution of the University of Texas system. It was initially founded in 1961 as a private research arm of Texas Instruments.

The University of Texas Southwestern Medical Center is a public academic health science center in Dallas, Texas. With approximately 13,568 employees and 2,445 faculty and over 2.7 million outpatient visits per year, UT Southwestern is the largest medical school in the University of Texas System and state of Texas.

MD Anderson Cancer Center Hospital in Texas, United States of America

The University of Texas MD Anderson Cancer Center is a comprehensive cancer center in Houston, Texas. It is the largest cancer center in the U.S. and one of the original three comprehensive cancer centers in the country. It is both a degree-granting academic institution and a cancer treatment and research center located at the Texas Medical Center in Houston. It is affiliated with The University of Texas Health Science Center at Houston. According to Newsweek, MD Anderson Cancer Center is considered the best hospital in the world for oncology and related cancer treatment.

The Institute of Biosciences and Technology (IBT), a component of the Texas A&M Health Science Center represents the Texas A&M University System, one of the two main Texas state university systems, in the state's and world's largest medical center, the Texas Medical Center, in Houston, Texas. The institute provides a bridge between Texas A&M University System scientists and other institutions' researchers working in the Texas Medical Center and the biomedical and biotechnology research community in Houston. It emphasizes collaboration between member scientists and others working in all the fields of the biosciences and biotechnology. IBT encourages its scientists to transfer discoveries made in their laboratories to the clinic and marketplace.

T. Boone Pickens American financier (1928–2019)

Thomas Boone Pickens Jr. was an American business magnate and financier. Pickens chaired the hedge fund BP Capital Management. He was a well-known takeover operator and corporate raider during the 1980s. As of November 2016, Pickens had a net worth of $500 million.

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Dee and Charles Wyly Theatre

The Dee and Charles Wyly Theatre is a theatre at the AT&T Performing Arts Center, located in the Arts District of downtown Dallas, Texas (USA). It is one of four venues that comprise the AT&T Performing Arts Center and was dedicated October 12, 2009. The 80,300-square-footbuilding is twelve stories and holds about 600 people, depending upon the stage configuration. It is the new venue for the Dallas Theater Center, Dallas Black Dance Theatre and Anita N. Martinez Ballet Folklorico.

University of Texas at Dallas academic programs

The University of Texas at Dallas is a public research university in the University of Texas System. The University of Texas at Dallas main campus is located in Richardson, Texas.

Sandra Bond Chapman

Sandra Bond Chapman is a cognitive neuroscientist, founder and chief director of the Center for BrainHealth, Dee Wyly Distinguished Professor in Brain Health, and a professor in the School of Behavioral and Brain Sciences at The University of Texas at Dallas.

Frank Harrison (academic)

Frank Harrison Jr. was an American physician, professor and university administrator.

Peter J. O'Donnell, Jr. was an American businessman, securities investor and philanthropist. From 1962 to 1969, he was the Texas Republican state chair. In 1963, he was also the national chair of the Draft Goldwater Committee.

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Richard Bryant (psychologist) Australian psychologist

Richard Allan Bryant is an Australian medical scientist. He is Scientia Professor of Psychology at the University of New South Wales (UNSW) and director of the UNSW Traumatic Stress Clinic, based at UNSW and Westmead Institute for Medical Research. His main areas of research are posttraumatic stress disorder (PTSD) and prolonged grief disorder. On 13 June 2016 he was appointed a Companion of the Order of Australia (AC), for eminent service to medical research in the field of psychotraumatology, as a psychologist and author, to the study of Indigenous mental health, as an advisor to a range of government and international organisations, and to professional societies.

K. Drorit “Dee” Gaines is a neuropsychologist specializing in diagnostic evaluations, brain injury, trauma, and public education. She is most known for her work with United States veterans, and serves as an authority on the physical brain’s effects on behavior and cognitive functioning.

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Kenneth Z. Altshuler American psychiatrist and psychoanalyst

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References

  1. "SANDRA BOND CHAPMAN CENTER FOR BRAINHEALTH" (PDF). TheBrainProject.org. The University of Texas at Dallas. November 13, 2008. Retrieved July 23, 2010.
  2. "Center for BrainHealth". The Center for Brain Health. The University of Texas at Dallas. Retrieved July 23, 2010.
  3. "Research". Center for BrainHealth. The University of Texas at Dallas. Retrieved 2010-07-24.
  4. "Publications". Center for BrainHealth. The University of Texas at Dallas. Retrieved July 25, 2010.
  5. 1 2 3 "Military Service Members and the Brain". Center for BrainHealth. The University of Texas at Dallas. Retrieved April 4, 2015.
  6. 1 2 "Center for BrainHealth -PTSD". The University of Texas at Dallas. Retrieved 2015-04-04.
  7. "Timeline 40 Years". The University of Texas at Dallas. Retrieved July 23, 2010.
  8. "Dee and Charles Wyly to Endow $2-Million Chair at U.T. Dallas' Center for BrainHealth". Dallas Business Journal. March 16, 2004. Retrieved July 24, 2010.
  9. "$1.5-Million Gift to Center for BrainHealth to Fund New Wing for Treatment of Strokes, Brain Injuries". The University of Texas at Dallas. Retrieved July 24, 2010.
  10. "Dallas Couple Donates $2 Million to BrainHealth Center To Endow Distinguished Chair for Medical Director". The University of Texas at Dallas. Retrieved July 24, 2010.
  11. "The Dallas Morning News Robert Miller column: BrainHealth center gets memorable gift". The Dallas Morning News. May 15, 2006. Retrieved July 23, 2010.[ dead link ]
  12. "T. Boone Pickens Donates $5 MillionTo UT Dallas to Advance Brain Health". The University of Texas at Dallas. Archived from the original on September 3, 2010. Retrieved July 24, 2010.{{cite web}}: CS1 maint: unfit URL (link)
  13. "UT Dallas researchers hope to train teens in reasoning skills". The Dallas Morning News. September 8, 2008. Archived from the original on October 10, 2008. Retrieved July 23, 2010.{{cite news}}: CS1 maint: unfit URL (link)
  14. "BrainHealth Building". The UTD Mercury. Archived from the original on July 22, 2011. Retrieved July 23, 2010.
  15. "TSA Design Award" (PDF). Center for BrainHealth. The University of Texas at Dallas. Archived from the original on June 17, 2010. Retrieved July 25, 2010.{{cite web}}: CS1 maint: unfit URL (link)
  16. "Texas Architect Design Award". Texas Society of Architects. Retrieved 2010-07-25.
  17. "Facilities". Center for BrainHealth. The University of Texas at Dallas. Retrieved July 23, 2010.
  18. 1 2 3 "Directors". Center for BrainHealth. The University of Texas at Dallas. Archived from the original on July 10, 2010. Retrieved July 23, 2010.{{cite web}}: CS1 maint: unfit URL (link)

Coordinates: 32°49′29″N96°50′52″W / 32.824620°N 96.847675°W / 32.824620; -96.847675