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Company type | Non-profit organization |
---|---|
Industry | Biomedical research, Global health, Infectious disease |
Founded | 1976 |
Founder | Ken Stuart |
Headquarters | Seattle, Washington |
Key people | Ken Stuart, President/Founder |
Number of employees | 250+ |
Parent | Seattle Children's Research Institute |
Website | http://www.seattlebiomed.org/ |
Since October 2018, the Center for Global Infectious Disease Research has been part of the Seattle Children's Research Institute. [1] [2] At the time of the merger, CID Research had 166 scientists. Its mission was to eliminate the world's most devastating infectious diseases through leadership in scientific discovery. The organization's research labs were in the South Lake Union area of Seattle, WA. The institute's research focused on four areas of infectious disease: HIV/AIDS, malaria, tuberculosis (TB), and Emerging & Neglected Diseases (END) like African sleeping sickness, leishmaniasis, Chagas disease, and toxoplasmosis.[ citation needed ] CID Research was engaged in early stages of the scientific pipeline including bench science and malaria clinical trials and has expertise in immunology, vaccinology, and drug discovery.[ citation needed ]
In 1976, founders Ruth W. Shearer, Ph.D., and Kenneth Stuart, Ph.D., set up a research laboratory in Issaquah, WA. Originally called the Issaquah Group for Health and Environmental Research, the name was soon changed to Issaquah Biomedical Research Institute. Scientists at the Institute studied parasites including ones that cause malaria and African sleeping sickness. In 1986, the Institute relocated to Seattle, Washington, to enhance its scientific programs and became Seattle Biomedical Research Institute. [3]
In January 2012, Alan Aderem, Ph.D. became president of Seattle BioMed, only the second in its 36-year history, with Stuart remaining in an active role as President Emeritus and Founder. As part of the Institute's plan for scientific expansion, Aderem led the implementation of integrating systems biology approaches to understanding infectious disease. [4] In April 2017, Dr. John Aitchison became the organization's third president and director. [5]
The organization's name was changed to the Center for Infectious Disease Research in April 2015 to better reflect its focus. [6]
Its merger with Seattle Children's Research Institute was announced in July 2018 and finalized on October 1. [7] Until this time, it was the largest independent, non-profit organization in the United States focused solely on infectious disease discovery research.
The Center for Infectious Disease Research performed research on four areas of infectious disease:HIV/AIDS, malaria, tuberculosis (TB), and Emerging & Neglected Diseases (END) like African sleeping sickness, leishmaniasis, Chagas disease, and toxoplasmosis. Seattle is a hub for global health research, and in July 2012, Seattle Magazine honored two Seattle BioMed leaders (Dr. Stuart and Theresa Britschgi, Director of BioQuest) as "Top Docs" for the work they're doing in research and scientific training. [8]
As part of a broad global initiative to fight malaria, CID Research developed its malaria program in 2000, with an initial grant from the Bill & Melinda Gates Foundation. With a three-pronged approach, the organization's malaria program was focused on vaccine discovery for pregnancy malaria, severe malaria in children, and liver-stage malaria. In 2005, it received two Grand Challenges in Global Health grants, which are sponsored by the Gates, to accelerate its malaria research. [9] And in 2011, it was granted another $9 million from the Gates Foundation to support malaria vaccine efforts. [10]
In 2010, Dr. Stefan Kappe developed his own malaria vaccine candidate which was a weakened form of the malaria parasite, and that vaccine candidate was undergoing clinical trials at Walter Reed near Washington, D.C. [11] Soon after, in collaboration with PATH's Malaria Vaccine Initiative, CID Research became home to one of four malaria clinical trial centers in the world where treatments and vaccines could be safely tested in humans using the human challenge model. [12]
One education program offered by CID Research to engage and mobilize the next generation of scientists was BioQuest Academy, a "biomedical boot camp" for 11th graders with over 60 hours (two weeks) of intensive instruction through a global health curriculum. [13] BioQuest Academy was a STEM career pipeline. [14] In fact, according to a study published in the journal PLOS ONE in 2010, "97% of alumni (2005–2008) are attending postsecondary schools throughout North America; eight graduates have already published scientific articles in peer-reviewed journals and/or presented their scientific data at national and international meetings, and 26 have been retained by Seattle BioMed researchers as compensated technicians and interns." [15]
The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency under the Department of Health and Human Services, and is headquartered in Atlanta, Georgia.
The National Institutes of Health, commonly referred to as NIH, is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. Many NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program.
Tropical diseases are diseases that are prevalent in or unique to tropical and subtropical regions. The diseases are less prevalent in temperate climates, due in part to the occurrence of a cold season, which controls the insect population by forcing hibernation. However, many were present in northern Europe and northern America in the 17th and 18th centuries before modern understanding of disease causation. The initial impetus for tropical medicine was to protect the health of colonial settlers, notably in India under the British Raj. Insects such as mosquitoes and flies are by far the most common disease carrier, or vector. These insects may carry a parasite, bacterium or virus that is infectious to humans and animals. Most often disease is transmitted by an insect bite, which causes transmission of the infectious agent through subcutaneous blood exchange. Vaccines are not available for most of the diseases listed here, and many do not have cures.
The National Institute of Allergy and Infectious Diseases is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's mission is to conduct basic and applied research to better understand, treat, and prevent infectious, immunologic, and allergic diseases.
Institute for Systems Biology (ISB) is a non-profit research institution located in Seattle, Washington, United States. ISB concentrates on systems biology, the study of relationships and interactions between various parts of biological systems, and advocates an interdisciplinary approach to biological research.
Texas Biomedical Research Institute, located in San Antonio, Texas, is an independent, non-profit biomedical research institution, specializing in genetics and in virology and immunology. Texas Biomed is funded by government and corporate grants and contracts, and donations from the public.
Alan Aderem is an American biologist, specializing in immunology and cell biology. Aderem's particular focus is the innate immune system, the part of the immune system that responds generically to pathogens. His laboratory's research focuses on diseases afflicting citizens of resource poor countries, including AIDS, malaria, tuberculosis and influenza.
The Walter Reed Army Institute of Research (WRAIR) is the largest biomedical research facility administered by the U.S. Department of Defense (DoD). The institute is centered at the Forest Glen Annex, in the Forest Glen Park part of the unincorporated Silver Spring urban area in Maryland just north of Washington, DC, but it is a subordinate unit of the U.S. Army Medical Research and Development Command (USAMRDC), headquartered at nearby Fort Detrick, Maryland. At Forest Glen, the WRAIR has shared a laboratory and administrative facility — the Sen Daniel K. Inouye Building, also known as Building 503 — with the Naval Medical Research Center since 1999.
PATH is an international, nonprofit global health organization. PATH is based in Seattle with 1,600 employees in more than 70 countries around the world. Its president and CEO is Nikolaj Gilbert, who is also the Managing Director and CEO of Foundations for Appropriate Technologies in Health (FATH), PATH's Swiss subsidiary. PATH focuses on six platforms: vaccines, drugs, diagnostics, devices, system, and service innovations.
La Jolla Institute for Immunology is a non-profit research organization located in La Jolla, San Diego, California. It is located in UC San Diego’s Research Park. The institute researches immunology and immune system diseases. The institute employs 220 M.D.s and Ph.D.s, including 23 faculty members and more than 450 employees. Dr. Mitchell Kronenberg has served as its president and scientific director since 2003. The institute was founded in 1988.
The Vaccine Research Center (VRC), is an intramural division of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), US Department of Health and Human Services (HHS). The mission of the VRC is to discover and develop both vaccines and antibody-based products that target infectious diseases.
The Center for Infectious Disease Research and Policy (CIDRAP) is a center within the University of Minnesota that focuses on addressing public health preparedness and emerging infectious disease response. It was founded in 2001 by Dr. Michael Osterholm, in order to "prevent illness and death from infectious diseases through epidemiological research and rapid translation of scientific information into real-world practical applications and solutions". It is not part of the Center for Disease Control or National Institute of Health.
The American Society of Tropical Medicine and Hygiene (ASTMH) is an Arlington, Virginia-based non-profit organization of scientists, clinicians, students and program professionals whose longstanding mission is to promote global health through the prevention and control of infectious and other diseases that disproportionately afflict the global poor. ASTMH members work in areas of research, health care and education that encompass laboratory science, international field studies, clinical care and country-wide programs of disease control. The current organization was formed in 1951 with the amalgamation of the American Society of Tropical Medicine, founded in 1903, and the National Malaria Society, founded in 1941.
Ken Stuart is the founder of Center for Global Infectious Disease Research, where he continues scientific research on trypanosomes and malaria. In 2010, Stuart received a grant from the Paul G. Allen Family Foundation to continue his research.
Translational Health Science and Technology Institute (THSTI) is a society registered under the Societies Registration Act XXI of 1860. It is also an autonomous institute of the Department of Biotechnology, Ministry of Science and Technology, Government of India. It was set up in 2009 at Gurgaon and is now located in NCR Biotech Science Cluster, Faridabad along with the Regional Center for Biotechnology, Advanced Technology Platforms Center, Small Animal Facility, and Bio-incubator. Envisioned by former secretary of DBT, M. K. Bhan, the centre was created to enable faster transition of lab research to market. Pramod Garg is the executive director of THSTI.
Barry R. Bloom is Harvard University Distinguished Service Professor and Joan L. and Julius H. Jacobson Professor of Public Health in the Department of Immunology and Infectious Diseases and Department of Global Health and Population in the Harvard T.H. Chan School of Public Health in Boston, where he served as dean of the faculty from 1998 through December 31, 2008.
Thomas M. Kariuki is a Kenya biologist who is Chief Executive Officer of the Science for Africa Foundation. Kariuki previously served as the Director of Programmes for the Alliance for Accelerating Excellence in Science in Africa (AESA). He was the Director of the Institute of Primate Research/National Museums of Kenya, for seven years. Kariuki’s research interests have spanned the immunology of neglected infectious diseases and he has been involved in global efforts to develop vaccines, drugs and diagnostics for poverty-related diseases. He has published on vaccines and diagnostics development for schistosomiasis (Bilharzia), malaria and co-infections and on policy issues related to biomedical research and funding. He is a Fellow of the African Academy of Sciences (AAS), Senior Fellowship of the European Foundations Initiative for Neglected Tropical Diseases, Presidential honour of the Order of Grand Warrior of Kenya (OGW) for scientific leadership and public service, Honorary Professor of Research of the Liverpool School of Tropical Medicine, LSTM.
Mary R. Galinski is a professor of medicine at the Emory Vaccine Center, Hubert Department of Global Health of the Rollins School of Public Health, and the Department of Medicine of the Emory University School of Medicine.
John Ring La Montagne was a Mexican-American biomedical scientist who served as the deputy director of the National Institute of Allergy and Infectious Diseases from 1998 to 2004. He specialized in viral vaccines, HIV/AIDS research, and oversaw NIH's biodefense research after the September 11 attacks.
John R. Mascola is an American physician-scientist, immunologist and infectious disease specialist. He was the director of the Vaccine Research Center (VRC), part of the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH). He also served as a principal advisor to Anthony Fauci, director of NIAID, on vaccines and biomedical research affairs. Mascola is the current Chief Scientific Officer for ModeX Therapeutics.