Chi-Chao Chan

Last updated
Chi-Chao Chan
Chi-Chao Chan.jpg
Alma mater Chung Shan Medical College
Johns Hopkins University
Scientific career
Fields Ophthalmic pathology
Institutions National Eye Institute

Chi-Chao Chan is a Chinese-born American ophthalmologist and physician-scientist specialized in the diagnosis and pathology of eye diseases. She joined the National Eye Institute (NEI) as a postdoctoral researcher in 1982 and remained until her retirement in 2015. Chan was promoted in 1999 to senior investigator and chief of the NEI immunopathology section and the histopathology core.

Contents

Education

Chan completed a M.D. at Chung Shan Medical College (Sun Yat-sen University of Medical Sciences) in 1967 [1] [2] just as the Cultural Revolution was commencing. [3] She came to the U.S. via Hong Kong in 1968. [3] Chan learned English at Boston University and took undergraduate courses at Kent State University and Johns Hopkins University. [3] She earned a B.A. (1972) and a second M.D. (1975) at Johns Hopkins. [1]

Chan completed a residency in ophthalmology at Stanford University Medical Center from 1976 to 1979. [1] She did a postdoctoral fellowship in ophthalmic pathology under W. Richard Green  [ Wikidata ] at the Wilmer Ophthalmological Institute from 1979 to 1982. Chan joined the National Eye Institute (NEI) from 1982 to 1986 for a second postdoctoral fellowship in clinical ocular immunology/uveitis in the laboratory of Robert B. Nussenblatt  [ Wikidata ]. [3]

Career

Following her postdoctoral fellowship at the NEI, Chan continued working there as a medical officer. [2] She was promoted in 1992 to chief of the immunopathology section. Chan became chief of the NEI histopathology core in 1999. Her laboratory had a strong relationship with the National Institutes of Health Clinical Center. [3] The core, which had a Clinical Laboratory Improvement Approved (CLIA) certification, received both clinical and experimental specimens, and processes 6000-8000 samples annually. Chan was a mentor to NEI clinical and research post-doctoral and post-baccalaureate fellows. She has helped in the development and improvement of ophthalmology and vision research in China and, in this process, has promoted exchange among ophthalmologists and vision researchers within China, the United States, and the world. [2]

Chan coauthored over 600 publications. Chan's research led to new ways of diagnosing primary vitreoretinal lymphoma (PVRL). Her team discovered that certain changes at the protein and molecular level could be used to help diagnose PVRL earlier, enabling patients to start chemotherapy sooner. She also researched the pathology of uveitis and Von Hippel–Lindau disease and the genetics and pathogenesis of age-related macular degeneration. [3]

Chan received recognitions including the 2010 outstanding achievement award in ophthalmology and visual science for overseas Chinese from the Chinese Ophthalmological Society, a gold fellow appointment from the Association for Research in Vision and Ophthalmology in 2011, and the 2013 senior achievement award of the American Academy of Ophthalmology. [3]

Chan retired in 2015 after 33 years at the NEI. She continued as a scientist emeritus. [3]

Personal life

Upon retirement, Chan relocated to San Francisco to live near her son and grandchildren. [3]

Related Research Articles

<span class="mw-page-title-main">Ophthalmology</span> Field of medicine treating eye disorders

Ophthalmology is a surgical subspecialty within medicine that deals with the diagnosis and treatment of eye disorders. An ophthalmologist is a physician who undergoes subspecialty training in medical and surgical eye care. Following a medical degree, a doctor specialising in ophthalmology must pursue additional postgraduate residency training specific to that field. This may include a one-year integrated internship that involves more general medical training in other fields such as internal medicine or general surgery. Following residency, additional specialty training may be sought in a particular aspect of eye pathology. Ophthalmologists prescribe medications to treat eye diseases, implement laser therapy, and perform surgery when needed. Ophthalmologists provide both primary and specialty eye care - medical and surgical. Most ophthalmologists participate in academic research on eye diseases at some point in their training and many include research as part of their career. Ophthalmology has always been at the forefront of medical research with a long history of advancement and innovation in eye care.

The National Eye Institute (NEI) was established in 1968. It is located in Bethesda, Maryland. The NEI is one of 27 institutes and centers of the US National Institutes of Health (NIH), an agency of the US Department of Health and Human Services. The mission of NEI is to prolong and protect the vision of the American people. The NEI conducts and performs research into treating and preventing diseases affecting the eye or vision.

Neuro-ophthalmology is an academically-oriented subspecialty that merges the fields of neurology and ophthalmology, often dealing with complex systemic diseases that have manifestations in the visual system. Neuro-ophthalmologists initially complete a residency in either neurology or ophthalmology, then do a fellowship in the complementary field. Since diagnostic studies can be normal in patients with significant neuro-ophthalmic disease, a detailed medical history and physical exam is essential, and neuro-ophthalmologists often spend a significant amount of time with their patients.

<span class="mw-page-title-main">Sankara Nethralaya</span> Hospital in Chennai, Kolkata

Sankara Nethralaya is a not-for-profit missionary institution for ophthalmic care headquartered in Chennai, India. In the name "Sankara Nethralaya", "Sankara" is a reference to Adi Shankaracharya and "Nethralaya" means "The Temple of the Eye". Sankara Nethralaya receives patients from India and abroad. Sankara Nethralaya has over 1000 employees and serves around 1500 patients per day, performing over 100 surgeries per day. The annual revenue as per the taxes is close to US$100 million.

<span class="mw-page-title-main">New York Eye and Ear Infirmary</span> Hospital in New York, United States

New York Eye and Ear Infirmary of Mount Sinai (NYEE) is located at East 14th Street and Second Avenue in lower Manhattan, New York City. Founded on August 14, 1820, NYEE is America's first specialty hospital and one of the most prominent in the fields of ophthalmology and otolaryngology in the world, providing primary inpatient and outpatient care in those specialties. Previously affiliated with New York Medical College, as of 2013 it is affiliated with the Icahn School of Medicine at Mount Sinai as a part of the membership in the Mount Sinai Health System.

The Illinois Eye & Ear Infirmary (IEEI) is a center of ophthalmology and otolaryngology research and clinical practice.

<span class="mw-page-title-main">Moran Eye Center</span> Hospital in Utah, United States

The John A. Moran Eye Center at the University of Utah is an ophthalmology clinical care and research facility in the Mountain West. Physicians provide comprehensive care in all ophthalmic subspecialties. Moran supports 15 research laboratories to develop sight-saving treatments. CEO Randall J Olson leads more than 500 employees.

David Glendenning Cogan was an American ophthalmologist.

Bascom Palmer Eye Institute is the University of Miami School of Medicine's ophthalmic care, research, and education center. The institute is based in the Health District of Miami, Florida, and has been ranked consistently as the best eye hospital and vision research center in the nation.

The Filatov Institute is a research institute and a large ophthalmology (eye) hospital in Odesa, Ukraine. It was founded by Vladimir Filatov, an academic ophthalmologist. Its mission is the study of eye diseases and injuries, the training of ophthalmologists and the provision of eye care in Ukraine. The institute has 700 staff including 27 professors.

Julia A. Haller is an American ophthalmologist who is a Professor and Chair of the Department of Ophthalmology at Sidney Kimmel Medical College at Thomas Jefferson University. She also holds the William Tasman, M.D. Endowed Chair at Wills Eye Hospital in Philadelphia, where she is Ophthalmologist-in-Chief.

<span class="mw-page-title-main">Reza Dana</span> American ophthalmologist and immunologist

Reza Dana is the Claes H. Dohlman Professor of Ophthalmology, senior scientist and W. Clement Stone Clinical Research Scholar at Massachusetts Eye and Ear, Harvard Medical School, and director of the Harvard-Vision Clinical Scientist Development Program.

<span class="mw-page-title-main">Emily Chew</span> American ophthalmologist

Emily Ying Chew, M.D., is an American ophthalmologist and an expert on the human retina with a strong clinical and research interest in diabetic eye disease and age-related eye diseases. She currently works for the National Eye Institute (NEI) at the National Institutes of Health (NIH) in Bethesda, Maryland, where she serves as deputy director of the Division of Epidemiology and Clinical Applications (DECA) and the Institute's deputy clinical director. She designs and implements Phase 1, 2 and 3 clinical trials at the NIH Clinical Center. Chew is board certified in ophthalmology.

<span class="mw-page-title-main">V. S. Sangwan</span> Indian ophthalmologist

Virender Singh Sangwan is an Indian ophthalmologist and the Dr. Paul Dubord Chair professor and director of the L. V. Prasad Eye Institute, Hyderabad. Known for his research on limbal stem cells, Sangwan is the founder secretary and an adviser of the Uveitis Society of India. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 2006.

<span class="mw-page-title-main">Daniel M. Albert</span> American ophthalmologist, ocular cancer researcher and medical historian

Daniel M. Albert is an American ophthalmologist, ocular cancer researcher, medical historian, and collector of rare books and ocular equipment. As of 2018, he is Professor of Ophthalmology at the Casey Eye Institute, Oregon Health & Science University.

Gerd Uwe Auffarth is a German eye surgeon and is Chairman of the Department of Ophthalmology at the Heidelberg University Eye Hospital and Head of the David J. Apple Center for Vision Research which includes the David J. Apple International Laboratory for Ocular Pathology.

Philip I. Murray FRCP, FRCS, FRCOphth is Professor of Ophthalmology at the University of Birmingham, in England, and Honorary Consultant Ophthalmologist at the Birmingham and Midland Eye Centre.

<span class="mw-page-title-main">Sarah Coupland</span> Australian clinical pathologist

Sarah Coupland is an Australian-born pathologist and professor who is the George Holt Chair in Pathology at the University of Liverpool. Coupland is an active clinical scientist whose research focuses on the molecular genetics of cancers, with particular interests in uveal melanoma, conjunctival melanoma, intraocular and ocular adnexal lymphomas and CNS lymphoma. Coupland is also an NHS Honorary Consultant Histopathologist at the Royal Liverpool University Hospital. Since 2006, Coupland has been head of the Liverpool Ocular Oncology Research Group; from which she runs a multidisciplinary oncology research group focussing on Uveal melanoma, based in the Department of Molecular and Clinical Cancer Medicine at the University of Liverpool. Her research laboratory is currently located in the Institute of Translational Medicine From April 2014 to December 2019, Coupland was also Director of the North West Cancer Research Centre, @UoL. In both 2019 and 2020, Coupland was included on the 'Pathology Powerlist' on The Pathologist website.

<span class="mw-page-title-main">Janine Austin Clayton</span> American ophthalmologist

Janine Austin Clayton is an American ophthalmologist. She is the NIH associate director for research on women’s health and director of the Office of Women's Health. Clayton was previously the deputy clinical director of the National Eye Institute.

<span class="mw-page-title-main">H. Nida Sen</span> Turkish-American ophthalmologist

Hatice Nida Sen is an ophthalmologist researching mechanisms involved in different forms of human uveitis. She is a clinical investigator at the National Eye Institute.

References

  1. 1 2 3 Bruce, Isaac (November 2012). "Interview with Chi-Chao Chan". Future Medicinal Chemistry . 4 (17): 2139–2140. doi:10.4155/fmc.12.171. ISSN   1756-8919. PMID   23190100.
  2. 1 2 3 "Chi-Chao Chan, M.D." National Institutes of Health. November 29, 2012. Archived from the original on March 21, 2015. Retrieved 2022-02-19.PD-icon.svg This article incorporates text from this source, which is in the public domain .
  3. 1 2 3 4 5 6 7 8 9 "NEI's Chan Retires After 33 Years of Eye-Opening Research" (PDF). NIH Record. July 3, 2015. p. 10. Retrieved 2022-02-19.PD-icon.svg This article incorporates text from this source, which is in the public domain .
PD-icon.svg This article incorporates  public domain material from websites or documents ofthe National Institutes of Health.